WordNet

send a message from one computer to another to check whether it is reachable and active; "ping your machine in the office"
a sharp high-pitched resonant sound (as of a sonar echo or a bullet striking metal)
contact, usually in order to remind of something; "Ill ping my accountant--April 15 is nearing"
hit with a pinging noise; "The bugs pinged the lamp shade"
make a short high-pitched sound; "the bullet pinged when they struck the car"
a silvery soft waxy metallic element of the alkali metal group; occurs abundantly in natural compounds (especially in salt water); burns with a yellow flame and reacts violently in water; occurs in sea water and in the mineral halite (rock salt) (同)Na, atomic number 11
the 16th letter of the Roman alphabet (同)p

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Aldosterone dysregulation with aging predicts renal vascular function and cardiovascular risk.

Brown JM1, Underwood PC, Ferri C, Hopkins PN, Williams GH, Adler GK, Vaidya A.
Hypertension.Hypertension.2014 Jun;63(6):1205-11. doi: 10.1161/HYPERTENSIONAHA.114.03231. Epub 2014 Mar 24.
Aging and abnormal aldosterone regulation are both associated with vascular disease. We hypothesized that aldosterone dysregulation influences the age-related risk of renal vascular and cardiovascular disease. We conducted an analysis of 562 subjects who underwent detailed investigations under condi
PMID 24664291

The anthraquinone drug rhein potently interferes with organic anion transporter-mediated renal elimination.

Wang L1, Pan X, Sweet DH.
Biochemical pharmacology.Biochem Pharmacol.2013 Oct 1;86(7):991-6. doi: 10.1016/j.bcp.2013.08.016. Epub 2013 Aug 22.
Rhein, a major metabolite of the prodrug diacerein and a major component of the medicinal herb Rheum sp., is used for its beneficial effects in a variety of clinical applications including the treatment of osteoarthritis and diabetic nephropathy. The physicochemical properties of rhein are consisten
PMID 23973525

Type 1 sodium-dependent phosphate transporter acts as a membrane potential-driven urate exporter.

Miyaji T1, Kawasaki T, Togawa N, Omote H, Moriyama Y.
Current molecular pharmacology.Curr Mol Pharmacol.2013 Jul;6(2):88-94.
SLC17A1 protein (NPT1) was the first identified member of the SLC17 phosphate transporter family, and is known to mediate Na(+)/inorganic phosphate (Pi) co-transport when expressed in Xenopus oocytes. Although this protein was suggested to be a renal polyspecific anion exporter, its transport proper
PMID 23876149

関根孝司
日本薬理学雑誌 117(3), 177-186, 2001-03-01
薬物トランスポーターは薬物の吸収·分布·排泄に関与し, 薬物代謝酵素と並び薬物の体内動態を決定する重要な因子である.アニオン性薬物および薬物代謝物の輸送を担う有機アニオントランスポーターは代表的な薬物トランスポーターであり, 腎臓および肝臓に組織特異的な有機アニオン輸送系が存在するとされてきた.我々は腎臓からのアニオン性薬物の排泄に重要な役割を担う多選択性有機アニオントランスポ …
NAID 10007365765

TANAKA Satoru,KANDA Akira,ASHIDA Shin-ichiro
The Japanese Journal of Pharmacology 54(3), 307-314, 1990
… In the conventional clearance studies in urate-loaded dogs, intravenous injection of DR-3438 (3-30 mg/kg) resulted in dose-related increases in fractional excretion of urate (FEua), urine flow and sodium excretion. … Stop-flow studies in dogs revealed that DR-3438 (30 mg/kg) blocks both urate reabsorption and p-aminohippurate secretion in the proximal segment of the nephron and strongly inhibits reabsorption of water, sodium and potassium in the distal segments. …
NAID 130000832944