mixed function oxidase

混合機能酸素添加酵素

WordNet

1. perform as expected when applied; "The washing machine wont go unless its plugged in"; "Does this old car still run well?"; "This old radio doesnt work anymore" (同)work, operate, go, run
2. (mathematics) a mathematical relation such that each element of a given set (the domain of the function) is associated with an element of another set (the range of the function) (同)mathematical function, single-valued function, map, mapping
3. a relation such that one thing is dependent on another; "height is a function of age"; "price is a function of supply and demand"
4. the actions and activities assigned to or required or expected of a person or group; "the function of a teacher"; "the government must do its part"; "play its role" (同)office, part, role
5. what something is used for; "the function of an auger is to bore holes"; "ballet is beautiful but what use is it?" (同)purpose, role, use
6. a formal or official social gathering or ceremony; "it was a black-tie function"
7. combine (electronic signals); "mixing sounds"
8. add as an additional element or part; "mix water into the drink" (同)mix in
9. the act of mixing together; "paste made by a mix of flour and water"; "the mixing of sound channels in the recording studio" (同)commixture, admixture, mixture, intermixture, mixing
10. an event that combines things in a mixture; "a gradual mixture of cultures" (同)mixture
11. a commercially prepared mixture of dry ingredients (同)premix
12. to bring or combine together or with something else; "resourcefully he mingled music and dance" (同)mingle, commix, unify, amalgamate
13. performing or able to perform its regular function; "a functioning flashlight"
14. any of the enzymes that catalyze biological oxidation

PrepTutorEJDIC

1. (人・物の果たすべき)『働き』,機能,役目;《しばしば複数形で》職務 / (公式の)儀式,《話》大きな催し(集まり),式典 / (数学で)関数 / 〈機械などが〉『機能を果たす』,動く / (…の)役目をする,代用となる《+『as』+『名』》
2. 〈複数のもの〉‘を'『混ぜ合わせる』,混合する,混同する / …‘を'混ぜ合わせて作る,調合して作る / …‘を'寄せ集める,まとめる / 〈物が〉(…と)混ざる,混合する《+『with』+『名』》 / 〈人が〉(他の人と)交わる,交際する《+『with』+『名』》 / 〈C〉〈U〉混合 / 〈C〉混合物(食品,薬) / 〈C〉〈U〉(水・火を加えて即席にでき上がる)素(もと),ミックス
3. (異なった成分(要素)のものが)混ざった,混合の,混成の / 男女混合の / 人種(宗教・国籍など)が違う人々の(から成る)

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/02/05 01:25:51」(JST)

wiki en

[Wiki en表示]

Mixed-function oxidase is the name of a family of oxidase enzymes that catalyze a reaction in which each of the two atoms of oxygen in O₂ is used for a different function in the reaction.

Oxidase is a general name for enzymes that catalyze oxidations in which molecular oxygen is the electron acceptor but oxygen atoms do not appear in the oxidized product. Often, oxygen is reduced to either water (cytochrome oxidase of the mitochondrial electron transfer chain) or hydrogen peroxide (dehydrogenation of fatty acyl-CoA in peroxisomes). Most of the oxidases are flavoproteins.

The name "mixed-function oxidase" indicates that the enzyme oxidizes two different substrate simultaneously. Desaturation of fatty acyl-CoA in vertebrates is an example of the mixed-function oxidase reaction. In the process, saturated fatty acyl-CoA and NADPH are oxidized by molecular oxygen (O₂) to produce monounsaturated fatty acyl-CoA, NADP⁺ and 2 molecules of water.

Reaction

The mixed-function oxidase reaction proceeds as follows:

AH + BH₂ + O₂ --> AOH + B + H₂O h2o as catalyst

References

UpToDate Contents

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• 1. 慢性肉芽腫性疾患：病因、臨床症状、および診断 chronic granulomatous disease pathogenesis clinical manifestations and diagnosis
• 2. 肝臓の有機アニオン輸送能および薬物代謝能の検査 tests of the livers capacity to transport organic anions and metabolize drugs
• 3. 新生児における筋緊張低下を引き起こす末梢神経および筋肉の障害に関する概要 overview of peripheral nerve and muscle disorders causing hypotonia in the newborn
• 4. 膵外分泌機能検査 pancreatic exocrine function tests
• 5. 成人における双極性障害：急性躁病、 混合性エピソード、および軽躁に対する薬物療法 bipolar disorder in adults pharmacotherapy for acute mania mixed episodes and hypomania

English Journal

• Haem oxygenase-1 counteracts the effects of interleukin-1β on inflammatory and senescence markers in cartilage-subchondral bone explants from osteoarthritic patients.

• Clérigues V, Guillén MI, Gomar F, Alcaraz MJ.SourceDepartment of Pharmacology, University of Valencia, and IDM, Av. Vicent A. Estellés s/n, 46100 Burjasot, Valencia, Spain.
• Clinical science (London, England : 1979).Clin Sci (Lond).2012 Mar 1;122(5):239-50.
• IL (interleukin)-1β plays an important role in cartilage extracellular matrix degradation and bone resorption in OA (osteoarthritis) through the induction of degradative enzymes and pro-inflammatory mediators. In the present study, we have determined the consequences of HO-1 (haem oxygenase-1) indu
• PMID 21954917

• Detection of mutagens and BaPMO inducers in river water using the Blue Cotton adsorption technique.

• Britvić S, Hackenberger BK, Jarić D, Stepić S.SourceCenter for Marine and Environmental Research, Rudjer Boskovic Institute, Zagreb, Croatia.
• Environmental toxicology.Environ Toxicol.2012 Mar;27(3):146-54. doi: 10.1002/tox.20625. Epub 2010 Jun 1.
• Induction of Mixed Function Oxidase (MFO) activity and bioactivation potential were measured in experimental carp and in native fish species from two rivers with different pollution level (Sava and Mrežnica). The experimental carp were intraperitoneally exposed to various water volume equivalents o
• PMID 20549646

Japanese Journal

• Canine neutrophil dysfunction caused by downregulation of β2-integrin expression without mutation

• Kobayashi Saori,Sato Reeko,Abe Yuya,Inanami Osamu,Yasui Hironobu,Omoe Ktsuhiko,Yasuda Jun,Hankanga Careen,Oda Shinichi,Sasaki Juso
• Veterinary Immunology and Immunopathology 130(3-4), 187-196, 2009
• … We report clinical features and analysis of neutrophil function from two mixed-breed canine littermates (one female and one male dog) similar to CLAD. … Neutrophil function tests revealed a marked reduction of serum-opsonized zymosan-mediated superoxide production in the two littermates. …
• NAID 120001700548

• 3P107 部分還元型ウシ心筋チトクロム酸化酵素のX線構造解析(ヘム蛋白質、電子状態、蛋白質(構造・構造機能相関),口頭発表,第45回日本生物物理学会年会)

• 谷口 槙,村本 和優,伊藤-新沢 恭子,前田 友子,山下 栄樹,月原 冨武,吉川 信也
• 生物物理 47(SUPPLEMENT_1), S229, 2007-11-20
• NAID 110006562864

Related Links

• Mixed-function oxidase - Wikipedia, the free encyclopedia

Mixed-function oxidase is the name of a family of oxidase enzymes that catalyze a reaction in which each of the two atoms of oxygen in O2 is used for a different function in the reaction. Oxidase is a general name for enzymes that catalyze ...

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★リンクテーブル★

リンク元	「モノオキシゲナーゼ」「混合機能オキシダーゼ」
拡張検索	「mixed-function oxidases」「cytochrome P-450 linked mixed function oxidase」
関連記事	「function」「mix」「mixed」

「モノオキシゲナーゼ」

　　[★]

英

monooxygenase

同

一原子酸素添加酵素、混合機能オキシダーゼ mixed function oxidase

関

シトクロムP450 cytochrome P450

「混合機能オキシダーゼ」

　　[★]

英

mixed function oxidase

モノオキシゲナーゼ

「mixed-function oxidases」

　　[★]

関

See also Cytochrome P450 system

「cytochrome P-450 linked mixed function oxidase」

　　[★] シトクロムP-450酵素系

「function」

　　[★]

• n.

• 機能、(数学)関数、(化学)官能基

survival as a function of HbA1c in people with type 2 diabetes HbA1cの機能を考慮（指標に）した2型糖尿病の患者の生存（予後）

Figure 2A shows survival as a function of device removal during index hpspitalization, censored at 1 year or date of last contact. (Figure2Aはは最初の入院中における心臓デバイス除去に関する生存曲線で退院後1年もしくは最後の接触で打ち切っている)

• v.

• 機能する

関

functional、functional group、functionalise、functionalize、operate

　 　 　 　 　 　 　

「mix」

　　[★]

• 混合、混合する、混ぜる

関

admix、admixture、blend、intermingle、merge、mixture、scramble、shuffle、shuffling

　 　 　 　 　 　 　

「mixed」

　　[★]

• 混合性の

関

combined