late asthmatic response

遅発型喘息反応 LAR

WordNet

1. of a later stage in the development of a language or literature; used especially of dead languages; "Late Greek"
2. later than usual or than expected; "the train arrived late"; "we awoke late"; "the children came late to school"; "notice came so tardily that we almost missed the deadline"; "I belatedly wished her a happy birthday" (同)belatedly, tardily
3. at or toward an end or late period or stage of development; "the late phase of feudalism"; "a later symptom of the disease"; "later medical science could have saved the child" (同)later
4. of the immediate past or just previous to the present time; "a late development"; "their late quarrel"; "his recent trip to Africa"; "in recent months"; "a recent issue of the journal" (同)recent
5. at an advanced age or stage; "she married late"; "undertook the project late in her career"
6. being or occurring at an advanced period of time or after a usual or expected time; "late evening"; "late 18th century"; "a late movie"; "took a late flight"; "had a late breakfast"
7. having died recently; "her late husband"
8. a result; "this situation developed in response to events in Africa"
9. a phrase recited or sung by the congregation following a versicle by the priest or minister
10. the manner in which an electrical or mechanical device responds to an input signal or a range of input signals
11. relating to breathing with a whistling sound (同)wheezing, wheezy
12. a person suffering from asthma; "she is a chronic asthmatic"; "the painful gasps of a dying asthmatic"
13. the syllable naming the sixth (submediant) note of a major or minor scale in solmization (同)lah

PrepTutorEJDIC

1. (定刻・通常・予定の時間より)『遅れた』,遅い / (時刻が)『遅い』,遅く始まる,遅くまで続く;夜更けの / (時期が)『遅い』,終りごろの,後期の / 『最近の』,最新の(recent) / 《the~,one's~》『前の』,先の,前任の(former) / 《the~,one's~》『故』…,つい先ごろ死んだ / (定刻などより)『遅れて』,遅く / (時刻が)『遅く』,遅くまで,(特に)夜更けに;(時期が)遅く,終りごろに / 『最近』,近ごろ(recently)
2. 〈C〉(…に対する)『返事』,『返答』《+『to』+『名』》 / 〈C〉〈U〉(…に対する)『反応』,『反響』《『to』+『名』》 / 〈C〉応答歌,応唱(牧師にならって合唱隊・会衆が短い祈り・歌を応答すること)
3. 喘息の / 喘息患者
4. ラ(全音階の第6音)

UpToDate Contents

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English Journal

• Allergen-induced asthmatic responses modified by a GATA3-specific DNAzyme.

• Krug N1, Hohlfeld JM, Kirsten AM, Kornmann O, Beeh KM, Kappeler D, Korn S, Ignatenko S, Timmer W, Rogon C, Zeitvogel J, Zhang N, Bille J, Homburg U, Turowska A, Bachert C, Werfel T, Buhl R, Renz J, Garn H, Renz H.
• The New England journal of medicine.N Engl J Med.2015 May 21;372(21):1987-95. doi: 10.1056/NEJMoa1411776. Epub 2015 May 17.
• BACKGROUND: The most prevalent phenotype of asthma is characterized by eosinophil-dominated inflammation that is driven by a type 2 helper T cell (Th2). Therapeutic targeting of GATA3, an important transcription factor of the Th2 pathway, may be beneficial. We evaluated the safety and efficacy of SB
• PMID 25981191

• LPS exacerbates functional and inflammatory responses to ovalbumin and decreases sensitivity to inhaled fluticasone propionate in a guinea pig model of asthma.

• Lowe AP1, Thomas RS, Nials AT, Kidd EJ, Broadley KJ, Ford WR.
• British journal of pharmacology.Br J Pharmacol.2015 May;172(10):2588-603. doi: 10.1111/bph.13080. Epub 2015 Mar 24.
• BACKGROUND AND PURPOSE: Asthma exacerbations contribute to corticosteroid insensitivity. LPS is ubiquitous in the environment. It causes bronchoconstriction and airway inflammation and may therefore exacerbate allergen responses. This study examined whether LPS and ovalbumin co-administration could
• PMID 25586266

• Pulmonary edema measured by MRI correlates with late-phase response to allergen challenge.

• Evans RL1, Changani KK, Hotee S, Pindoria K, Campbell S, Nials AT, Ford WR, Broadley KJ, Kidd EJ.
• Experimental lung research.Exp Lung Res.2015 May;41(4):189-98. doi: 10.3109/01902148.2014.985407. Epub 2015 Apr 6.
• PURPOSE: Asthma is associated with reversible airway obstruction, leucocyte infiltration, airways hyperresponsiveness (AHR), and airways remodeling. Fluid accumulation causes pulmonary edema contributing to airways obstruction. We examined the temporal relationship between the late asthmatic respons
• PMID 25844692

Japanese Journal

• Complete Dependence on CD4^+ Cells in Late Asthmatic Response, but Limited Contribution of the Cells to Airway Remodeling in Sensitized Mice

• Nabe Takeshi,Morishita Toyoko,Matsuya Kouki [他],IKEDO Ayumu,FUJII Masanori,MIZUTANI Nobuaki,YOSHINO Shin
• Journal of pharmacological sciences 116(4), 373-383, 2011-08-20
• … It is known that the late asthmatic response (LAR), a characteristic feature of asthma, is closely associated with CD4<SUP>+</SUP> … The late phase increase in airway resistance after the 4th challenge was also completely inhibited by anti-CD4 mAb. …
• NAID 10029895650

• Intratracheal Sensitization/Challenge-Induced Biphasic Asthmatic Response and Airway Hyperresponsiveness in Guinea Pigs

• Mizutani Nobuaki,Inui Shouichi,Yoshino Shin [他],Nabe Takeshi
• Biological and Pharmaceutical Bulletin 33(12), 1949-1952, 2010
• … In the present study, we attempted to create an animal model of asthma showing a biphasic asthmatic response and airway hyperresponsiveness, in which the allergic responses are restricted to the lung. … Pranlukast, theophylline, and dexamethasone suppressed the late asthmatic response and airway hyperresponsiveness. … The early asthmatic response was inhibited by theophylline and dexamethasone. …
• NAID 130000402324

• Effects of Hydroxy Pentacyclic Triterpene Acids from Forsythia viridissima on Asthmatic Responses to Ovalbumin Challenge in Conscious Guinea Pigs

• Lee Ji Yun,Moon Hee,Kim Chang Jong
• Biological and Pharmaceutical Bulletin 33(2), 230-237, 2010
• … ti-inflammatory ingredients from Forsythiae fructus (FF), we isolated three hydroxyl pentacyclic triterpene acids (HTAs), namely, oleanolic acid, ursolic acid, and betulinic acid, from an ethylacetate fraction of FF, and evaluated the effect of these triterpene acids on asthmatic guinea pigs by measuring specific airway resistance (sRaw) during both immediate-phase response (IAR) and late-phase response (LAR) following ovalbumin challenge using a double-chambered plethysmograph. …
• NAID 130000156629

Related Links

• Allergy - Wikipedia, the free encyclopedia

Cytokines from mast cells may play a role in the persistence of long-term effects. Late-phase responses seen in asthma are slightly different from those seen in other allergic responses, although they are still caused by release of mediators ...

• Early Onset And Late Onset Asthma | Detailed Information On ...

This is called is called the early asthma response. But in almost 40% of the cases wheezing develops after three to four hours after the inhalation, peaks in four to eight hours, and may last for twenty-four hours. This is called the late asthma ...

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★リンクテーブル★

リンク元	「LAR」「気管支喘息遅発型反応」「遅発型喘息反応」
関連記事	「late」「response」「asthmatic」「late asthmatic」

「LAR」

　　[★]

• 生涯寄与リスク lifetime attributable risk
• 低位前方切除術 low anterior resection
• 遅発型喘息反応 late asthmatic response

「気管支喘息遅発型反応」

　　[★]

英

late phase asthmatic reaction？

関

気管支喘息、遅発性喘息 LAR、遅発型喘息反応 late asthmatic response

「遅発型喘息反応」

　　[★]

英

late asthmatic response LAR

関

好中球遊走因子

「late」

　　[★]

• adv.

• (比較級later-最上級latest)遅い、遅発の、遅発型の、晩発の、後の、後期の

関

after、afterward、afterwards、anaphase、behind、delayed、following、late-stage、post、posterior、slow、subsequent

　 　 　 　 　 　 　 　

「response」

　　[★]

• n.

• 返答、応答
• 反応、感応、反響。(刺激に対する)反応

　 　 　 　

「asthmatic」

　　[★]

• adj.

• 喘息の、喘息性の

• n.

• 喘息患者

関

asthma

　 　 　

「late asthmatic」

　　[★]

• 遅発型喘息の

関

late asthma