WordNet

the innermost membrane of an organ (especially the inner lining of an artery or vein or lymphatic vessel)
of or relating to the intima
the basic unit of money in Peru

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/05/31 09:48:24」(JST)

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The tunica intima (New Latin "inner coat"), or intima for short, is the innermost tunica (layer) of an artery or vein. It is made up of one layer of endothelial cells and is supported by an internal elastic lamina. The endothelial cells are in direct contact with the blood flow.

The tunicae of blood vessels are three layers — an inner layer (the tunica intima), a middle layer (the tunica media), and an outer layer (the tunica adventitia).

In dissection, the inner coat (tunica intima) can be separated from the middle (tunica media) by a little maceration, or it may be stripped off in small pieces; but, because of its friability, it cannot be separated as a complete membrane. It is a fine, transparent, colorless structure which is highly elastic, and, after death, is commonly corrugated into longitudinal wrinkles.

The inner coat consists of:

A layer of pavement endothelium, the cells of which are polygonal, oval, or fusiform, and have very distinct round or oval nuclei. This endothelium is brought into view most distinctly by staining with silver nitrate.
A subendothelial layer, consisting of delicate connective tissue with branched cells lying in the interspaces of the tissue; in arteries of less than 2 mm in diameter the subendothelial layer consists of a single stratum of stellate cells, and the connective tissue is only largely developed in vessels of a considerable size.
An elastic or fenestrated layer, which consists of a membrane containing a net-work of elastic fibers, having principally a longitudinal direction, and in which, under the microscope, small elongated apertures or perforations may be seen, giving it a fenestrated appearance. It was therefore called by Henle the fenestrated membrane. This membrane forms the chief thickness of the inner coat, and can be separated into several layers, some of which present the appearance of a network of longitudinal elastic fibers, and others a more membranous character, marked by pale lines having a longitudinal direction. In minute arteries the fenestrated membrane is a very thin layer; but in the larger arteries, and especially in the aorta, it has a considerable thickness.

Additional images

Vein
Microphotography of arterial wall with calcified (violet colour) atherosclerotic plaque (haematoxillin and eosin stain)

References

This article incorporates text in the public domain from the 20th edition of Gray's Anatomy (1918)

External links

Histology image: 66_02 at the University of Oklahoma Health Sciences Center - "Aorta"
Anatomy photo: Circulatory/vessels/vessels7/vessels2 - Comparative Organology at University of California, Davis — "Bird, vessels (LM, High)"
Image at About.com

UpToDate Contents

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English Journal

Short telomere length is associated with arterial aging in patients with type 2 diabetes mellitus.

Dudinskaya EN1, Tkacheva ON2, Shestakova MV2, Brailova NV2, Strazhesko ID2, Akasheva DU2, Isaykina OY2, Sharashkina NV2, Kashtanova DA2, Boytsov SA2.
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It is known that glucose disturbances contribute to micro- and macrovascular complications and vascular aging. Telomere length is considered to be a cellular aging biomarker. It is important to determine the telomere length role in vascular structural and functional changes in patients with diabetes
PMID 26034119

Layer-dependent wall properties of abdominal aortic aneurysms: Experimental study and material characterization.

Sassani SG1, Kakisis J2, Tsangaris S3, Sokolis DP4.
Journal of the mechanical behavior of biomedical materials.J Mech Behav Biomed Mater.2015 Sep;49:141-61. doi: 10.1016/j.jmbbm.2015.04.027. Epub 2015 May 8.
Mechanical testing and in-depth characterization of the abdominal aortic aneurysm wall from fifteen patients undergoing open surgery was performed to establish the layer-dependent tissue properties that are non-available in the literature. Quantitative microscopic evaluation was performed to identif
PMID 26011656

Growth differentiation factor-15 in children and adolescents with thalassemia intermedia: Relation to subclinical atherosclerosis and pulmonary vasculopathy.

Tantawy AA1, Adly AA2, Ismail EA3, Youssef OI2, Ali ME2.
Blood cells, molecules & diseases.Blood Cells Mol Dis.2015 Aug;55(2):144-50. doi: 10.1016/j.bcmd.2015.06.001. Epub 2015 Jun 6.
BACKGROUND: Heart disease is the leading cause of mortality and one of the main causes of morbidity in β-thalassemia. Growth differentiation factor-15 (GDF-15), a member of the transforming growth factor-β superfamily, is a marker of ineffective erythropoiesis in several anemias.AIM: To determine
PMID 26142330

Japanese Journal

アレッサンドロ・ヴェッリと感情の価値

菅野類
イタリア学会誌 (61), 147-171, 2011-10-15
… Tuttavia, la maturita intellettuale di Pietro contribui fortemente a orientare la presa di posizione del fratello minore, a dispetto della sua intima natura. …
NAID 110008750040

Elevated serum retinol-binding protein 4 concentrations are associated with chronic kidney disease but not with the higher carotid intima-media thickness in type 2 diabetic subjects

CHU Chih-Hsun,LAM Hing-Chung,LEE Jenn-Kuen,LU Chih-Chen,SUN Chun-Chin,CHENG Hsin-Ju,WANG Mei-Chun,CHUANG Ming-Ju
Endocrine journal 58(10), 841-847, 2011-10-01
NAID 10029863014

Related Pictures

★リンクテーブル★

リンク元	「内膜」「intimal」「endomembrane」
拡張検索	「intimately」「vascular intima」「neointimal thickening」

「内膜」

Tunica intima
	Transverse section through a small artery and vein of the mucous membrane of the epiglottis of a child. (Tunica intima is at "e")
Details
Identifiers
Latin	Tunica intima
MeSH	A07.231.330.800
Code	TH H3.09.02.0.01003
TA	A12.0.00.018
FMA	55589
	Anatomical terminology [edit on Wikidata]