WordNet

of or relating to the intima
any of a variety of loose fitting cloaks extending to the hips or knees
an enveloping or covering membrane or layer of body tissue (同)tunica, adventitia
the innermost membrane of an organ (especially the inner lining of an artery or vein or lymphatic vessel)
the basic unit of money in Peru

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チュニカ(古代ギリシア・ローマで男女が用いたひざまである半そでまたはそでなしの上着) / (ゆったりしたそでなしの)チューニック(婦人用スポーツ服,女子学生の制服などに用いる) / 《英》軍人・警官などが制服として着る一種の上着

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2017/11/17 04:59:14」(JST)

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The tunica intima (New Latin "inner coat"), or intima for short, is the innermost tunica (layer) of an artery or vein. It is made up of one layer of endothelial cells and is supported by an internal elastic lamina. The endothelial cells are in direct contact with the blood flow.

The tunicae of blood vessels are three layers—an inner layer (the tunica intima), a middle layer (the tunica media), and an outer layer (the tunica adventitia).

In dissection, the inner coat (tunica intima) can be separated from the middle (tunica media) by a little maceration, or it may be stripped off in small pieces; but, because of its friability, it cannot be separated as a complete membrane. It is a fine, transparent, colorless structure which is highly elastic, and, after death, is commonly corrugated into longitudinal wrinkles.

The inner coat consists of:

A layer of pavement endothelium, the cells of which are polygonal, oval, or fusiform, and have very distinct round or oval nuclei. This endothelium is brought into view most distinctly by staining with silver nitrate.
A subendothelial layer, consisting of delicate connective tissue with branched cells lying in the interspaces of the tissue; in arteries of less than 2 mm in diameter the subendothelial layer consists of a single stratum of stellate cells, and the connective tissue is only largely developed in vessels of a considerable size.^{[citation needed]}
An elastic or fenestrated layer, which consists of a membrane containing a net-work of elastic fibers, having principally a longitudinal direction, and in which, under the microscope, small elongated apertures or perforations may be seen, giving it a fenestrated appearance. It was therefore called by Henle the fenestrated membrane. This membrane forms the chief thickness of the inner coat, and can be separated into several layers, some of which present the appearance of a network of longitudinal elastic fibers, and others a more membranous character, marked by pale lines having a longitudinal direction. In minute arteries the fenestrated membrane is a very thin layer; but in the larger arteries, and especially in the aorta, it has a considerable thickness.

Additional images

Vein
Microphotography of arterial wall with calcified (violet colour) atherosclerotic plaque (haematoxillin and eosin stain)

References

This article incorporates text in the public domain from the 20th edition of Gray's Anatomy (1918)

External links

Histology image: 66_02 at the University of Oklahoma Health Sciences Center - "Aorta"
Anatomy photo: Circulatory/vessels/vessels7/vessels2 - Comparative Organology at University of California, Davis — "Bird, vessels (LM, High)"
Image at About.com

UpToDate Contents

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English Journal

Transplantation of VEGFl65-overexpressing vascular endothelial progenitor cells relieves endothelial injury after deep vein thrombectomy.

Tang JJ1, Meng QY2, Cai ZX3, Li XQ4.
Thrombosis research.Thromb Res.2016 Jan;137:41-5. doi: 10.1016/j.thromres.2015.11.025. Epub 2015 Nov 26.
AIM: The purpose of this study was to explore the therapeutic efficacy of VEGF165-overexpressing vascular endothelial progenitor cells (EPCs) in post-thrombotic syndrome.MATERIALS AND METHODS: A thrombus model was developed to mimic the in-vivo setting, and adenovirus transfection was used to overex
PMID 26632512

Identification of gene variants related to the nitric oxide pathway in patients with acute coronary syndrome.

Umman B1, Cakmakoglu B2, Cincin ZB2, Kocaaga M1, Emet S1, Tamer S3, Gokkusu C4.
Gene.Gene.2015 Dec 10;574(1):76-81. doi: 10.1016/j.gene.2015.07.081. Epub 2015 Jul 30.
Dysfunction of vascular endothelium is known to have an essential role in the atherosclerotic process by releasing mediators including nitric oxide (NO). Nitric oxide maintains endothelial balance by controlling cellular processes of vascular smooth muscle cells. Evidence suggests that variations in
PMID 26232608

High hydrostatic pressure upon the vasa vasorum of the greater saphenous and splenic vein walls: a comparative study.

Tao W1, Wei H, Rui X, Xiaoji Z, Haibo C, Lingyan J, Meihong W, Yongbo X.
International angiology : a journal of the International Union of Angiology.Int Angiol.2015 Dec;34(6):568-75. Epub 2015 Feb 25.
AIMS: Hypoxia and high hydrostatic pressure can induce an increase in the thickness of the tunica media and intima; secondary vasa vasorum (VV) increase to fit the remodeling of the vessel wall. We aimed to investigate the impact of high hydrostatic pressure on VV in the varicose greater saphenous v
PMID 25714228

Japanese Journal

Pressure Controlled Clamp Using Shape Memory Alloy for Minimal Vessel Invasion in Blood Flow Occlusion

Zhang Ye,Kanetaka Hiroyasu,Sano Yuya,Kano Mitsuhiro,Kudo Tadaaki,Sato Takumi,Shimizu Yoshinaka
Annals of Thoracic and Cardiovascular Surgery 19(1), 35-42, 2013
… Histological section in the experimental group showed no obvious except a slight compressive damage in the tunica intima. …
NAID 130002148300

側副血行路に発生した肝仮性動脈瘤の1例

坂口達馬,海堀昌樹,石崎守彦 [他],松井康輔,松島英之,沖田美香,長尾泰孝,權雅憲
肝臓 53(9), 570-574, 2012-09-25
肝動脈瘤は，画像診断の進歩により発見例が増加している．破裂例は致死率が高く，未破裂例の取り扱いが問題になる．今回，肝内側副血行路上に発生した仮性動脈瘤の1例を経験した．症例は67歳，男性．38歳時，胆嚢摘出術の既往あり．45歳時よりHCV抗体陽性のため近医で経過観察中であったが，USで肝腫瘤を指摘され当科紹介された．Dynamic CTで肝門部に接し動脈と等濃度で造影される結節像を認め，肝動脈瘤と …
NAID 10031039200

Thoracic Endovascular Aortic Repair with Debranching after Celiac Axis Coil Embolization for Thoracoabdominal Aortic Aneurysms

上田秀保,大竹裕志,西田佑児,村杉桂子,眞田順一郎,渡邊剛
日本血管外科学会雑誌 21(7), 769-772, 2012
… Matsui-Kitamura (MK) stent-graft was used for protection of distal tunica intima. …
NAID 130004490444

Related Pictures

Muscular Arteries: Tunica Intima startpage Tunica intima | anatomy | Britannica.com Blood Vessels Flashcards - Chapter 19 - The three types of blood vessels that transport blood Tunica Media; Vascular Media Vascular tunics – Veterinary Histology

★リンクテーブル★

リンク元	「内膜」「intimal」「endomembrane」「arterial intima」「vascular intima」

「内膜」

Tunica intima
	Transverse section through a small artery and vein of the mucous membrane of the epiglottis of a child. (Tunica intima is at "e")
Details
Identifiers
Latin	Tunica intima
MeSH	A07.231.330.800
Code	TH H3.09.02.0.01003
TA	A12.0.00.018
TH	H3.09.02.0.01003
FMA	55589
	Anatomical terminology [edit on Wikidata]