インターフェロン活性化遺伝子ファクター3
- 関
- ISGF3
WordNet
- be a contributing factor; "make things factor into a companys profitability"
- any of the numbers (or symbols) that form a product when multiplied together
- an independent variable in statistics
- anything that contributes causally to a result; "a number of factors determined the outcome"
- consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
- resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
- an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"
- a concept whose truth can be proved; "scientific hypotheses are not facts"
- a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"
- a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"
- stir the feelings, emotions, or peace of; "These stories shook the community"; "the civil war shook the country" (同)shake, shake up, excite, stir
- cause to be alert and energetic; "Coffee and tea stimulate me"; "This herbal infusion doesnt stimulate" (同)arouse, brace, energize, energise, perk_up
- act as a stimulant; "The book stimulated her imagination"; "This play stimulates" (同)excite
- stir feelings in; "stimulate my appetite"; "excite the audience"; "stir emotions" (同)excite, stir
- (genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors" (同)cistron, factor
- an antiviral protein produced by cells that have been invaded by a virus; inhibits replication of the virus
PrepTutorEJDIC
- (…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize
- 〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行
- …を『刺激する』,励ます,元気づける / 刺激[剤]となる
- 遺伝子
- インターフェロン(ウイルス増殖抑制物質)
UpToDate Contents
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English Journal
- Immunohistochemical analysis of the expression of cellular transcription NFκB (p65), AP-1 (c-Fos and c-Jun), and JAK/STAT in leprosy.
- Silva LM1, Hirai KE1, de Sousa JR2, de Souza J1, Fuzii HT2, Dias LB Jr1, Carneiro FR1, de Souza Aarão TL1, Quaresma JA3.
- Human pathology.Hum Pathol.2015 May;46(5):746-52. doi: 10.1016/j.humpath.2015.01.015. Epub 2015 Feb 12.
- Leprosy is a disease whose clinical spectrum depends on the cytokine patterns produced during the early stages of the immune response. The main objective of this study was to describe the activation pattern of cellular transcription factors and to correlate these factors with the clinical forms of l
- PMID 25771902
- Lipoprotein in the cell wall of Staphylococcus aureus is a major inducer of nitric oxide production in murine macrophages.
- Kim NJ1, Ahn KB1, Jeon JH2, Yun CH3, Finlay BB4, Han SH5.
- Molecular immunology.Mol Immunol.2015 May;65(1):17-24. doi: 10.1016/j.molimm.2014.12.016. Epub 2015 Jan 16.
- Staphylococcus aureus is a Gram-positive bacterium that causes inflammation at infection sites by inducing various inflammatory mediators such as nitric oxide (NO). To identify the staphylococcal virulence factors contributing to NO production, we compared the ability of ethanol-killed wild-type S.
- PMID 25600878
- Molecular characterization of RIG-I, STAT-1 and IFN-beta in the horseshoe bat.
- Li J1, Zhang G1, Cheng D1, Ren H1, Qian M1, Du B2.
- Gene.Gene.2015 Apr 25;561(1):115-23. doi: 10.1016/j.gene.2015.02.013. Epub 2015 Feb 10.
- Wild Chinese horseshoe bats have been proven to be natural reservoirs of SARS-like coronaviruses. However, the molecular characterization of key proteins in bats still needs to be explored further. In this study, we used cloning and bioinformatics to analyze the sequence of RIG-I, STAT-1 and IFN-β
- PMID 25680291
Japanese Journal
- Anti-hepatitis C virus activity of geranylgeranylacetone treatment in hepatitis C-infected patients
- Yamaguchi Tohei,Ichikawa Tatsuki,Takeshita Shigeyuki,Taura Naota,Miyaaki Hisamitsu,Muraoka Toru,Shibata Hidetaka,Honda Takuya,Hamasaki Keisuke,Kato Yuji,Takeshima Fuminao,Nakao Kazuhiko
- Acta Medica Nagasakiensia 57(1), 1-4, 2012-04-00
- … GGA induces antiviral gene expression by stimulating the formation of interferon-stimulated gene factor 3 in humanhepatoma cells. … In the future, it will be necessary to examinethe clinical effectiveness of the combination of treatment with both GGA and interferon in HCV patients. …
- NAID 110009226235
- Regulation of the Nuclear Factor (NF)-κB Pathway by ISGylation(Molecular and Cell Biology)
- Minakawa Miki,Sone Takayuki,Takeuchi Tomoharu [他],YOKOSAWA Hideyoshi
- Biological & pharmaceutical bulletin 31(12), 2223-2227, 2008-12-01
- … Post-translational modification with ISG15 (interferon-stimulated gene 15kDa) (ISGylation) is mediated by a sequential reaction similar to ubiquitination, and various target proteins for ISGylation have been identified. … Ubc13 forms a heterodimer with Uev1A, a ubiquitin-conjugating enzyme variant, and the Ubc13-Uev1A complex catalyzes the assembly of a Lys63-linked polyubiquitin chain, which plays a non-proteolytic role in the nuclear factor (NF)-κB pathway. …
- NAID 110007005019
- Development of Interferon-α Resistant Subline from Human Chronic Myelogenous Leukemia Cell Line KT-1
- Yamauchi Hayato,Sakai Ikuya,Narumi Hirosi [他],TAKEUCHI Kazuto,SOGA Shinji,FUJITA Shigeru
- Internal medicine 40(7), 607-612, 2001-07-00
- … Objective Interferon-alpha (IFN-α) is one of the most effective therapeutic agents for a number of hematological malignancies, including chronic myelogenous leukemia (CML). …
- NAID 130000767677
Related Links
- They are typically divided among three IFN classes: Type I IFN, Type II IFN, and Type III IFN. .... As a result, an IFN-stimulated gene factor 3 (ISGF3) complex forms—this contains STAT1, STAT2 and a third transcription factor called IRF9— and moves into the cell nucleus. Inside the nucleus ... The ability of interferon to induce protein production from interferon stimulated genes (ISGs) can also be affected.
- erates through interferon-stimulated-gene factor 3 (ISGF), a transcription factor two components ofwhich are members of the newly characterized Stat family of transcription factors. Interferon a induces tyrosine phosphorylation of Statl and ...
★リンクテーブル★
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- 関
- interferon-stimulated gene factor 3
- 同
- interferon-stimulated gamma factor 3
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- 英
- interferon-stimulated gene factor 3、ISGF3
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インターフェロン活性化遺伝子ファクター3αサブユニット
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インターフェロン活性化遺伝子ファクター3γサブユニット
[★]
- 関
- actual、actually、in fact、in practice、indeed、practically
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- 関
- element、elementary、factorial、parameter
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- 関
- incite、irritate、prime、stimulation、stimuli、stimulus
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インターフェロン