- 関
- anti-oncogene、antioncogene、cancer suppressor gene、metastasis suppressor gene、recessive oncogene、tumor suppressor gene
WordNet
- cultivate by growing, often involving improvements by means of agricultural techniques; "The Bordeaux region produces great red wines"; "They produce good ham in Parma"; "We grow wheat here"; "We raise hogs here" (同)raise, farm, produce
- come to have or undergo a change of (physical features and attributes); "He grew a beard"; "The patient developed abdominal pains"; "I got funny spots all over my body"; "Well-developed breasts" (同)develop, produce, get, acquire
- become attached by or as if by the process of growth; "The tree trunks had grown together"
- become larger, greater, or bigger; expand or gain; "The problem grew too large for me"; "Her business grew fast"
- cause to grow or develop; "He grows vegetables in his backyard"
- increase in size by natural process; "Corn doesnt grow here"; "In these forests, mushrooms grow under the trees"; "her hair doesnt grow much anymore"
- (biology) the process of an individual organism growing organically; a purely biological unfolding of events involved in an organism changing gradually from a simple to a more complex level; "he proposed an indicator of osseous development in children" (同)growing, maturation, development, ontogeny, ontogenesis
- (pathology) an abnormal proliferation of tissue (as in a tumor)
- a progression from simpler to more complex forms; "the growth of culture"
- something grown or growing; "a growth of hair"
- vegetation that has grown; "a growth of trees"; "the only growth was some salt grass"
- to put down by force or authority; "suppress a nascent uprising"; "stamp down on littering"; "conquer ones desires" (同)stamp down, inhibit, subdue, conquer, curb
- reduce the incidence or severity of or stop; "suppress a yawn"; "this drug can suppress the hemorrhage"
- put out of ones consciousness (同)repress
- an electrical device for suppressing unwanted currents (同)suppresser
- someone who suppresses; "dictators are suppressors of free speech" (同)suppresser
- a gene that suppresses the phenotypic expression of another gene (especially of a mutant gene) (同)suppresser, suppressor_gene, suppresser gene
- (genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors" (同)cistron, factor
PrepTutorEJDIC
- 『成長する』,育つ,〈植物が〉生える,茂る / (類・量・程などにおいて)『増大する』,大きくなる / 『しだいになる』 / …‘を'成長させる,大きくする,育てる / …から生じる(起こる)
- 〈U〉(…の)『成長』,発育;『発達』,発展《+『of』+『名』》 / 〈U〉(数・量,重要性・力などの)『増加』,増大,拡張《+『of』+『名』》 / 〈U〉《修飾語[句]を伴って》栽培,生産,…産 / 〈C〉成育した物,(草,木,髪,ひげなどの)生えたもの / 〈C〉腫瘍(しゅよう)
- 〈反乱など〉‘を'『鎮圧する』…,‘の'活動を押える / 〈感情・欲望など〉‘を'『抑制する』,抑える / …‘の'発表を禁止する,伏せる
- 抑圧する人,鎮圧者 / (ラジオ・テレビの)妨害電波(混信)防止装置
- 遺伝子
UpToDate Contents
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- 1. 成長ホルモンの生理学 physiology of growth hormone
- 2. 大腸癌の分子遺伝学 molecular genetics of colorectal cancer
- 3. Physiology of insulin-like growth factor 1
- 4. 前立腺癌の分子生物学 molecular biology of prostate cancer
- 5. 頭頸部の扁平上皮癌化：分子学的および遺伝学的変化 head and neck squamous cell carcinogenesis molecular and genetic alterations
English Journal
- Loss of PBRM1 expression is associated with renal cell carcinoma progression.
- Pawłowski R, Mühl SM, Sulser T, Krek W, Moch H, Schraml P.SourceInstitute of Molecular Health Sciences, ETH Zurich, Zurich, Switzerland.
- International journal of cancer. Journal international du cancer.Int J Cancer.2013 Jan 15;132(2):E11-7. doi: 10.1002/ijc.27822. Epub 2012 Oct 3.
- Although von Hippel-Lindau (VHL) tumor suppressor gene alterations dominate the genetic landscape of clear cell renal cell carcinoma (ccRCC), recent studies have identified new ccRCC genes, including SETD2, KDM6A, KDM5C, BAP1 and PBRM1. Strikingly, all these genes fall into a category of histone/chr
- PMID 22949125
- SOCS-1 gene delivery cooperates with cisplatin plus pemetrexed to exhibit preclinical antitumor activity against malignant pleural mesothelioma.
- Iwahori K, Serada S, Fujimoto M, Ripley B, Nomura S, Mizuguchi H, Shimada K, Takahashi T, Kawase I, Kishimoto T, Naka T.SourceLaboratory for Immune Signal, National Institute of Biomedical Innovation, Osaka, Japan; Department of Respiratory Medicine, Allergy, and Rheumatic Diseases, Osaka University Graduate School of Medicine, Osaka, Japan.
- International journal of cancer. Journal international du cancer.Int J Cancer.2013 Jan 15;132(2):459-71. doi: 10.1002/ijc.27611. Epub 2012 May 17.
- Malignant pleural mesothelioma (MPM) is an aggressive tumor with poor prognosis for which an effective therapy remains to be established. This study investigated the therapeutic potential of gene delivery using suppressor of cytokine signaling 1 (SOCS-1), an endogenous inhibitor of intracellular sig
- PMID 22532243
Japanese Journal
- Loss of SMAD4 From Colorectal Cancer Cells Promotes CCL15 Expression to Recruit CCR1(+) Myeloid Cells and Facilitate Liver Metastasis.
- Itatani Yoshiro,Kawada Kenji,Fujishita Teruaki,Kakizaki Fumihiko,Hirai Hideyo,Matsumoto Takuya,Iwamoto Masayoshi,Inamoto Susumu,Hatano Etsuro,Hasegawa Suguru,Maekawa Taira,Uemoto Shinji,Sakai Yoshiharu,Taketo Makoto Mark
- Gastroenterology 145(5), 1064-1075.e11, 2013-11
- … [Background & Aims]Loss of the tumor suppressor SMAD4 correlates with progression of colorectal cancer (CRC). … SMAD4 bound directly to the promoter region of the CCL15 gene to negatively regulate its expression; … transforming growth factor-β increased binding of SMAD4 to the CCL15 promoter and transcriptional repression. …
- NAID 120005348333
- Increased transcription of RPL40A and RPL40B is important for the improvement of RNA production in Saccharomyces cerevisiae(GENETICS, MOLECULAR BIOLOGY, AND GENE ENGINEERING)
- Khatun Fahmida,Kurata Kenta,Chuwattanakul Varesa,Sugiyama Minetaka,Kaneko Yoshinobu,Harashima Satoshi
- Journal of bioscience and bioengineering 116(4), 423-432, 2013-10
- … The gene RRN10, which encodes, a component of the upstream activation factor, is essential to promote high-level transcription of rDNA. … In our previous study, we isolated SupE strain as a dominant suppressor, which showed the ability to restore the severe growth defects and reduced RNA content caused by disruption of the RRN10 gene. …
- NAID 110009675454
- Effects on vesicular transport pathways at the late endosome in cells with limited very long-chain fatty acids
- Obara Keisuke,Kojima Ryo,Kihara Akio
- Journal of Lipid Research 54(3), 831-842, 2013-03
- … In the presented study, we screened for multicopy suppressors that rescued temperature-sensitive growth of VLCFA-limited yeast cells, and identified the VPS21 gene, encoding a Rab GTPase, as such a suppressor. … When the vps21Δ mutation was introduced into a deletion mutant of the SUR4 gene, which encodes a VLCFA elongase, a synthetic growth defect was observed. …
- NAID 120005228358
Related Links
- tumor suppressor gene n. A gene that suppresses cellular proliferation. When inherited in a mutated state, it is associated with the development of various cancers, including most familial cancers. Also called antioncogene. tumor ...
- We previously reported the identification of TUSC1 (Tumor Suppressor Candidate 1), as a novel intronless gene isolated from a region of homozygous deletion at D9S126 on chromosome 9p in human lung cancer. In this ...
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★リンクテーブル★
| リンク元 | 「antioncogene」「cancer suppressor gene」「metastasis suppressor gene」「成長抑制遺伝子」 |
| 関連記事 | 「suppress」「grow」「suppressor」「growth」 |
「antioncogene」
- 関
- anti-oncogene、cancer suppressor gene、growth suppressor gene、metastasis suppressor gene、recessive oncogene、tumor suppressor gene
「cancer suppressor gene」
- 関
- anti-oncogene、antioncogene、growth suppressor gene、metastasis suppressor gene、recessive oncogene、tumor suppressor gene
「metastasis suppressor gene」
- 関
- anti-oncogene、antioncogene、cancer suppressor gene、growth suppressor gene、recessive oncogene、tumor suppressor gene
「成長抑制遺伝子」
「suppress」
- v.
- 抑制する、抑える、抑止する
- 関
- abrogate、abrogation、arrest、curb、depress、depression、inhibit、inhibition、restrain、restraint、subdue、suppression
「grow」
- v.
「suppressor」
「growth」
- n.
- 成長