ゲスターゲン試験
WordNet
- undergo a test; "She doesnt test well"
- any standardized procedure for measuring sensitivity or memory or intelligence or aptitude or personality etc; "the test was standardized on a large sample of students" (同)mental test, mental testing, psychometric test
- the act of undergoing testing; "he survived the great test of battle"; "candidates must compete in a trial of skill" (同)trial
- the act of testing something; "in the experimental trials the amount of carbon was measured separately"; "he called each flip of the coin a new trial" (同)trial, run
- a hard outer covering as of some amoebas and sea urchins
- put to the test, as for its quality, or give experimental use to; "This approach has been tried with good results"; "Test this recipe" (同)prove, try, try out, examine, essay
- achieve a certain score or rating on a test; "She tested high on the LSAT and was admitted to all the good law schools"
- determine the presence or properties of (a substance)
- show a certain characteristic when tested; "He tested positive for HIV"
- an examination of the characteristics of something; "there are laboratories for commercial testing"; "it involved testing thousands of children for smallpox"
- the act of subjecting to experimental test in order to determine how well something works; "they agreed to end the testing of atomic weapons"
- tested and proved useful or correct; "a tested method" (同)tried, well-tried
- tested and proved to be reliable (同)time-tested, tried, tried and true
PrepTutorEJDIC
- (人の能力などの)『試験』,考査,テスト / (物事の)『試験』,検済,試錬,実験《+of+名》 / 化学分析;試薬 / =test match / …‘を'『試験する』,検査する / …‘を'化学分析する / (…の)試験を受ける,試験をする《+for+名》
- testis の複数形
UpToDate Contents
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English Journal
- HPLC-MS/MS analysis of steroid hormones in environmental water samples.
- Avar P1, Maasz G1,2, Takács P3, Lovas S2, Zrinyi Z2, Svigruha R4, Takátsy A1, Tóth LG3, Pirger Z2.
- Drug testing and analysis.Drug Test Anal.2015 Jun 7. doi: 10.1002/dta.1829. [Epub ahead of print]
- Today, freshwaters, such as lakes and rivers, are subject to controlled pollution. Steroid hormones are chemically very stable highly lipophilic molecules. Their biological properties have a strong impact on the endocrine regulation of species. Steroids have estrogenic, androgenic, thyroidogenic or
- PMID 26059287
- 17β-Estradiol and natural progesterone for menopausal hormone therapy: REPLENISH phase 3 study design of a combination capsule and evidence review.
- Mirkin S1, Amadio JM2, Bernick BA2, Pickar JH3, Archer DF4.
- Maturitas.Maturitas.2015 May;81(1):28-35. doi: 10.1016/j.maturitas.2015.02.266. Epub 2015 Mar 9.
- Several formulations combining estrogens and progestins for hormone therapy (HT) have been approved worldwide for the treatment of menopausal symptoms, yet recent data indicate a decline in their use and an increase in compounded bioidentical HT. Up to now, no single product combining natural 17β-e
- PMID 25835751
- Maternal use of fertility drugs and risk of cancer in children--a nationwide population-based cohort study in Denmark.
- Hargreave M1, Jensen A, Nielsen TS, Colov EP, Andersen KK, Pinborg A, Kjaer SK.
- International journal of cancer. Journal international du cancer.Int J Cancer.2015 Apr 15;136(8):1931-9. doi: 10.1002/ijc.29235. Epub 2014 Oct 6.
- Large population-based studies are needed to examine the effect of maternal use of fertility drugs on the risk of cancer in children, while taking into account the effect of the underlying infertility. A cohort of 123,322 children born in Denmark between 1964 and 2006 to 68,255 women who had been ev
- PMID 25257918
Japanese Journal
- 牛血液用プロジェステロン測定キットを応用した犬の血漿中ジェスタージェン濃度測定による交配適期診断の実用性
- Early Pregnancy Diagnosis in the Sow by Fecal Gestagen Measurement Using a Bovine Milk Progesterone Qualitative Test EIA Kit
- MORIYOSHI Masaharu,NOZOKI Kouya,OHTAKI Tadatoshi,NAKADA Ken,NAKAO Toshihiko
- The Journal of reproduction and development 43(4), 345-350, 1997-11-01
- … An attempt was made to measure the qualitative fecal gestagen concentration in the sow using a commercial bovine milk progesterone qualitative test EIA kit (qualitative kit), which can measure the gestagen concentration in approximately 10 min. Additionally, the possibility of applying this method of gestagen concentration measurement to early pregnancy diagnosis in the sow was investigated. …
- NAID 10027567839
Related Links
- 無月経患者をみるとき, まず gestagen test より開始するものと考えられる.しかし, その適正な投与量についてはつきり線をひくことがむつかしい程, いろいろな gestagen test が行われている.今回, 著者らはこの点につき内分泌環境, BBTの検討 ...
- ※Gestagen､Estrogen Test を行って､消退性出血の出現を 確認し､ ※子宮性無月経を除外した後､ 経口投与を開始する｡ 通常､ 第1クール 1日クエン酸クロミフェン として50mg 5日間で開始し､ 第1クールで無効な場合は 1日100mg 5日間に ...
★リンクテーブル★
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- 英
- clomiphene, clomifene
- 化
- クエン酸クロミフェン クロミフェンクエン酸塩 clomifene citrate clomifeni citras
- 同
- クロラミフェン chloramiphene
- 商
- クロミッド、セロフェン、スパクロミン
- 関
- エンクロミフェン、エストロゲン。クロミフェン療法
作用機序
- 弱いエストロゲン作用と中程度の抗エストロゲン作用を有しており、視床下部のエストロゲン受容体に競合的に結合して(ネガティブフィードバックを解除することで？。単なる競合阻害薬として作用するのであろう)、ゴナドトロピン放出ホルモン、ゴナドトロピンの分泌を促す。
- ⇔ GnRHアゴニスト(GnRH受容体アゴニスト。下垂体のGnRH受容体のダウンレギュレーションを狙って用いられる。これによりゴナドトロピンの分泌が抑制される。)
薬理作用
適応
排卵誘発
- 投与方法：月経第5日から5日間
- 排卵率：70-80%
- 1-5の卵胞が成熟卵胞となる ⇔ hMG刺激では数個から十数個の卵胞が成熟卵胞となる。
禁忌
重要な基本的注意
- 参考1
- (1) 投与前少なくとも1ヵ月間及び治療期間中は基礎体温を必ず記録させ，排卵誘発の有無を観察すること。
- (2) 無月経患者においては投与前にgestagen testを行い，消退性出血開始日を第1日として5日目に，また投与前に自然出血（無排卵周期症）があった場合はその5日目に投与を開始すること。
- (3) 投与後基礎体温が高温相に移行した場合は，投与を中止し，必ず妊娠成立の有無を確認すること。
副作用
- 頚管粘液低下、子宮内膜発育不良(抗エストロゲン作用に基づく)
- 参考1
- 卵巣過剰刺激(≧5%。下腹部痛等の卵巣腫大症状)、虚血性視神経症(≧5%)、霧視等の視覚症状(＞0.1-5%未満)、過敏症(≧5%。発疹等)、精神変調(≧5%)、頭痛・情動不安等(0.1-5％未満)、肝臓酵素異常(≧5%。AST上昇,ALT上昇,ビリルビン上昇,γ-GTP上昇)、肝機能低下(＜0.1%。5%以上のBSP排泄遅延)、悪心・嘔吐・食欲不振等(＜0.1-5%)、顔面潮紅・尿量増加・口渇・疲労感(＜0.1-5%)
臨床関連
参考
- http://www.info.pmda.go.jp/go/pack/2499009F1080_1_03/2499009F1080_1_03
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- 英
- gestagen test
[show details]
[★]
- 英
- gestagen test
- 関
- プロゲスチン、ゲスターゲン
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- 関
- assessment、data quality、exam、examination、examine、experimental design、matched group、measurement、research design、scoring method、test、trial
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テスト