expanded disability status scale

• 総合障害度評価尺度

関

EDSS

WordNet

1. take by attacking with scaling ladders; "The troops scaled the walls of the fort"
2. a specialized leaf or bract that protects a bud or catkin (同)scale leaf
3. an ordered reference standard; "judging on a scale of 1 to 10" (同)scale of measurement, graduated table, ordered series
4. relative magnitude; "they entertained on a grand scale"
5. size or measure according to a scale; "This model must be scaled down"
6. the ratio between the size of something and a representation of it; "the scale of the map"; "the scale of the model"
7. a measuring instrument for weighing; shows amount of mass (同)weighing machine
8. a flattened rigid plate forming part of the body covering of many animals
9. an indicator having a graduated sequence of marks
10. (music) a series of notes differing in pitch according to a specific scheme (usually within an octave) (同)musical scale
11. a thin flake of dead epidermis shed from the surface of the skin (同)scurf, exfoliation
12. remove the scales from; "scale fish" (同)descale
13. reach the highest point of; "We scaled the Mont Blanc" (同)surmount
14. climb up by means of a ladder
15. measure by or as if by a scale; "This bike scales only 25 pounds"
16. measure with or as if with scales; "scale the gold"
17. pattern, make, regulate, set, measure, or estimate according to some rate or standard
18. make bigger or wider in size, volume, or quantity; "expand the house by adding another wing"
19. become larger in size or volume or quantity; "his business expanded rapidly"
20. extend in one or more directions; "The dough expands" (同)spread out
21. the condition of being unable to perform as a consequence of physical or mental unfitness; "reading disability"; "hearing impairment" (同)disablement, handicap, impairment
22. the relative position or standing of things or especially persons in a society; "he had the status of a minor"; "the novel attained the status of a classic"; "atheists do not enjoy a favorable position in American life" (同)position
23. the act of arranging in a graduated series (同)grading
24. act of measuring or arranging or adjusting according to a scale
25. ascent by or as if by a ladder

PrepTutorEJDIC

1. 《しばしば複数形で》『てんびん』,はかり / てんびんのさら / 《重量を表す副詞[句]を伴って》…の目方(体重)がある / …‘を'てんびんではかる
2. (蛇・魚類などの)うろこ / うろこ状の物;(ペンキ・さび・ふけなどの)爆片 / 〈魚など〉‘の'うろこを取る;…‘の'皮をはぐ / (…から)〈ペンキなどの薄泰〉‘を'そぎ取る《+『名』+『off』(『from』)+『名』》 / (…から)〈ペンキなどが〉かげ落ちる《+『off』(『from』)+『名』》
3. 『段階』,等級,階級 / 『比率』,縮尺 / (物差しなどの)『目盛り』 / (目盛りの付いた)『物差し』;温度計,(各種の)スケール / 『規模』,スケール / 音階 / 記数法,…進法 / …‘を'よじ登る / (…に合わせて)…‘を'調整する《+『名』+『to』+『名』》 / …‘を'縮尺で製図(設計)する
4. (…にまで)『拡大する』,膨張する,広がる《+『into』+『名』》 / (…について)さらに詳しく述べる《+『on』(『upon』)+『名』》 / 〈人が〉打ち解ける,心を開く / …‘を'『拡大する』,拡張する,広げる;…‘を'拡大して(…に)する《+『名』+『into』+『名』》
5. 〈U〉無力,無能 / 〈C〉不具,欠陥 / 〈U〉(法律で)無能力,無資格
6. 〈C〉〈U〉『地位』,身分;資格 / 〈U〉高い地位, / 〈C〉『状態』,事態

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/04/15 15:02:06」(JST)

wiki en

[Wiki en表示]

The Kurtzke Expanded Disability Status Scale (EDSS) is a method of quantifying disability in multiple sclerosis. The scale has been developed by John F. Kurtzke.

The EDSS quantifies disability in eight Functional Systems (FS) and allows neurologists to assign a Functional System Score (FSS) in each of these.

First public EDSS calculator (http://edss.neurol.ru) is developed, which allows to standardisation of neurostatus scoring.

Functional systems

Kurtzke defines functional systems as follows:

• pyramidal
• cerebellar
• brainstem
• sensory
• bowel and bladder
• visual
• cerebral
• other

Results and clinical meaning

EDSS steps 1.0 to 4.5 refer to people with MS who are fully ambulatory. EDSS steps 5.0 to 9.5 are defined by the impairment to ambulation.

The clinical meaning of each possible result is the following:

• 0.0: Normal Neurological Exam
• 1.0: No disability, minimal signs on 1 FS
• 1.5: No disability, minimal signs on 2 of 7 FS
• 2.0: Minimal disability in 1 of 7 FS
• 2.5: Minimal disability in 2 FS
• 3.0: Moderate disability in 1 FS; or mild disability in 3 - 4 FS, though fully ambulatory
• 3.5: Fully ambulatory but with moderate disability in 1 FS and mild disability in 1 or 2 FS; or moderate disability in 2 FS; or mild disability in 5 FS
• 4.0: Fully ambulatory without aid, up and about 12hrs a day despite relatively severe disability. Able to walk without aid 500 meters
• 4.5: Fully ambulatory without aid, up and about much of day, able to work a full day, may otherwise have some limitations of full activity or require minimal assistance. Relatively severe disability. Able to walk without aid 300 meters
• 5.0: Ambulatory without aid for about 200 meters. Disability impairs full daily activities
• 5.5: Ambulatory for 100 meters, disability precludes full daily activities
• 6.0: Intermittent or unilateral constant assistance (cane, crutch or brace) required to walk 100 meters with or without resting
• 6.5: Constant bilateral support (cane, crutch or braces) required to walk 20 meters without resting
• 7.0: Unable to walk beyond 5 meters even with aid, essentially restricted to wheelchair, wheels self, transfers alone; active in wheelchair about 12 hours a day
• 7.5: Unable to take more than a few steps, restricted to wheelchair, may need aid to transfer; wheels self, but may require motorized chair for full day's activities
• 8.0: Essentially restricted to bed, chair, or wheelchair, but may be out of bed much of day; retains self care functions, generally effective use of arms
• 8.5: Essentially restricted to bed much of day, some effective use of arms, retains some self care functions
• 9.0: Helpless bed patient, can communicate and eat
• 9.5: Unable to communicate effectively or eat/swallow
• 10.0: Death due to MS

References

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

• 1. Clinical features of multiple sclerosis in adults
• 2. Clinical course and classification of multiple sclerosis
• 3. 成人における再発寛解型多発性硬化症の治療 treatment of relapsing remitting multiple sclerosis in adults
• 4. 成人における多発性硬化症の診断 diagnosis of multiple sclerosis in adults
• 5. 成人における進行性多発性硬化症の治療 treatment of progressive multiple sclerosis in adults

English Journal

• Iron deposition in the precentral grey matter in patients with multiple sclerosis: A quantitative study using susceptibility-weighted imaging.

• Rumzan R, Wang JJ, Zeng C, Chen X, Li Y, Luo T, Lv F, Wang ZP, Hou H, Huang F.SourceDepartment of Radiology, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuzhong District, Chongqing 400016, China. Electronic address: minouchka_16@yahoo.com.
• European journal of radiology.Eur J Radiol.2013 Feb;82(2):e95-9. doi: 10.1016/j.ejrad.2012.09.006. Epub 2012 Oct 16.
• PURPOSE: Several studies suggest that iron deposition may play a role in multiple sclerosis (MS) pathology. Three-dimensional (3D) enhanced T2*-weighted angiography (ESWAN) at 3T was used to quantify iron deposition in the precentral grey matter in MS and its relationship with disease duration, atro
• PMID 23079047

• Assessment of prevalence and pathological response to orthostatic provocation in patients with multiple sclerosis.

• Adamec I, Bach I, Barušić AK, Mišmaš A, Habek M.SourceUniversity Hospital Center Zagreb, Department of Neurology, Referral Center for Demyelinating Diseases of the Central Nervous System, Zagreb, Croatia.
• Journal of the neurological sciences.J Neurol Sci.2013 Jan 15;324(1-2):80-3. doi: 10.1016/j.jns.2012.10.006. Epub 2012 Nov 3.
• OBJECTIVE: The aim of this study was to determine the prevalence of pathologic response to orthostatic challenge in patients with relapsing remitting multiple sclerosis (RRMS) and the difference of the response in patients in relapse and remission.PATIENTS AND METHODS: We included 112 RRMS patients;
• PMID 23127354

Japanese Journal

• スポンサードシンポジウム3  視神経脊髄炎に対するTocilizumab療法

• 荒木 学,松岡 貴子,中村 雅一,三宅 幸子,岡本 智子,村田 美穂,荒浪 利昌,山村 隆
• 日本臨床免疫学会会誌 36(5), 306-306, 2013
• …  女性4名，男性1名に，月1回TCZ 8 mg/kgを12ヶ月間投与し，年間再発回数（Annualized relapse rate : ARR），総合障害度評価尺度（Expanded disability status scale : EDSS），痛みと疲労の評価尺度（Numerical rating scale : NRS）が有意に改善した．また，多くの症例で抗AQP4抗体価が低下した．TCZ治療により再発回数の減少のみならず，治療抵抗性の慢性疼痛に効果 …
• NAID 130003382988

• Efficacy of Intravenous Cyclophosphamide Therapy for Neuromyelitis Optica Spectrum Disorder

• Yaguchi Hiroaki,Sakushima Ken,Takahashi Ikuko,Nishimura Hiroaki,Yashima-Yamada Moemi,Nakamura Masakazu,Tsuzaka Kazufumi,Maruo Yasunori,Takahashi Toshiyuki,Yabe Ichiro,Sasaki Hidenao
• Internal Medicine 52(9), 969-972, 2013
• … The expanded disability status scale (EDSS) score was used to evaluate the degree of severity. …
• NAID 130003366010

• 多発性硬化症入院患者に対する理学療法の有用性について

• 橋田 剛一,井上 悟,阿部 和夫
• 甲南女子大学研究紀要. 看護学・リハビリテーション学編 = Studies in nursing and rehabilitation (2), 107-112, 2009-03-19
• … 方法は、リハビリ部の入院病歴録から、①PT平均施行回数、②PTアプローチ内容、③PT開始時と終了時の Expanded Disability Status Scale (EDSS)による重症度の評価、④PT開始時と終了時のBarthel Index（以下BI）による重症度の評価を行った。 …
• NAID 120005182177

Related Links

• 神経症状評価尺度（EDSS）とは - MSゲートウェイ

このページでは神経症状評価尺度について説明します。MS(多発性硬化症)で使用され る総合障害度のスケールEDSS （Expanded Disability Status Scale）は、Kurtzke尺度 としても知られています。インターフェロンベータなどのMS治療法の臨床試験で使用 ...

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★リンクテーブル★

リンク元	「EDSS」「総合障害度評価尺度」
関連記事	「scale」「expand」「disability」「scaling」「status」

「EDSS」

　　[★]

• 総合障害度評価尺度

関

expanded disability status scale

「総合障害度評価尺度」

　　[★]

英

expanded disability status scale、EDSS

「scale」

　　[★]

• n.

• 1. (魚・は虫類の)うろこ。(チョウ・ガの)鱗粉。(皮膚の)鱗屑。薄片。(植物)芽鱗、鱗片。(動物)カイガラムシ。(金属を熱したときにできる)薄い酸化膜、スケール。(ボイラーややかんの内側にできる)湯垢。歯石。
• 2. 目盛り、定規、物差し、尺度、基準。(地図などの)縮尺比、縮尺目盛り。階級、等級。規模、スケール
• 3. はかり、てんびん

• vt.
• vi.

　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　

「expand」

　　[★]

• v.

• 拡大する、膨張する、広がる、発展する、(ペプチド鎖などが)伸長する

関

develop、development、dilatation、dilate、dilation、distend、distention、elongate、elongation、enlarge、enlargement、evolution、expansion、extend、extension、inflate、inflation、magnify、outgrowth、spread、stretch、swell、swelling

　 　 　 　

「disability」

　　[★]

• n.

• 無能、無力。(法律上の)行為無能力、無資格
• (身体などの)不利な条件、障害、ハンディキャップ

• adj.

• (身体の)障害の。

　 　

「scaling」

　　[★]

• n.

• スケーリング

• 縮尺や変換係数を定めること、歯石とプラークを除去すること

　 　 　

「status」

　　[★]

• n.

• 状態

関

condition、position、situation、state