薬剤性奇形
WordNet
- reason or establish by induction
- cause to arise; "induce a crisis" (同)bring_on
- produce electric current by electrostatic or magnetic processes (同)induct
- cause to do; cause to act in a specified manner; "The ads induced me to buy a VCR"; "My children finally got me to buy a computer"; "My wife made me buy a new sofa" (同)stimulate, cause, have, get, make
- cause to occur rapidly; "the infection precipitated a high fever and allergic reactions" (同)stimulate, rush, hasten
- use recreational drugs (同)do drugs
- administer a drug to; "They drugged the kidnapped tourist" (同)dose
- a substance that is used as a medicine or narcotic
- something abnormal or anomalous (同)miscreation
- brought about or caused; not spontaneous; "a case of steroid-induced weakness"
PrepTutorEJDIC
- 〈人〉‘に'『勧めて』(…)『させる』 / …‘を'『引き起こす』,もたらす(cause) / 〈電気〉‘を'誘導する / …‘を'帰納する
- 『薬』,薬品,薬剤 / 『麻薬』,麻酔剤 / 〈人〉‘に'薬(特に麻酔剤)を与える / 〈飲食物〉‘に'(麻酔薬・毒薬などの)薬を混ぜる
- (特に生物体の)奇形;{C}奇形部分
UpToDate Contents
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English Journal
- Maternal rat serum concentrations of dimethadione do not explain intra-litter differences in the incidence of dimethadione-induced birth defects, including novel findings in foetal lung.
- Rodger I1, Lam I2, Purssell E3, Thompson M4, Rutter A5, Ozolinš TR6.
- Toxicology.Toxicology.2014 Dec 4;326:142-52. doi: 10.1016/j.tox.2014.10.014. Epub 2014 Nov 1.
- To investigate mechanisms of chemical-induced congenital heart defects (CHD) we have developed a rat model using dimethadione (DMO), the N-demethylated metabolite of the anticonvulsant, trimethadione (TMD). Dosing pregnant rats with 300mg/kg DMO every 12h from the evening of gestational day (GD) 8 u
- PMID 25446330
- Esophageal atresia and prenatal exposure to mycophenolate.
- Martín MC1, Cristiano E2, Villanueva M3, Bonora ML4, Berguio N5, Tocci A6, Groisman B7, Bidondo MP8, Liascovich R9, Barbero P10.
- Reproductive toxicology (Elmsford, N.Y.).Reprod Toxicol.2014 Dec;50:117-21. doi: 10.1016/j.reprotox.2014.10.015. Epub 2014 Oct 25.
- Mycophenolate mofetil is a widely prescribed immunosuppressive agent for transplant patients and autoimmune diseases. Potential teratogenic effects after in utero exposure to mycophenolate mofetil has been described in human clinical observations. The complete clinical pattern is still being delinea
- PMID 25461910
- A human ether-á-go-go-related (hERG) ion channel atomistic model generated by long supercomputer molecular dynamics simulations and its use in predicting drug cardiotoxicity.
- Anwar-Mohamed A1, Barakat KH2, Bhat R3, Noskov SY4, Tyrrell DL5, Tuszynski JA6, Houghton M7.
- Toxicology letters.Toxicol Lett.2014 Nov 4;230(3):382-92. doi: 10.1016/j.toxlet.2014.08.007. Epub 2014 Aug 13.
- Acquired cardiac long QT syndrome (LQTS) is a frequent drug-induced toxic event that is often caused through blocking of the human ether-á-go-go-related (hERG) K(+) ion channel. This has led to the removal of several major drugs post-approval and is a frequent cause of termination of clinical trial
- PMID 25127758
Japanese Journal
- Utility of CT enteroclysis for small intestinal hemorrhage
- The bulletin of the Yamaguchi Medical School 58(1-2), 11-18, 2011
- … Results : CTE findings were obtained for 17 of 41 patients (41%), suggesting vascular malformation in 9 patients (22%), inflammatory bowel disease in 7 (17%), and small intestinal tumor in 1 (2%). …
- NAID 80022211751
- Children's toxicology from bench to bed - Drug-induced Renal Injury (1) : The toxic effects of ARB/ACEI on fetal kidney development
- Sekine Takashi,Miura Ken-ichiro,Takahashi Kazuhiro [他],Igarashi Takashi
- Journal of toxicological sciences 34(Special Issue II), SP245-SP250, 2009-07
- … In humans, maternal administration of agents with inhibitory effects on the RAS system, such as angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin type 1 receptor blockers (ARBs), have been reported to cause severe renal malformation, designated as ACEI/ARB fetopathy. …
- NAID 110007337714
- Subarachnoid and Intracerebral Hemorrhage Associated with Necrotizing Angiitis Due to Methamphetamine Abuse : An Autopsy Case
- SHIBATA Shobu,MORI Kazuo,SEKINE Ichiro,SUYAMA Hirofumi
- Neurologia medico-chirurgica 31(1), 49-52, 1991-01-15
- … Postmortem studies found cerebral edema, subarachnoid, intraventricular, and intracerebral hemorrhage, and intracranial vasculitis, but no aneurysm or arteriovenous malformation. … The hemorrhage probably resulted from medial necrosis in the large intracerebral vessels, and a sudden drug-induced rise in blood pressure. …
- NAID 110002278167
Related Links
- 1. Yonsei Med J. 2009 Jun 30;50(3):445-7. doi: 10.3349/ymj.2009.50.3.445. Epub 2009 Jun 23. A case of suspected isotretinoin-induced malformation in a baby of a mother who became pregnant one month after discontinuation of the ...
- ... which result from environmental or iatrogenic exposures during pregnancy. The final manifestations of drug-induced abnormal development can be death, malformation, growth retardation, or functional disorder. In considering the ...
★リンクテーブル★
[★]
- 英
- drug-induced malformation, malformation due to teratogenic agents
[★]
- 誘発する、誘導する、誘起する、導入する、引き起こす
- 関
- cause、challenge、derivation、elicit、elicitation、evocation、evoke、guidance、induction、inductive、introduce、introduction、precipitate、provocation、provoke、spark
[★]
-malformation
L. 138
- 関
- abnormality、deformity、dysgenesis、dysplasia、dysplastic、malformed、teratologic
[★]
-
- hypercalcaemia induced pancreatitis 高カルシウム血症による膵炎
[★]
- 同
- drugs