cyclic GMP-dependent protein kinase

• サイクリックGMP依存性プロテインキナーゼ

関

cGMP-dependent protein kinase、protein kinase G

WordNet

1. relying on or requiring a person or thing for support, supply, or what is needed; "dependent children"; "dependent on moisture"
2. addicted to a drug (同)dependant, drug-addicted, hooked, strung-out
3. contingent on something else (同)dependant, qualified
4. (of a clause) unable to stand alone syntactically as a complete sentence; "a subordinate (or dependent) clause functions as a noun or adjective or adverb within a sentence" (同)subordinate
5. of a compound having atoms arranged in a ring structure
6. recurring in cycles (同)cyclical
7. conforming to the Carnot cycle
8. forming a whorl or having parts arranged in a whorl; "cyclic petals"; "cyclic flowers"
9. marked by repeated cycles
10. any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
11. an enzyme that catalyzes the conversion of a proenzyme to an active enzyme

PrepTutorEJDIC

1. 『頼っている』,依存している,従属している / 扶養される人(家族)
2. 蛋白(たんばく)質

UpToDate Contents

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• 1. 血小板生物学 platelet biology
• 2. 止血の概要 overview of hemostasis
• 3. 血管内皮機能および血栓溶解療法の基本的メカニズム vascular endothelial function and fundamental mechanisms of fibrinolysis thrombolysis
• 4. 切迫早産の予防 inhibition of acute preterm labor
• 5. 冠動脈内皮細胞機能不全：基本概念 coronary artery endothelial dysfunction basic concepts

English Journal

• Cyclic GMP-mediated memory enhancement in the object recognition test by inhibitors of phosphodiesterase-2 in mice.

• Lueptow LM1,2, Zhan CG3, O'Donnell JM4.
• Psychopharmacology.Psychopharmacology (Berl).2016 Feb;233(3):447-56. doi: 10.1007/s00213-015-4129-1. Epub 2015 Nov 2.
• RATIONALE AND OBJECTIVES: Cyclic nucleotide phosphodiesterase-2 (PDE2) is a potential therapeutic target for the treatment of cognitive dysfunction. Using the object recognition test (ORT), this study assessed the effects of two PDE2 inhibitors, Bay 60-7550 and ND7001, on learning and memory, and ex
• PMID 26525565

• Lipopolysaccharide-induced serotonin transporter up-regulation involves PKG-I and p38MAPK activation partially through A3 adenosine receptor.

• Zhao R1, Wang S, Huang Z, Zhang L, Yang X, Bai X, Zhou D, Qin Z, Du G.
• Bioscience trends.Biosci Trends.2016;9(6):367-76. doi: 10.5582/bst.2015.01168.
• Serotonin transporter (SERT) is a critical determinant of synaptic serotonin (5-hydroxytryptamine, 5-HT) inactivation which plays a critical role in the pathology of depression and other mood disorders. Lipopolysaccharide (LPS), a potent activator of the inflammatory system, has been reported to cau
• PMID 26781794

• Phosphodiesterase 1 regulation is a key mechanism in vascular aging.

• Niño PK1, Durik M2, Danser AH3, de Vries R3, Musterd-Bhaggoe UM3, Meima ME4, Kavousi M5, Ghanbari M5, Hoeijmakers JH6, O'Donnell CJ7, Franceschini N8, Janssen GM9, De Mey JG10, Liu Y11, Shanahan CM11, Franco OH5, Dehghan A5, Roks AJ12.
• Clinical science (London, England : 1979).Clin Sci (Lond).2015 Dec;129(12):1061-75. doi: 10.1042/CS20140753. Epub 2015 Jun 25.
• Reduced nitric oxide (NO)/cGMP signalling is observed in age-related vascular disease. We hypothesize that this disturbed signalling involves effects of genomic instability, a primary causal factor in aging, on vascular smooth muscle cells (VSMCs) and that the underlying mechanism plays a role in hu
• PMID 26464516

Japanese Journal

• Lipopolysaccharide-induced serotonin transporter up-regulation involves PKG-I and p38MAPK activation partially through A3 adenosine receptor

• BioScience Trends 9(6), 367-376, 2015
• NAID 130005120097

• Cyclic GMP-Dependent Signaling in Cardiac Myocytes

• Circulation journal : official journal of the Japanese Circulation Society 76(8), 1819-1825, 2012-07-25
• NAID 10030504080

• Nitric Oxide and Carbon Monoxide Act as Inhibitory Neurotransmitters in the Longitudinal Muscle of C57BL/6J Mouse Distal Colon

• Journal of pharmacological sciences 112(2), 231-241, 2010-02-20
• NAID 10029889058

Related Links

• cGMP-dependent protein kinase - Wikipedia, the free encyclopedia

cGMP-dependent protein kinase or Protein Kinase G (PKG) is a serine/threonine- specific protein kinase that is activated by cGMP. It phosphorylates a number of biologically important targets and is implicated in the regulation of smooth ...

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★リンクテーブル★

リンク元	「cGMP-dependent protein kinase」「サイクリックGMP依存性プロテインキナーゼ」
関連記事	「GMP」「cyclic」「dependent」「kinase」「G」

「cGMP-dependent protein kinase」

　　[★]

• サイクリックGMP依存性タンパク質リン酸化酵素、cGMP依存性タンパク質リン酸化酵素

関

cyclic GMP-dependent protein kinase、G-kinase、protein kinase G

「サイクリックGMP依存性プロテインキナーゼ」

　　[★]

英

cyclic GMP-dependent protein kinase

関

プロテインキナーゼG、cGMP依存性タンパク質リン酸化酵素

「GMP」

　　[★]

• グアノシン一リン酸、5'-guanylic acid、guanosine monophosphate、guanylic acid
• 医薬品及び医薬部外品の製造管理及び品質管理規則, 優良医薬品製造基準, 優良製造規範, Good Manufacturing Practice, good manufacturing practice

「cyclic」

　　[★]

• adj.

• 環状の、環式の、周期性の、サイクリック

関

annular、circular、cyclical、cyclicity、cyclo、periodic、periodicity

　 　 　 　 　

「dependent」

　　[★]

• adj.

• 依存性の、依存的な、依存型の、依存の

関

depend、dependence、dependency、dependently

　 　 　 　 　

「kinase」

　　[★] キナーゼ カイネース リン酸化酵素 phosphoenzyme phosphotransferase 　

「G」

　　[★]

• グアニン guanine
• グアノシン guanosine
• グリシン glycine