同: CAB

WordNet

having every necessary or normal part or component or step; "a complete meal"; "a complete wardrobe"; "a complete set of the Britannica"; "a complete set of china"; "a complete defeat"; "a complete accounting"
having come or been brought to a conclusion; "the harvesting was complete"; "the affair is over, ended, finished"; "the abruptly terminated interview" (同)concluded, ended, over, all_over, terminated
perfect and complete in every respect; having all necessary qualities; "a complete gentleman"; "consummate happiness"; "a consummate performance" (同)consummate
write all the required information onto a form; "fill out this questionnaire, please!"; "make out a form" (同)fill out, fill_in, make_out
come or bring to a finish or an end; "He finished the dishes"; "She completed the requirements for her Masters Degree"; "The fastest runner finished the race in just over 2 hours; others finished in over 4 hours" (同)finish
complete a pass (同)nail
bring to a whole, with all the necessary parts or elements; "A child would complete the family"
impose a blockade on (同)seal off
a war measure that isolates some area of importance to the enemy (同)encirclement
prevents access or progress
obstruct access to (同)block off
male sex hormone that is produced in the testes and responsible for typical male sexual characteristics (同)androgenic_hormone
caught; "a completed forward pass"
(of a marriage) completed by the first act of sexual intercourse after the ceremony
blocking entrance to and exit from seaports and harbors; "the blockading ships prevented delivery of munitions"

PrepTutorEJDIC

Civil Aeronautics Board民間航空委員会
(比較変化なし)『全部の』,完備した / 《名詞の前にのみ用いて》『完全な』,全くの / (比較変化なし)『完成した』,完結した / …'を'『仕上げる』,終える / …'を'完全なものにする,完成する
(軍事力による港・海岸線などの)封鎖,閉鎖 / 封鎖を行う軍隊 / 障害物,妨害物 / (軍事力により)〈港など〉'を'封鎖する
アンドロゲン(男性ホルモン)

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/04/05 20:31:12」(JST)

wiki en

Maximum androgen blockade (MAB) or complete or combined androgen blockade (CAB) is a medical treatment involving the combination of both androgen receptor (AR) antagonism and inhibition or suppression of androgen production to attain maximal effectiveness in androgen deprivation therapy.^[1] An example of MAB is the combination of bicalutamide, an AR antagonist, with a gonadotropin-releasing hormone (GnRH) GnRH analogue such as leuprorelin or cetrorelix.^[1] Cyproterone acetate and galeterone are examples of MAB that combine both mechanisms into a single drug. MAB was developed for and is employed in the treatment of prostate cancer.^[1]

References

^ ^a ^b ^c "Maximum androgen blockade in advanced prostate cancer: an overview of the randomised trials". The Lancet 355 (9214): 1491–1498. 2000. doi:10.1016/S0140-6736(00)02163-2. ISSN 0140-6736.

This pharmacology-related article is a stub. You can help Wikipedia by expanding it.

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 播種性前立腺癌に対する治療の概要 overview of the treatment of disseminated prostate cancer
2. Initial therapy for castration sensitive metastatic prostate cancer
3. 幼児および小児における一次救命処置 basic life support in infants and children
4. 限局性前立腺癌治療後の血清PSAの上昇：全身療法 rising serum psa after treatment for localized prostate cancer systemic therapy
5. 中等度～高リスク限局性前立腺癌の初期マネージメント initial management of regionally localized intermediate and high risk prostate cancer

English Journal

Hormone naïve prostate cancer: predicting and maximizing response intervals.

Moul JW1.
Asian journal of andrology.Asian J Androl.2015 Jun 26. doi: 10.4103/1008-682X.152821. [Epub ahead of print]
Hormone naïve advanced prostate cancer is subdivided into two disease states: biochemical recurrence and traditional M1 (metastatic) prostate cancer and characterized by no prior hormonal therapy or androgen deprivation therapy (ADT). In biochemical recurrence/prostate-specific antigen (PSA) recurr
PMID 26112479

Testosterone-induced relaxation involves L-type and store-operated Ca2+ channels blockade, and PGE 2 in guinea pig airway smooth muscle.

Perusquía M1, Flores-Soto E, Sommer B, Campuzano-González E, Martínez-Villa I, Martínez-Banderas AI, Montaño LM.
Pflügers Archiv : European journal of physiology.Pflugers Arch.2015 Apr;467(4):767-77. doi: 10.1007/s00424-014-1534-y. Epub 2014 May 29.
In vascular smooth muscle, it has been described that testosterone (TES) produces relaxation by blocking L-type Ca(2+) channels. Recently, we found that L-type Ca(2+) and store-operated Ca(2+) (SOC) channels are the main membranal structures that provide extracellular Ca(2+) for carbachol (CCh)-indu
PMID 24872164

Bicalutamide 150 mg as secondary hormonal therapy for castration-resistant prostate cancer.

Qian SB1, Shen HB, Cao QF, Zhang L, Chen YF, Qi J.
International urology and nephrology.Int Urol Nephrol.2015 Mar;47(3):479-84. doi: 10.1007/s11255-015-0919-y. Epub 2015 Feb 10.
PURPOSE: This study was aimed to evaluate the effect and tolerability of bicalutamide 150 mg therapy in patients with castration-resistant prostate cancer (CRPC).METHODS: A total of 48 patients with histologically confirmed prostate cancer were included. They had been treated with continuous maximal
PMID 25665794