- 関
- competitive antagonism、competitive blocking、competitive inhibition
WordNet
- a three-dimensional shape with six square or rectangular sides (同)cube
- (computer science) a sector or group of sectors that function as the smallest data unit permitted; "since blocks are often defined as a single sector, the terms `block and `sector are sometimes used interchangeably"
- support, secure, or raise with a block; "block a plate for printing"; "block the wheels of a car"
- a solid piece of something (usually having flat rectangular sides); "the pyramids were built with large stone blocks"
- housing in a large building that is divided into separate units; "there is a block of classrooms in the west wing"
- a rectangular area in a city surrounded by streets and usually containing several buildings; "he lives in the next block" (同)city block
- an inability to remember or think of something you normally can do; often caused by emotional tension; "I knew his name perfectly well but I had a temporary block" (同)mental_block
- a number or quantity of related things dealt with as a unit; "he reserved a large block of seats"; "he held a large block of the companys stock"
- interrupt the normal function of by means of anesthesia; "block a nerve"; "block a muscle"
- run on a block system; "block trains"
- shape by using a block; "Block a hat"; "block a garment"
- shape into a block or blocks; "block the graphs so one can see the results clearly"
- stamp or emboss a title or design on a book with a block; "block the book cover"
- showing a fighting disposition; "highly competitive sales representative"; "militant in fighting for better wages for workers"; "his self-assertive and ubiquitous energy" (同)militant
- involving competition or competitiveness; "competitive games"; "to improve ones competitive position" (同)competitory
- subscribing to capitalistic competition (同)free-enterprise, private-enterprise
- completely obstructed or closed off; "the storm was responsible for many blocked roads and bridges"; "the drain was plugged" (同)plugged
- closed to traffic; "the repaving results in many blocked streets" (同)out of use
- a group of countries in special alliance (同)axis
- the act of obstructing or deflecting someones movements (同)block
PrepTutorEJDIC
- (木・石などの,通例平らな面のある)『かたまり』 / 《米》(四団を街路に囲まれた)『区画』,街区 / 街区の1辺の距離(一般に40メートル前後) / 《英》ブロック(アパート・事務所・商店などに区切られている大きな建物) / 『妨害物』,障害物(obstacle);(障害によって生じた)停滞,渋滞 / 台木,台(まないた・肉切り台・まき割り台・せり売り台・帽子の木型など);《the~》炭頭台 / (特にアメリカンフットボールで)ブロック(相手の選手の突進を阻止する) / 滑車(pulley) / (座席券・株券などの)一組《+『of』+『名』》 / 〈通路など〉'を'『ふさぐ』,〈通行・進行など〉'を'妨げる / 〈帽子など〉の型取りをする / (特にアメリカンフットボールで)〈相手選手の突進〉'を'ブロックする;(ボクシングで)〈相手のパンチ〉'を'ブロックする
- 競争の,競争による
- ブロック,圏(地理・共通の利害・政治・経済上の目的などのために団結した団体・国家などの結合体)
UpToDate Contents
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English Journal
- Identification of Cyclin A Binders with a Fluorescent Peptide Sensor.
- Pazos E1, Mascareñas JL, Vázquez ME.
- Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2016;1336:67-83. doi: 10.1007/978-1-4939-2926-9_7.
- A peptide sensor that integrates the 4-dimethylaminophthalimide (4-DMAP) fluorophore in a short cyclin A binding sequence displays a large fluorescence emission increase upon interacting with the cyclin A Binding Groove (CBG). Competitive displacement assays of this probe allow the straightforward i
- PMID 26231709
- Protein-Protein Interaction for the De Novo Design of Cyclin-Dependent Kinase Peptide Inhibitors.
- Arumugasamy K1, Tripathi SK, Singh P, Singh SK.
- Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2016;1336:59-66. doi: 10.1007/978-1-4939-2926-9_6.
- The homology of the inhibitor binding site regions on the surface of cyclin-dependent kinases (CDKs) makes actual CDK inhibitors unable to bind specifically to their molecular targets. Most of them are ATP competitive inhibitors with low specificity that also affect the phosphorylation mechanisms of
- PMID 26231708
- Activation of Hsp90 Enzymatic Activity and Conformational Dynamics through Rationally Designed Allosteric Ligands.
- Sattin S1, Tao J2, Vettoretti G3, Moroni E3, Pennati M4, Lopergolo A4, Morelli L1, Bugatti A5, Zuehlke A6, Moses M6, Prince T6, Kijima T6, Beebe K6, Rusnati M5, Neckers L6, Zaffaroni N4, Agard DA2, Bernardi A1, Colombo G7.
- Chemistry (Weinheim an der Bergstrasse, Germany).Chemistry.2015 Sep 21;21(39):13598-608. doi: 10.1002/chem.201502211. Epub 2015 Aug 18.
- Hsp90 is a molecular chaperone of pivotal importance for multiple cell pathways. ATP-regulated internal dynamics are critical for its function and current pharmacological approaches block the chaperone with ATP-competitive inhibitors. Herein, a general approach to perturb Hsp90 through design of new
- PMID 26286886
Japanese Journal
- A Case of Cardiac Amyloidosis Whose Exercise Intolerance Was Caused by Loss of Bi-Ventricular Pacing after Atrial Contractions within Pacemaker Refractory Period
- Kuroyanagi Akira,Siraishi Hirokazu,Shirayama Takeshi,Matsubara Hiroaki
- Journal of Arrhythmia 27(Supplement), OP14_2, 2011
- … A 68-year-old man presented with congestive heart failure (NYHA III) with QRS morphology of left bundle branch block. … Intra-cardiac ECG during exercise showed a premature atrial contraction and/or a non-competitive atrial pacing (NCAP) within post-ventricular atrial refractory period (PVARP), followed by aborted ventricular pacing. …
- NAID 130002130489
- Cyclic Limulus Anti-lipopolysaccharide (LPS) Factor-Derived Peptide CLP-19 Antagonizes LPS Function by Blocking Binding to LPS Binding Protein
- Liu Yao,Ni Bing,Ren Jian-dong,Chen Jian-hong,Tian Zhi-qiang,Tang Min,Li Di,Xia Peiyuan
- Biological and Pharmaceutical Bulletin 34(11), 1678-1683, 2011
- … CLP-19 was found to block LPS binding to LBP in a dose-dependent manner, as evidenced by competitive enzyme-linked immunosorbent assay (ELISA). … Furthermore, CLP-19 potency in LPS antagonism in vitro and in vivo was directly associated with its ability to block the LPS-LBP interaction. …
- NAID 130001252849
- Competitive hydrogen bonds associated with the effect of primycin antibiotic on oleic acid as a building block of plasma membranes
- VIRAG Eszter,PESTI Miklos,KUNSAGI-MATE Sandor
- Journal of antibiotics 63(3), 113-117, 2010-03-25
- NAID 10030707873
Related Links
- 9 Feb 2001 ... Mouse myotubes were used to investigate effects of the nondepolarizing neuromuscular blocking drugs pancuronium and atracurium on embryonic-type nicotinic acety.
Related Pictures
★リンクテーブル★
[★]
- 英
- competitive antagonism、competitive block、competitive blocking
- 関
- 競合的拮抗、競合的阻害
[★]
- 英
- competitive inhibition、competitive block、competitive blocking
- 関
- 競合阻害、競合的遮断
[★]
- 関
- competitive block、competitive blocking
[★]
- 関
- competitive antagonism、competitive block、competitive inhibition
[★]
- 関
- blockade、blockage、deter、inhibit、inhibition、lump、prevent、prevention、repress、repression、seal、turn off
[★]
- 関
- compete、competition、competitively、competitiveness、contest、rival