WordNet

of or related to the synthetic phase of metabolism
characterized by or promoting constructive metabolism; "some athletes take anabolic steroids to increase muscle size temporarily"
the synthesis in living organisms of more complex substances (e.g., living tissue) from simpler ones together with the storage of energy (同)constructive metabolism
produce from basic elements or sources; change into a more developed product; "The bee elaborates honey"
work out in detail; "elaborate a plan" (同)work_out
add details, as to an account or idea; clarify the meaning of and discourse in a learned way, usually in writing; "She elaborated on the main ideas in her dissertation" (同)lucubrate, expatiate, exposit, enlarge, flesh out, expand, expound, dilate
marked by complexity and richness of detail; "an elaborate lace pattern" (同)luxuriant
developing in intricate and painstaking detail (同)working out

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(生物の)同化作用
『入念な』,手の込んだ / …‘を'念入りに仕上げる,練り上げる / (…について)詳細に述べる《+『on』(『upon, about』)+『名』(do『ing』)》
〈U〉(…を)念入りに作り上げる(仕上げる)こと《+『of』+『名』》 / 〈C〉念入りに作り上げたもの,労作

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/04/09 23:05:12」(JST)

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This article is about anabolism and catabolism as classifications of metabolism. For steroids with anabolic properties, see Anabolic steroid.

Anabolism (from Greek ana, "upward", and ballein, "to throw") is the set of metabolic pathways that construct molecules from smaller units.^[1] These reactions require energy. One way of categorizing metabolic processes, whether at the cellular, organ or organism level is as 'anabolic' or as 'catabolic', which is the opposite. Anabolism is powered by catabolism, where large molecules are broken down into smaller parts and then used up in respiration. Many anabolic processes are powered by adenosine triphosphate (ATP).^[2]

Anabolic processes tend toward "building up" organs and tissues. These processes produce growth and differentiation of cells and increase in body size, a process that involves synthesis of complex molecules. Examples of anabolic processes include the growth and mineralization of bone and increases in muscle mass. Endocrinologists have traditionally classified hormones as anabolic or catabolic, depending on which part of metabolism they stimulate. The classic anabolic hormones are the anabolic steroids, which stimulate protein synthesis and muscle growth, and insulin. The balance between anabolism and catabolism is also regulated by circadian rhythms, with processes such as glucose metabolism fluctuating to match an animal's normal periods of activity throughout the day.^[3]

References

^ de Bolster, M.W.G. (1997). "Glossary of Terms Used in Bioinorganic ChemKk isistry: Anabolism". International Union of Pure and Applied Chemistry. Archived from the original on 30 October 2007. Retrieved 2007-10-30.
^ Nicholls D.G. and Ferguson S.J. (2002) Bioenergetics Academic press 3rd edition ISBN 0-12-518121-3
^ Ramsey KM, Marcheva B, Kohsaka A, Bass J (2007). "The clockwork of metabolism". Annu. Rev. Nutr. 27: 219–40. doi:10.1146/annurev.nutr.27.061406.093546. PMID 17430084.

UpToDate Contents

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1. 運動能力の向上を目的としたアンドロゲンおよびその他のホルモンの使用 use of androgens and other hormones to enhance athletic performance
2. 性腺機能低下を呈する男性に対するテストステロン治療 testosterone treatment of male hypogonadism
3. HIV感染患者における組織の消耗の管理 management of tissue wasting in patients with hiv infection
4. Approach to the long-term survivor of colorectal cancer
5. 性腺機能低下を呈する男性の臨床的特徴および診断 clinical features and diagnosis of male hypogonadism

English Journal

Environmental disruption of circadian rhythm predisposes mice to osteoarthritis-like changes in knee joint.

Kc R1, Li X1, Voigt RM2, Ellman MB1,3, Summa KC4, Vitaterna MH4, Keshavarizian A2,5,6,7, Turek FW4, Meng QJ8, Stein GS9, van Wijnen AJ10, Chen D1, Forsyth CB2, Im HJ1,3,11,12,13.
Journal of cellular physiology.J Cell Physiol.2015 Sep;230(9):2174-83. doi: 10.1002/jcp.24946.
Circadian rhythm dysfunction is linked to many diseases, yet pathophysiological roles in articular cartilage homeostasis and degenerative joint disease including osteoarthritis (OA) remains to be investigated in vivo. Here, we tested whether environmental or genetic disruption of circadian homeostas
PMID 25655021

Expression, purification and preliminary crystallographic studies of human glutamate oxaloacetate transaminase 1 (GOT1).

Jiang X1, Chang H2, Zhou Y3.
Protein expression and purification.Protein Expr Purif.2015 Sep;113:102-6. doi: 10.1016/j.pep.2015.05.010. Epub 2015 May 21.
Glutamate oxaloacetate transaminase (GOT) catalyzes the reversible reaction of l-aspartate and α-ketoglutarate into oxaloacetate and l-glutamate and plays a key role in carbon and nitrogen metabolism in all organisms. In human tissues, GOTs are pyridoxal 5'-phosphate-dependent (PLP) enzymes which e
PMID 26003525

Ursolic acid derivatives as bone anabolic agents targeted to tryptophan hydroxylase 1 (Tph-1).

Fu HJ1, Zhao Y1, Zhou YR1, Bao BH1, Du Y1, Li JX2.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.Eur J Pharm Sci.2015 Aug 30;76:33-47. doi: 10.1016/j.ejps.2015.04.021. Epub 2015 Apr 28.
Tryptophan hydroxylase 1 (Tph-1) initiates the biosynthesis of peripheral serotonin. As peripheral serotonin suppresses bone formation, inhibitor of Tph-1 provides a useful tool to discover anabolic agents for osteoporosis. In the present study, series of ursolic acid (UA) derivatives were synthesiz
PMID 25930119

9-Demethoxy-medicarpin promotes peak bone mass achievement and has bone conserving effect in ovariectomized mice: Positively regulates osteoblast functions and suppresses osteoclastogenesis.

Goel A1, Raghuvanshi A2, Kumar A2, Gautam A3, Srivastava K3, Kureel J3, Singh D3.
Molecular and cellular endocrinology.Mol Cell Endocrinol.2015 Aug 15;411:155-66. doi: 10.1016/j.mce.2015.04.023. Epub 2015 May 5.
We report a new bone anabolic and anti-catabolic pterocarpan 9-demethoxy-medicarpin (DMM) for the management of postmenopausal osteoporosis. DMM promoted osteoblast functions via activation of P38MAPK/BMP-2 pathway and suppressed osteoclastogenesis in bone marrow cells (BMCs). In calvarial osteoblas
PMID 25957087

Japanese Journal

骨形成促進薬テリパラチドによる治療と課題 (特集骨粗鬆症 : 新たな骨粗鬆症治療薬と治療ストラテジー)

遠藤直人
最新医学 69(10), 1957-1961, 2014-10
NAID 40020231510

Chronic Reduction of GIP Secretion Alleviates Obesity and Insulin Resistance Under High-Fat Diet Conditions.

Nasteska Daniela,Harada Norio,Suzuki Kazuyo,Yamane Shunsuke,Hamasaki Akihiro,Joo Erina,Iwasaki Kanako,Shibue Kimitaka,Harada Takanari,Inagaki Nobuya
Diabetes 63(7), 2332-2343, 2014-07
… Gastric inhibitory polypeptide (GIP) exhibits potent insulinotropic effects on β-cells and anabolic effects on bone formation and fat accumulation. …
NAID 120005458283

A key role for neuropeptide Y in lifespan extension and cancer suppression via dietary restriction

Chiba Takuya,Tamashiro Yukari,Park Daeui,Kusudo Tatsuya,Fujie Ryoko,Komatsu Toshimitsu,Kim Sang Eun,Park Seongjoon,Hayashi Hiroko,Mori Ryoichi,Yamashita Hitoshi,Chung Hae Young,Shimokawa Isao
Scientific Reports 4, 4517, 2014-03-31
… In contrast, the physiological processes activated during adaptation to DR, including inhibition of anabolic signaling molecules (insulin and insulin-like growth factor-1), modulation of adipokine and corticosterone levels, and preferential fatty acid oxidation, were unaffected by the absence of Npy. …
NAID 120005438935

Application of a Heat Shock Protein Inducer to Remedy for an Atrophied Muscle Cell: A Basic Research for ISS/JEM Onboard Experiment

, , , , , ,
TRANSACTIONS OF THE JAPAN SOCIETY FOR AERONAUTICAL AND SPACE SCIENCES, AEROSPACE TECHNOLOGY JAPAN 12(ists29), Pp_7-Pp_10, 2014
… Phosphorylation of Akt1 (the protein anabolic marker) was also increased 3.5- to 6.6- fold at ≥ 2 h while total Akt1 expression was not changed over the CEL treatment. …
NAID 130004956850

Related Pictures

★リンクテーブル★

リンク元	「elaboration」「elaborate」「タンパク同化」「蛋白同化」「蛋白同化性」
拡張検索	「anabolic steroid」「anabolic agent」「anabolic-androgenic steroids」

「elaboration」

　　[★]

n.

念入りに作ること、仕上げること、入念。(文章の)遂行。手の込んでいること、精巧
労作
同化作用、同化

Note that renal parenchymal disease may contribute to hypertension even if the glomerular filtration rate is not greatly reduced, through the excessive elaboration of renin.(PHD.321)

関: anabolic、anabolism、assimilation、assimilatory、construction、elaborate、produce、production、syntheses、synthesis、synthesize、synthetic

「elaborate」

　　[★]

vt.

念入りに作る。精巧に作り上げる。
(食物など)を同化する、(有機化合物を)合成する

Hemolysins, leukocidins, and the like are microbial proteins that can kill phagocytes that are attempting to ingest organisms elaborating these substances.