- 関
- amino acid permease、amino acid transport system
WordNet
- move something or somebody around; usually over long distances
- an exchange of molecules (and their kinetic energy and momentum) across the boundary between adjacent layers of a fluid or across cell membranes
- move while supporting, either in a vehicle or in ones hands or on ones body; "You must carry your camping gear"; "carry the suitcases to the car"; "This train is carrying nuclear waste"; "These pipes carry waste water into the river" (同)carry
- transport commercially (同)send, ship
- street name for lysergic acid diethylamide (同)back breaker, battery-acid, dose, dot, Elvis, loony toons, Lucy in the sky with diamonds, pane, superman, window pane, Zen
- any of various water-soluble compounds having a sour taste and capable of turning litmus red and reacting with a base to form a salt
- having the characteristics of an acid; "an acid reaction"
- a long truck for carrying motor vehicles (同)car transporter
- a crane for moving material with dispatch as in loading and unloading ships
- pertaining to or containing any of a group of organic compounds of nitrogen derived from ammonia (同)aminic
- the radical -NH2 (同)amino_group
PrepTutorEJDIC
- (ある場所からある場所へ)…‘を'『輸送する』,運搬する《+名+from+名+to+名》 / 《文》《受動態で》(…で)…‘を'夢中にする,有頂天にする《+名+with+名》 / 〈罪人〉‘を'流刑にする / 〈U〉輸送,運送,輸送(交通)機関(transportation) / 〈C〉(軍隊や軍需品を運ぶ)輸送船,輸送機
- 酸性の / 酸味のある,すっぱい(sour) / (言葉・態度などが)厳しい,しんらつな / 酸 / すっぱいもの / 《俗》=LSD
- 自動車運搬用大型トラック
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/01/22 13:19:46」(JST)
[Wiki en表示]
Transmembrane amino acid transporter protein |
Identifiers |
Symbol |
Aa_trans |
Pfam |
PF01490 |
InterPro |
IPR013057 |
TCDB |
2.A.18 |
Available protein structures: |
Pfam |
structures |
PDB |
RCSB PDB; PDBe |
PDBsum |
structure summary |
|
An amino acid transporter is a membrane transport protein that transports amino acids. They are mainly of the solute carrier family.
Contents
- 1 Solute carrier family examples
- 2 Human proteins containing this domain
- 3 References
|
Solute carrier family examples
- (1) high affinity glutamate and neutral amino acid transporter[1]
- (3) heavy subunits of heteromeric amino acid transporters[2]
- (7) cationic amino acid transporter/glycoprotein-associated[3]
- (15) proton oligopeptide cotransporter[4]
- (17) vesicular glutamate transporter[5]
- (18) vesicular amine transporter[6]
- (25) some mitochondrial carriers[7]
- (26) multifunctional anion exchanger[8]
- (32) vesicular inhibitory amino acid transporter[9]
- (36) proton-coupled amino acid transporter[10]
- (38) System A & N, sodium-coupled neutral amino acid transporter[11]
VIAAT
Vesicular inhibitory amino acid transporter (VIAAT) is responsible for the storage of GABA and glycine in neuronal synaptic vesicles.[12]
Human proteins containing this domain
ATA2; SLC32A1; SLC36A1; SLC36A2; SLC36A3; SLC36A4; SLC38A1; SLC38A2; SLC38A3; SLC38A4; SLC38A5; SLC38A6;
References
- ^ Kanai Y, Hediger MA (2004). "The glutamate/neutral amino acid transporter family SLC1: molecular, physiological and pharmacological aspects". Pflugers Arch 447 (5): 469–479. doi:10.1007/s00424-003-1146-4. PMID 14530974.
- ^ Palacin M, Kanai Y (2004). "The ancillary proteins of HATs: SLC3 family of amino acid transporters". Pflugers Arch 447 (5): 490–494. doi:10.1007/s00424-003-1062-7. PMID 14770309.
- ^ Verrey F, Closs EI, Wagner CA, Palacin M, Endou H, Kanai Y (2004). "CATs and HATs: the SLC7 family of amino acid transporters". Pflugers Arch 447 (5): 532–542. doi:10.1007/s00424-003-1086-z. PMID 14770310.
- ^ Daniel H, Kottra G (2004). "The proton oligopeptide cotransporter family SLC15 in physiology and pharmacology". Pflugers Arch 447 (5): 610–618. doi:10.1007/s00424-003-1101-4. PMID 12905028.
- ^ Reimer RJ, Edwards RH (2004). "Organic anion transport is the primary function of the SLC17/type I phosphate transporter family". Pflugers Arch 447 (5): 629–635. doi:10.1007/s00424-003-1087-y. PMID 12811560.
- ^ Eiden LE, Schafer MK, Weihe E, Schutz B (2004). "The vesicular amine transporter family (SLC18): amine/proton antiporters required for vesicular accumulation and regulated exocytotic secretion of monoamines and acetylcholine". Pflugers Arch 447 (5): 636–640. doi:10.1007/s00424-003-1100-5. PMID 12827358.
- ^ Palmieri F (2004). "The mitochondrial transporter family (SLC25): physiological and pathological implications". Pflugers Arch 447 (5): 689–709. doi:10.1007/s00424-003-1099-7. PMID 14598172.
- ^ Mount DB, Romero MF (2004). "The SLC26 gene family of multifunctional anion exchangers". Pflugers Arch 447 (5): 710–721. doi:10.1007/s00424-003-1090-3. PMID 12759755.
- ^ Gasnier B (2004). "The SLC32 transporter, a key protein for the synaptic release of inhibitory amino acids". Pflugers Arch 447 (5): 752–755. doi:10.1007/s00424-003-1091-2. PMID 12750892.
- ^ Boll M, Daniel H, Gasnier B (2004). "The SLC36 family: proton-coupled transporters for the absorption of selected amino acids from extracellular and intracellular proteolysis family". Pflugers Arch 447 (5): 776–779. doi:10.1007/s00424-003-1073-4. PMID 12748860.
- ^ Mackenzie B, Erickson JD (2004). "Sodium-coupled neutral amino acid (System N/A) transporters of the SLC38 gene family". Pflugers Arch 447 (5): 784–795. doi:10.1007/s00424-003-1117-9. PMID 12845534.
- ^ [Vesicular Inhibitory Amino Acid Transporter Is Present in Glucagon-Containing Secretory Granules in {alpha}TC6 Cells, Mouse Clonal {alpha}-Cells, and {alpha}-Cells of Islets of Langerhans] Diabetes 52:2066-2074, 2003
UpToDate Contents
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English Journal
- Purinergic Modulation of Spinal Neuroglial Maladaptive Plasticity Following Peripheral Nerve Injury.
- Cirillo G1, Colangelo AM2,3, Berbenni M2,3, Ippolito VM2,3, De Luca C1, Verdesca F1, Savarese L1, Alberghina L2,3, Maggio N4,5, Papa M6,7.
- Molecular neurobiology.Mol Neurobiol.2015 Dec;52(3):1440-57. doi: 10.1007/s12035-014-8943-y. Epub 2014 Oct 29.
- Modulation of spinal reactive gliosis following peripheral nerve injury (PNI) is a promising strategy to restore synaptic homeostasis. Oxidized ATP (OxATP), a nonselective antagonist of purinergic P2X receptors, was found to recover a neuropathic behavior following PNI. We investigated the role of i
- PMID 25352445
- Preclinical evaluation of 2-amino-2-[11C]methyl-butanoic acid as a potential tumor-imaging agent in a mouse model.
- Suzuki C1, Tsuji AB, Kato K, Sudo H, Zhang MR, Saga T.
- Nuclear medicine communications.Nucl Med Commun.2015 Nov;36(11):1107-12. doi: 10.1097/MNM.0000000000000364.
- OBJECTIVE: C-labeled 2-amino-2-methyl-butanoic acid (Iva) was previously reported to provide high tumor uptake; however, the pharmacokinetic properties of C-labeled Iva have not been characterized. In the present study, we evaluated the potential of [C]Iva as a PET probe for tumor imaging.METHODS: [
- PMID 26259115
- Grafted biomembranes containing membrane proteins - the case of the leucine transporter.
- Jagalski V1, Barker RD, Thygesen MB, Gotfryd K, Krüger MB, Shi L, Maric S, Bovet N, Moulin M, Haertlein M, Günther Pomorski T, Loland CJ, Cárdenas M.
- Soft matter.Soft Matter.2015 Oct 21;11(39):7707-11. doi: 10.1039/c5sm01490e. Epub 2015 Sep 1.
- Here, we bind the sodium dependent amino acid transporter on nitrilotriacetic acid/polyethylene glycol functionalized gold sensors in detergents and perform a detergent-lipid exchange with phosphatidylcholine. We characterize the LeuT structure in the adsorbed film by magnetic contrast neutron refle
- PMID 26325086
Japanese Journal
- 甲状腺ホルモン輸送蛋白質 (特集 甲状腺ホルモン代謝--最近の進歩)
- Mutation Analysis ABCC9 Gene in Japanese Patients with Coronary Spastic Angina
- Shibutani Shuji,Osanai Tomohiro,Oya Humie,Sagara Shigeki,Izumiyama Kei,Yamamoto Yuko,Hanada Kenji,Tomita Hirofumi,Okumura Ken
- 弘前醫學 62(1), 27-33, 2011
- … Mice with a targeted disruption of the ATP-binding cassette transporter C9‒ABCC9 gene were developed as an animal model of CSA. … In one CSA patient, we found a single base substitution(G to A)at nucleotide position 126 in exon 21 of the coding region, which was heterozygous and did not cause amino acid substitution(T878T, silent mutation).In the remaining 8 patients, no base substitution wasdetected in the coding region of the ABCC9 gene. …
- NAID 110008425087
Related Links
- An amino acid transporter is a membrane transport protein that transports amino acids. They are mainly of the solute carrier family. Contents. 1 Solute carrier family examples. 1.1 VIAAT. 2 Human proteins containing this domain ...
Related Pictures
★リンクテーブル★
[★]
アミノ酸輸送系、アミノ酸輸送システム
- 関
- amino acid permease、amino acid transporter
[★]
アミノ酸パーミアーゼ
- 関
- amino acid transport system、amino acid transporter
[★]
- 英
- amino acid transporter
- 関
- アミノ酸トランスポーター
[★]
- 英
- amino acid transporter
[★]
小胞抑制性アミノ酸輸送体、小胞抑制性アミノ酸トランスポーター
- 関
- vesicular inhibitory amino acid transport protein、VIAAT
[★]
- 関
- basic amino acid transport system
[★]
- 関
- neutral amino acid transport system
[★]
興奮性アミノ酸トランスポーター1、1型興奮性アミノ酸輸送体
- 関
- EAAT1
[★]
興奮性アミノ酸トランスポーター3、3型興奮性アミノ酸輸送体
- 関
- EAAT3
[★]
- 関
- bring、carriage、carry、convey、delivery、ship、traffic、trafficking、transportation
[★]
トランスポーター
- 関
- translocator、transport protein、transporter protein