代替経路補体C3-C5転換酵素
WordNet
- make complete or perfect; supply what is wanting or form the complement to; "I need some pepper to complement the sweet touch in the soup"
- a complete number or quantity; "a full complement"
- one of a series of enzymes in the blood serum that are part of the immune response
- something added to complete or embellish or make perfect; "a fine wine is a perfect complement to the dinner"; "wild rice was served as an accompaniment to the main dish" (同)accompaniment
- number needed to make up a whole force; "a full complement of workers" (同)full complement
- a word or phrase used to complete a grammatical construction
- either of two parts that mutually complete each other
- pertaining to unconventional choices; "an alternative life style"
- necessitating a choice between mutually exclusive possibilities; "alternative possibilities were neutrality or war"
- the 3rd letter of the Roman alphabet (同)c
- (music) the keynote of the scale of C major
- a general-purpose programing language closely associated with the UNIX operating system
- a trodden path (同)footpath
PrepTutorEJDIC
- (あるものを完全にするため)(…を)補う物(事)《+『of』+『名』》 / 補語(文法で文の成分の一つ) / (必要な)全数,全量;(船の)定員 / …を補足する,補う
- (二つのうち)『どちらかを選ぶべき』,二者択一の / 代わりの / 反体制的な,現在の社会と違った価値体系を持った / 二つのものの一つを選ぶこと,二者択一 / (二者のうち)選ぶべき一方 / 代わりのもの;他にとりうる方法
- carbonの化学記号
- 道,小道(path)
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
English Journal
- Structural basis for the stabilization of the complement alternative pathway C3 convertase by properdin.
- Alcorlo M, Tortajada A, Rodríguez de Córdoba S, Llorca O.SourceCentro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, 28040 Madrid, Spain.
- Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2013 Aug 13;110(33):13504-9. doi: 10.1073/pnas.1309618110. Epub 2013 Jul 30.
- Complement is an essential component of innate immunity. Its activation results in the assembly of unstable protease complexes, denominated C3/C5 convertases, leading to inflammation and lysis. Regulatory proteins inactivate C3/C5 convertases on host surfaces to avoid collateral tissue damage. On pa
- PMID 23901101
- Complement activation by heme as a secondary hit for atypical hemolytic uremic syndrome.
- Frimat M, Tabarin F, Dimitrov JD, Poitou C, Halbwachs-Mecarelli L, Fremeaux-Bacchi V, Roumenina LT.SourceINSERM, Unite Mixte de Recherche en Sante 872, Cordeliers Research Center, 15 rue de l'Ecole de Medecine, Paris, France.
- Blood.Blood.2013 Jul 11;122(2):282-92. doi: 10.1182/blood-2013-03-489245. Epub 2013 May 21.
- Atypical hemolytic uremic syndrome (aHUS) is characterized by genetic and acquired abnormalities of the complement system leading to alternative pathway (AP) overactivation and by glomerular endothelial damage, thrombosis, and mechanical hemolysis. Mutations per se are not sufficient to induce aHUS,
- PMID 23692858
- Sushi domain-containing protein 4 (SUSD4) inhibits complement by disrupting the formation of the classical C3 convertase.
- Holmquist E, Okroj M, Nodin B, Jirström K, Blom AM.SourceDepartment of Laboratory Medicine, Division of Medical Protein Chemistry, Lund University, Malmö, Sweden.
- FASEB journal : official publication of the Federation of American Societies for Experimental Biology.FASEB J.2013 Jun;27(6):2355-66. doi: 10.1096/fj.12-222042. Epub 2013 Mar 12.
- Recently discovered Sushi domain-containing protein 4 (SUSD4) contains several Sushi or complement control protein domains; therefore, we hypothesized that it may act as complement inhibitor. Two isoforms of human SUSD4, fused to the Fc part of human IgG, were recombinantly expressed in Chinese hams
- PMID 23482636
Japanese Journal
- :-With Special Reference to Stabilizing Effect on C3 Convertase (C3bBb) Activity-
- 中西 功
- 日本腎臓学会誌 23(6), 719-732, 1981
- … and C3 hemolytic activity were markedly reduced, while the other complement components activities, especially C5 activity, were within normal limits. … These sera showed high C3 nephritic factor (NeF) activities. … The purpose of this paper is to clarify the effect of NeF on the complemet system focusing the attention to the stabilizing effect of NeF on C3 convertase (C3bBb) activity. …
- NAID 130004168733
Related Links
- Alternative-complement-pathway C3/C5 convertase explanation free. What is Alternative-complement-pathway C3/C5 convertase? Meaning of Alternative-complement-pathway C3/C5 convertase medical term. What does Alternative ...
- Purified Proteins Complement proteins used in the present studies were all purified from normal human plasma. C3 (28, 29), factor B (30), and factor D (31) were isolated as described in the references cited. C5 was isolated as ...
★リンクテーブル★
[★]
- 英
- alternative pathway complement C3-C5 convertase
[★]
- 同
- 補体第三成分 third component of complement
- 関
- 補体、C3a, C3b
- 補体の一つ
- C3は血清中に最も多く存在する
- C3 convertaseによってC3aとC3bを生じる
- C3 convertase活性を持つのは2つ
- 1. C4bC2a (古典的経路)
- 2. C3bBbP (別経路)
[★]
[★]
- 代替の、二者択一の、別の、オルタナティブな、アルタナティブな
- 関
- alternatively、alternatives、otherwise、substitution、surrogate
[★]
- 補って完全にする物、補完物。(免疫)補体
- (必要な)全数、善良
[★]
- 英
- complement 5, complement component 5
- 同
- 補体第五成分 fifth component of complement
- 関
- 補体