WordNet

be a contributing factor; "make things factor into a companys profitability"
any of the numbers (or symbols) that form a product when multiplied together
an independent variable in statistics
anything that contributes causally to a result; "a number of factors determined the outcome"
consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"
a concept whose truth can be proved; "scientific hypotheses are not facts"
a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"
a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"
(genetics) the organic process whereby the DNA sequence in a gene is copied into mRNA; the process whereby a base sequence of messenger RNA is synthesized on a template of complementary DNA
a sound or television recording (e.g., from a broadcast to a tape recording)
something written, especially copied from one medium to another, as a typewritten version of dictation (同)written text

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(…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize
〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行
〈U〉(…を)書き写す(書き直す)こと,(…の)転写,謄写《+of+名》 / 〈C〉写し(書き直し)[たもの] / 〈U〉〈C〉編曲[されたもの] / 〈U〉〈C〉(ラジオ・テレビの)録音(録画)
antipersonnel / (またA.P.)Associated Press

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/12/06 17:45:50」(JST)

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AP-1/DNA complex. Crystallographic structure (PDB 1FOS) of the AP-1 heterodimer comprising c-Fos (cyan) and c-Jun (green) complexed with DNA (brown).

In the field of molecular biology, the activator protein 1 (AP-1) is a transcription factor which is a heterodimeric protein composed of proteins belonging to the c-Fos, c-Jun, ATF and JDP families. It regulates gene expression in response to a variety of stimuli, including cytokines, growth factors, stress, and bacterial and viral infections.^[1] AP-1 in turn controls a number of cellular processes including differentiation, proliferation, and apoptosis.^[2]

AP-1 upregulates transcription of genes containing the TPA DNA response element (TRE; 5'-TGAG/CTCA-3').^[1] AP-1 binds to this DNA sequence via a basic amino acid region, while the dimeric structure is formed by a leucine zipper.^[3]　

Regulome

References

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^ General Introduction
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^ AccessMedicine - Content
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UpToDate Contents

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English Journal

The MAPK-activator protein-1 signaling regulates changes in lung tissue of rat exposed to hypobaric hypoxia.

Singh M1, Yadav S1, Kumar M1, Saxena S1, Saraswat D1, Bansal A1, Singh SB1.
Journal of cellular physiology.J Cell Physiol.2018 Oct;233(10):6851-6865. doi: 10.1002/jcp.26556. Epub 2018 Apr 17.
PMID 29665093

Transcriptomic response and perturbation of toxicity pathways in zebrafish larvae after exposure to graphene quantum dots (GQDs).

Deng S1, Jia PP2, Zhang JH3, Junaid M2, Niu A3, Ma YB3, Fu A4, Pei DS5.
Journal of hazardous materials.J Hazard Mater.2018 Sep 5;357:146-158. doi: 10.1016/j.jhazmat.2018.05.063. Epub 2018 May 29.
PMID 29883909

Stimulation of B-Raf increases c-Jun and c-Fos expression and upregulates AP-1-regulated gene transcription in insulinoma cells.

Langfermann DS1, Rössler OG1, Thiel G2.
Molecular and cellular endocrinology.Mol Cell Endocrinol.2018 Sep 5;472:126-139. doi: 10.1016/j.mce.2017.12.003. Epub 2017 Dec 8.
PMID 29225069

Japanese Journal

Involvement of activated transcriptional process in efficient gene transfection using unmodified and mannose-modified bubble lipoplexes with ultrasound exposure.

Un Keita,Kawakami Shigeru,Higuchi Yuriko,Suzuki Ryo,Maruyama Kazuo,Yamashita Fumiyoshi,Hashida Mitsuru
Journal of controlled release : official journal of the Controlled Release Society 156(3), 355-363, 2011-12-20
… The transcriptional process related to activator protein-1 (AP-1) and nuclear factor-κB (NFκB) was activated by US exposure, and was founded to be involved in enhanced gene expression obtained by gene transfection using unmodified and Man-PEG(2000) bubble lipoplexes with US exposure. …
NAID 120003644378