WordNet

touch a player while he is holding the ball
(sports) the act of touching a player in a game (which changes their status in the game)
a game in which one child chases the others; the one who is caught becomes the next chaser
a label written or printed on paper, cardboard, or plastic that is attached to something to indicate its owner, nature, price, etc. (同)ticket
a label associated with something for the purpose of identification; "semantic tags were attached in order to identify different meanings of the word"
attach a tag or label to; "label these bottles" (同)label, mark
provide with a name or nickname
supply (blank verse or prose) with rhymes
the 20th letter of the Roman alphabet (同)t

PrepTutorEJDIC

(名前・番号・定価などを記した)札,下げ札,荷札 / (服などの)切れて垂れ下がった端;(靴ひもなどの)先金 / (特にラテン語引用句の)きまり文句 / =question tag / …‘に'下げ札をつける / (…に)…‘を'つける,加える《+名+on(to)+名》 / 〈人〉‘に'(…の)レッテルをはる《+名+as+名(形)》 / 人の後にくっついて行く《+along》;(人の)すぐ後について行く《+after(behind)+名》
鬼ごっこ / (野球で)タッチアウトにすること / (鬼ごっこで)〈相手〉‘を'捕まえる / (野球で)〈ランナー〉‘を'タッチアウトにする《+out+名,+名+out》
tritiumの化学記号

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/06/02 21:46:33」(JST)

wiki en

Tumor-associated glycoprotein 72 (TAG-72) is a glycoprotein found on the surface of many cancer cells, including ovary,^{[citation needed]} breast, colon, lung, and pancreatic cancers.^[1]^[2] It is a mucin-like molecule with a molar mass of over 1000 kDa.^[3]

TAG-72 is a tumor marker and can be measured with radioimmunoassays like CA 72-4, which uses the monoclonal antibodies indium (¹¹¹In) satumomab pendetide and iodine (¹²⁵I) minretumomab.^[4]^[5]^[6]^[7]^[8] This assay has a good specificity for gastric cancer, with a correlation to the neoplasia's extension. It is used to identify relapses of the disease and to follow up the treatment.

TAG-72 is also the target of the anti-cancer drugs anatumomab mafenatox and minretumomab.

References

^ TAG-72 antigen entry in the public domain NCI Dictionary of Cancer Terms
^ Scott, Andrew M.; Wolchok, Jedd D.; Old, Lloyd J. (2012). "Antibody therapy of cancer". Nature Reviews Cancer 12 (4): 278. doi:10.1038/nrc3236. PMID 22437872.
^ Sheer, Donald G.; Schlom, J; Cooper, HL (1988). "Purification and Composition of the Human Tumor-associated Glycoprotein (TAG-72) Defined by Monoclonal Antibodies CC49 and B72.3". Cancer Research 48 (23): 6811–6818. PMID 3180090.
^ Louhimo J, Alfthan H, Stenman UH, Haglund C (2004). "Serum HCG beta and CA 72-4 are stronger prognostic factors than CEA, CA 19-9 and CA 242 in pancreatic cancer". Oncology 66 (2): 126–31. doi:10.1159/000077438. PMID 15138364.
^ Louhimo J, Carpelan-Holmström M, Alfthan H, Stenman UH, Järvinen HJ, Haglund C (October 2002). "Serum HCG beta, CA 72-4 and CEA are independent prognostic factors in colorectal cancer". Int. J. Cancer 101 (6): 545–8. doi:10.1002/ijc.90009. PMID 12237895.
^ Louhimo J, Kokkola A, Alfthan H, Stenman UH, Haglund C (October 2004). "Preoperative hCGbeta and CA 72-4 are prognostic factors in gastric cancer". Int. J. Cancer 111 (6): 929–33. doi:10.1002/ijc.20321. PMID 15300805.
^ Mattar R, Alves de Andrade CR, DiFavero GM, Gama-Rodrigues JJ, Laudanna AA (2002). "Preoperative serum levels of CA 72-4, CEA, CA 19-9, and alpha-fetoprotein in patients with gastric cancer". Rev Hosp Clin Fac Med Sao Paulo 57 (3): 89–92. doi:10.1590/s0041-87812002000300001. PMID 12118264.
^ Guadagni F, Roselli M, Cosimelli M, et al. (November 1996). "Correlation between tumor-associated glycoprotein 72 mucin levels in tumor and serum of colorectal patients as measured by the quantitative CA 72-4 immunoassay". Cancer Res. 56 (22): 5293–8. PMID 8912871.

This article incorporates public domain material from the U.S. National Cancer Institute document "Dictionary of Cancer Terms".

This oncology article is a stub. You can help Wikipedia by expanding it.

UpToDate Contents

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1. 乳児血管腫：疫学、発症機序、臨床的特徴、合併症 infantile hemangiomas epidemiology pathogenesis clinical features and complications
2. 胸部大動脈修復術のための血管内デバイス endovascular devices for thoracic aortic repair
3. 糖尿病症例解説7：2型糖尿病、消化管出血および複数の医学的問題を有する72歳男性における糖尿病管理 interactive diabetes case 7 management of diabetes in a 72 year old man with type 2 diabetes gi bleeding and multiple other medical problems
4. 手術における血液保存：術前自己血輸血 surgical blood conservation preoperative autologous blood donation
5. 痔疾患の外科的治療 surgical treatment of hemorrhoidal disease

English Journal

Development of Rous sarcoma Virus-like Particles Displaying hCC49 scFv for Specific Targeted Drug Delivery to Human Colon Carcinoma Cells.

Kato T1,2,3, Yui M1, Deo VK2, Park EY4,5,6.
Pharmaceutical research.Pharm Res.2015 Nov;32(11):3699-707. doi: 10.1007/s11095-015-1730-2. Epub 2015 Jun 6.
PURPOSE: Virus-like particles (VLPs) have been used as drug carriers for drug delivery systems. In this study, hCC49 single chain fragment variable (scFv)-displaying Rous sarcoma virus-like particles (RSV VLPs) were produced in silkworm larvae to be a specific carrier of an anti-cancer drug.METHOD:
PMID 26047779

Prognostic value of preoperative Ca125 and Tag72 serum levels and their correlation to disease relapse and survival in endometrial cancer.

Myriokefalitaki E1, Vorgias G, Vlahos G, Rodolakis A.
Archives of gynecology and obstetrics.Arch Gynecol Obstet.2015 Sep;292(3):647-54. doi: 10.1007/s00404-015-3675-4. Epub 2015 Mar 3.
OBJECTIVE: To evaluate preoperative serum levels of Ca125 and Tag72-4 tumour markers and investigate if abnormal levels correlate to mortality and disease-free survival.METHOD: Retrospective observational study of a cohort of 282 women (mean age 62.3, SD 10.5 years) with primary endometrial cancer i
PMID 25731151

Japanese Journal

CA72-4(TAG72) (広範囲血液・尿化学検査免疫学的検査(第7版・4)その数値をどう読むか) -- (腫瘍マーカー)

水本泰成,京哲,高倉正博 [他]
日本臨床 68(-) (982), 717-719, 2010-07
NAID 40017200850

Enzyme-linked immunosorbent assay-based selection and optimization of elution buffer for TAG72-affinity chromatography

YANG Junbao,MOYANA Terence,XIANG Jim
Journal of chromatography. B, Biomedical sciences and applications 731(2), 299-308, 1999-08-27
NAID 10024539720

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