WordNet
- be a contributing factor; "make things factor into a companys profitability"
- any of the numbers (or symbols) that form a product when multiplied together
- an independent variable in statistics
- anything that contributes causally to a result; "a number of factors determined the outcome"
- consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
- resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
- an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"
- a concept whose truth can be proved; "scientific hypotheses are not facts"
- a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"
- a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"
- (genetics) the organic process whereby the DNA sequence in a gene is copied into mRNA; the process whereby a base sequence of messenger RNA is synthesized on a template of complementary DNA
- a sound or television recording (e.g., from a broadcast to a tape recording)
- something written, especially copied from one medium to another, as a typewritten version of dictation (同)written text
PrepTutorEJDIC
- (…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize
- 〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行
- 〈U〉(…を)書き写す(書き直す)こと,(…の)転写,謄写《+of+名》 / 〈C〉写し(書き直し)[たもの] / 〈U〉〈C〉編曲[されたもの] / 〈U〉〈C〉(ラジオ・テレビの)録音(録画)
UpToDate Contents
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- 1. 抗酸菌易感染性を示すメンデル型遺伝性疾患（Mendelian
susceptibility to mycobacterial
diseases：MSMD） mendelian susceptibility to mycobacterial diseases msmd - 2. 骨髄造血の制御 regulation of myelopoiesis
- 3. サルコイドーシスの病因 pathogenesis of sarcoidosis
- 4. 慢性関節リウマチにおける滑膜異常 synovial pathology in rheumatoid arthritis
- 5. ヘルパーT細胞サブセット：疾患における分化および役割 t helper subsets differentiation and role in disease
English Journal
- JAK1/STAT3 activation directly inhibits IL-12 production in dendritic cells by preventing CDK9/P-TEFb recruitment to the p35 promoter.
- Wagner AH1, Conzelmann M2, Fitzer F3, Giese T4, Gülow K5, Falk CS6, Krämer OH7, Dietrich S2, Hecker M3, Luft T2.
- Biochemical pharmacology.Biochem Pharmacol.2015 Jul 1;96(1):52-64. doi: 10.1016/j.bcp.2015.04.019. Epub 2015 Apr 28.
- Inhibition of Janus-activated kinase-1 (JAK1) is a promising clinical concept for post-transplant immunosuppression and autoimmunity. However, it also raises concerns regarding possible immunosuppressive side effects. Our study investigates JAK1 signalling in the context of CD40L and bacterially act
- PMID 25931145
- Noncanonical Effects of IRF9 in Intestinal Inflammation: More than Type I and Type III Interferons.
- Rauch I1, Rosebrock F1, Hainzl E2, Heider S3, Majoros A1, Wienerroither S1, Strobl B2, Stockinger S2, Kenner L3, Müller M2, Decker T4.
- Molecular and cellular biology.Mol Cell Biol.2015 Jul 1;35(13):2332-43. doi: 10.1128/MCB.01498-14. Epub 2015 Apr 27.
- The interferon (IFN)-stimulated gene factor 3 (ISGF3) transcription factor with its Stat1, Stat2, and interferon regulatory factor 9 (IRF9) subunits is employed for transcriptional responses downstream of receptors for type I interferons (IFN-I) that include IFN-α and IFN-β and type III interferon
- PMID 25918247
- Analysis of DNA methylation and gene expression in radiation-resistant head and neck tumors.
- Chen X1, Liu L, Mims J, Punska EC, Williams KE, Zhao W, Arcaro KF, Tsang AW, Zhou X, Furdui CM.
- Epigenetics : official journal of the DNA Methylation Society.Epigenetics.2015 Jun 3;10(6):545-61. doi: 10.1080/15592294.2015.1048953.
- Resistance to radiation therapy constitutes a significant challenge in the treatment of head and neck squamous cell cancer (HNSCC). Alteration in DNA methylation is thought to play a role in this resistance. Here, we analyzed DNA methylation changes in a matched model of radiation resistance for HNS
- PMID 25961636
Japanese Journal
- Anti-inflammatory Actions of Herbal Formula Gyejibokryeong-Hwan Regulated by Inhibiting Chemokine Production and STAT1 Activation in HaCaT Cells
- , , [他], , , ,
- Biological and Pharmaceutical Bulletin 38(3), 425-434, 2015
- … Exposure to the proinflammatory cytokines tumor necrosis factor-alpha (TNF-α) and interferon-gamma (IFN-γ) significantly increased HaCaT cell production of the following chemokines: macrophage-derived chemokine (MDC)/CCL22; … Treatment with GJBRH markedly inhibited phosphorylation of signal transducer and activator of transcription 1 (STAT1) in HaCaT cells stimulated with TNF-α and IFN-γ. …
- NAID 130004872285
- Newly Synthesized 'Hidabeni' Chalcone Derivatives Potently Suppress LPS-Induced NO Production via Inhibition of STAT1, but Not NF-κB, JNK, and p38, Pathways in Microglia
- , , , , ,
- Biological and Pharmaceutical Bulletin 37(6), 1042-1049, 2014
- … C4 and C10 suppressed LPS-induced iNOS expression via the inhibition of the signal transduction and activator of transcription 1 (STAT1), but not nuclear factor-kappa B (NF-κB), c-Jun N terminal kinase (JNK), and p38, pathways. … C4 and C10 also suppressed LPS-induced expression of interferon regulatory factor 1 (IRF-1), which is an important transcription factor involved in iNOS expression. …
- NAID 130004147351
- Methyl 5-Chloro-4,5-didehydrojasmonate (J7) Inhibits Macrophage-Derived Chemokine Production via Down-Regulation of the Signal Transducers and Activators of Transcription 1 Pathway in HaCaT Human Keratinocytes
- , , , , , , , , ,
- Chemical and Pharmaceutical Bulletin 61(10), 1002-1008, 2013
- … The current study therefore investigated the impact of jasmonate derivatives (jasmonic acid and methyl jasmonate) and their synthetic analogues (J2 and J7) on the expression of MDC in interferon (IFN)-γ- and tumor necrosis factor (TNF)-α-stimulated HaCaT human keratinocytes, as well as the attendant mechanism of action. …
- NAID 130004137254
Related Links
- "STAT1 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). ... A signal transducer and activator of transcription that mediates cellular ...
- "STAT1 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). ... A signal transducer and activator of transcription that mediates cellular ...
Related Pictures
★リンクテーブル★
| リンク元 | 「STAT1転写因子」 |
| 関連記事 | 「fact」「factor」「transcription factor」「STA」「STAT」 |
「STAT1転写因子」
- STAT2やIRF-9と複合体を形成しIFN発現を誘導する転写因子
「fact」
- n.
「factor」
- n.