WordNet
- the rotating armature of a motor or generator (同)rotor coil
- rotating mechanism consisting of an assembly of rotating airfoils; "there are horizontal rotors on a helicopter or compressor rotors in a jet engine"
- the revolving bar of a distributor
- a pattern of symptoms indicative of some disease
- a complex of concurrent things; "every word has a syndrome of meanings"
PrepTutorEJDIC
- (電動機などの)回転子 / (ヘリコプターなどの)回転翼
- (疾患の徴候となる一群の)症徴候,症候群 / (事件・社会的状態などのパターンを示す)徴候形態
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/11/07 05:23:54」(JST)
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- 1. 抱合型高ビリルビン血症関連の遺伝性疾患 inherited disorders associated with conjugated hyperbilirubinemia
- 2. 肝酵素および肝機能検査値の異常が認められた患者に対するアプローチ approach to the patient with abnormal liver biochemical and function tests
- 3. 黄疸または無症候性高ビリルビン血症成人患者に対する診断的アプローチ diagnostic approach to the adult with jaundice or asymptomatic hyperbilirubinemia
- 4. 黄疸または無症候性高ビリルビン血症の分類および原因 classification and causes of jaundice or asymptomatic hyperbilirubinemia
- 5. 心房細動再発予防のためのカテーテルアブレーション：技術的事項 catheter ablation to prevent recurrent atrial fibrillation technical considerations
English Journal
- Management of a patient with colon cancer and rotor syndrome: A case report.
- Arslan D, Avci F, Merdin A, Gunduz S, Coskun HS.Author information Department of Medical Oncology, Akdeniz University Faculty of Medicine, Antalya 07070, Turkey.AbstractRotor Syndrome (RS) is a rare disease that is autosomal recessive and characterized by asymptomatic jaundice, conjugated hyperbilirubinemia and coproporphyria. RS occurs as a result of a complete lack or partial defect of organic anion transporter polypeptides (OATPs) on the basolateral surface of hepatocytes. OATPs facilitate the excretion of bilirubin and organic anions from the liver to the bile. To the best of our knowledge, there is no information in the literature relating to the treatment of a patient with colon cancer and RS. The present study aimed to discuss the systematic chemotherapy that is used and the effects on a 45-year-old patient who had RS with asymptomatic jaundice and was diagnosed with colon adenocarcinoma following surgery. The patient was administered oxaliplatin in combination with capecitabine. The patient's biluribin level increased after one week. Capecitabine treatment was interrupted and the patient was administered oxaliplatin monotherapy. No significant toxicity was observed during that period. At the latest follow-up the patient did not exhibit any progression.
- Oncology letters.Oncol Lett.2014 Mar;7(3):797-798. Epub 2013 Dec 19.
- Rotor Syndrome (RS) is a rare disease that is autosomal recessive and characterized by asymptomatic jaundice, conjugated hyperbilirubinemia and coproporphyria. RS occurs as a result of a complete lack or partial defect of organic anion transporter polypeptides (OATPs) on the basolateral surface of h
- PMID 24520296
- Variations in both α-spectrin (SPTA1) and β-spectrin ( SPTB ) in a neonate with prolonged jaundice in a family where nine individuals had hereditary elliptocytosis.
- Christensen RD, Nussenzveig RH, Reading NS, Agarwal AM, Prchal JT, Yaish HM.Author information Department of Women and Newborns, Intermountain Healthcare, Salt Lake City, Utah, USA.AbstractWe cared for a neonate who had problematic hyperbilirubinemia born into a family where nine first-degree relatives had hereditary elliptocytosis (HE). As neonates, the nine relatives did not have any significant jaundice or anemia that was recognizable. Blood films on the proband suggested a diagnosis of pyropoikilocytosis. Analysis of the α-spectrin gene (SPTA1) in the proband revealed two previously reported low-frequency heterozygous polymorphisms of unknown clinical significance and the α(LELY) allele. In addition, a novel heterozygous mutation was identified in exon 2 of the β-spectrin gene SPTB. No mutations were identified in ANK1 (ankyrin-1), SLC4A1 (band 3), EPB41 (band 4.1), or EPB42 (band 4.2).
- Neonatology.Neonatology.2014;105(1):1-4. doi: 10.1159/000354884. Epub 2013 Oct 31.
- We cared for a neonate who had problematic hyperbilirubinemia born into a family where nine first-degree relatives had hereditary elliptocytosis (HE). As neonates, the nine relatives did not have any significant jaundice or anemia that was recognizable. Blood films on the proband suggested a diagnos
- PMID 24193021
- Cardiac Arrythmias: Multimodal Assessment Integrating Body Surface ECG Mapping into Cardiac Imaging.
- Cochet H, Dubois R, Sacher F, Derval N, Sermesant M, Hocini M, Montaudon M, Haïssaguerre M, Laurent F, Jaïs P.Author information From the Departments of Cardiovascular Imaging (H.C., M.M., F.L.) and Cardiac Pacing and Electrophysiology (F.S., N.D., M. Hocini, M. Haïssaguerre, P.J.), Centre Hospitalier Universitaire/Université de Bordeaux, Hopital Cardiologique Haut Lévêque, Avenue de Magellan, 33604 Pessac, France; L'Institut de Rythmologie et de Modélisation Cardiaque-Equipex Multimodal Platform for Specific Imaging in Cardiology, Centre Hospitalier Universitaire/Université de Bordeaux/Institut National de la Santé et de la Recherche Médicale U1045, Pessac, France (H.C., R.D., F.S., N.D., M.H., M.M., M.H., F.L., P.J.); and Institut National de Recherche en Informatique et Automatique Asclepios Research Team-Institut National de Recherche en Informatique et Automatique Sophia Antipolis, Sophia Antipolis, France (M.S.).AbstractPurpose To demonstrate the feasibility of comprehensive assessment of cardiac arrhythmias by combining body surface electrocardiographic (ECG) mapping (BSM) and imaging. Materials and Methods This study was approved by the institutional review board, and all patients gave written informed consent. Twenty-seven patients referred for electrophysiologic procedures in the context of ventricular tachycardia (VT) (n = 9), Wolff-Parkinson-White (WPW) syndrome (n = 2), atrial fibrillation (AF) (n = 13), or scar-related ventricular fibrillation (VF) (n = 3) were examined. Patients underwent BSM and imaging with multidetector computed tomography (CT) (n = 12) and/or delayed enhanced magnetic resonance (MR) imaging (n = 23). BSM was performed by using a 252-electrode vest that enabled the computation of epicardial electrograms from body surface potentials. The epicardial geometry used for BSM was registered to the epicardial geometry segmented from imaging data by using an automatic algorithm. The output was a three-dimensional (3D) cardiac model that integrated cardiac anatomy, myocardial substrate, and epicardial activation. Results Acquisition, segmentation, and registration were feasible in all patients. In VT, this enabled a noninvasive assessment of the arrhythmia mechanism and its location with respect to the myocardial substrate, coronary vessels, and phrenic nerve. In WPW syndrome, this enabled understanding of complex accessory pathways resistant to previous ablation. In AF and VF, this enabled the noninvasive assessment of arrhythmia mechanisms and the analysis of rotor trajectories with respect to the myocardial substrate. In all patients, 3D models were successfully integrated in navigation systems and used to guide mapping and ablation. Conclusion By combining information on anatomy, substrate, and electrical activation, the fusion of BSM and imaging enables comprehensive noninvasive assessment of cardiac arrhythmias, with potential applications for diagnosis, prognosis, and ablation targeting. © RSNA, 2013 Online supplemental material is available for this article.
- Radiology.Radiology.2013 Dec 3:131331. [Epub ahead of print]
- Purpose To demonstrate the feasibility of comprehensive assessment of cardiac arrhythmias by combining body surface electrocardiographic (ECG) mapping (BSM) and imaging. Materials and Methods This study was approved by the institutional review board, and all patients gave written informed consent. T
- PMID 24475841
Japanese Journal
- Activation Pattern of the Polymorphic Ventricular Tachycardia and Ventricular Fibrillation on Body Surface Mapping in Patients With Brugada Syndrome
- Circulation Journal 80(8), 1734-1743, 2016
- NAID 130005166108
- Activation Pattern of the Polymorphic Ventricular Tachycardia and Ventricular Fibrillation on Body Surface Mapping in Patients With Brugada Syndrome
- Circulation Journal advpub(0), 2016
- NAID 130005157750
- 357 自己同期現象を利用した振動ランマの開発 : 試作機の性能評価(領域1 解析・設計の高度化と新展開)
- 機械力学・計測制御講演論文集 2014, "357-1"-"357-9", 2014-08-25
- NAID 110009979329
Related Links
- Rotor syndrome, also called Rotor type hyperbilirubinemia, is a rare, relatively benign autosomal recessive bilirubin disorder of unknown origin. It is a distinct disorder, yet similar to Dubin–Johnson syndrome — both diseases cause an ...
Related Pictures
★リンクテーブル★
| リンク元 | 「ローター症候群」「RS」「hereditary hyperbilirubinemia」 |
| 関連記事 | 「rotor」「syndrome」 |
「ローター症候群」
- 英
- Rotor syndrome RS
- 同
- (国試)Rotor症候群、ローター型高ビリルビン血症 Rotor hyperbilirubinemia、Rotor型過ビリルビン血症
- 関
- 黄疸、高直接ビリルビン血症
概念
- 軽度の直接ビリルビン血症を呈する疾患で体質黄疸の一つである。
検査
- HIM.1913 参考1
- 間接ビリルビン：軽度高値
- 肝機能：正常
- 肝臓表面の外観：正常 ⇔ デュビン・ジョンソン症候群は黒色肝を呈する
- ブロムスルファレイン試験：BPSの血中停滞率が異常に上昇(すなわち排泄が遅延)する → 抱合化されたBPSを肝細胞内にとどめておく機構が障害を受けているという仮説が立てられている(HIM.1931)
- コポルフィリンI：胆汁に多く含まれて排泄されるが、本疾患では体循環に逆流し尿中に排泄される ⇔ デュビン・ジョンソン症候群では尿中コポルフィリンI排泄は正常
- 経口胆嚢造影：胆嚢が造影される ⇔ デュビン・ジョンソン症候群では造影されない
参考
- 1. [charged] Inherited disorders associated with conjugated hyperbilirubinemia - uptodate [1]
体質性黄疸 (IMD.875)
| 体質性黄疸 | 遺伝形式* | ビリルビン型 | ビリルビン値 | 予後 |
| Crigler-Najjar症候群I型 | 常染色体劣性 | 間接型(非抱合) | 21-31mg/dl | 致死的 |
| Crigler-Najjar症候群II型 | 常染色体劣性 | 8-18mg/dl | 良好 | |
| Gilbert症候群 | 常染色体優性 | <6mg/dl | きわめて良好 | |
| Dubin-Johnson症候群 | 常染色体劣性 | 直接型(抱合) | 2-5(-25)mg/dl | きわめて良好 |
| Rotor症候群 | 常染色体劣性 | 2-5(-20)mg/dl | きわめて良好 | |
| *劣性か優性かについては例外あり | ||||
「RS」
「hereditary hyperbilirubinemia」
「rotor」
「syndrome」
- n.