プラスミノゲン
WordNet
- the 16th letter of the Roman alphabet (同)p
PrepTutorEJDIC
- parking
- phosphorusの化学記号
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/09/26 11:46:14」(JST)
[Wiki en表示]
PLG may stand for:
- Parti Libéral Genevois (Liberal Party of Geneva)
- Plasminogen
- Pierre-Luc Gagnon, a professional skateboarder
- Paul Le Guen, French football manager
- Polynesian Leaders Group, a regional inter-governmental grouping in Polynesia
- Progressive Librarians Guild a Librarian Organisation
- Prospect Lefferts Gardens, a neighborhood bordering Prospect Park in Brooklyn, New York
- Provident Label Group, a division of Sony Music Entertainment focusing primarily on Christian music
UpToDate Contents
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- 1. 肺リンパ腫様肉芽腫症 pulmonary lymphomatoid granulomatosis
English Journal
- Plasmin Deficiency Leads to Fibrin Accumulation and a Compromised Inflammatory Response in the Mouse Brain.
- Hultman K1, Cortes-Canteli M, Bounoutas A, Richards AT, Strickland S, Norris EH.Author information 1The Rockefeller University, New York, NY, 10065.AbstractBACKGROUND: Excess fibrin in blood vessels is cleared by plasmin, the key proteolytic enzyme in fibrinolysis. Neurological disorders and head trauma can result in the disruption of the neurovasculature and the entry of fibrin and other blood components into the brain, which may contribute to further neurological dysfunction.
- Journal of thrombosis and haemostasis : JTH.J Thromb Haemost.2014 Mar 10. doi: 10.1111/jth.12553. [Epub ahead of print]
- BACKGROUND: Excess fibrin in blood vessels is cleared by plasmin, the key proteolytic enzyme in fibrinolysis. Neurological disorders and head trauma can result in the disruption of the neurovasculature and the entry of fibrin and other blood components into the brain, which may contribute to further
- PMID 24612416
- Pneumococcal phosphoglycerate kinase interacts with plasminogen and its tissue activator.
- Fulde M, Bernardo-García N, Rohde M, Nachtigall N, Frank R, Preissner KT, Klett J, Morreale A, Chhatwal GS, Hermoso JA, Bergmann S1.Author information 1Simone Bergmann, PhD, Technische Universität Braunschweig, Spielmannstrasse 7, 38106 Braunschweig, Germany, Tel.: +49 531 391 5818, Fax: +49 531 391 5854, E-mail: simone.bergmann@tu-bs.de.AbstractStreptococcus pneumoniae is not only a commensal of the nasopharyngeal epithelium, but may also cause life-threatening diseases. Immune-electron microscopy studies revealed that the bacterial glycolytic enzyme, phosphoglycerate kinase (PGK), is localised on the pneumococcal surface of both capsulated and non-capsulated strains and colocalises with plasminogen. Since pneumococci may concentrate host plasminogen (PLG) together with its activators on the bacterial cell surface to facilitate the formation of plasmin, the involvement of PGK in this process was studied. Specific binding of human or murine PLG to strain-independent PGK was documented, and surface plasmon resonance analyses indicated a high affinity interaction with the kringle domains 1-4 of PLG. Crystal structure determination of pneumococcal PGK together with peptide array analysis revealed localisation of PLG-binding site in the N-terminal region and provided structural motifs for the interaction with PLG. Based on structural analysis data, a potential interaction of PGK with tissue plasminogen activator (tPA) was proposed and experimentally confirmed by binding studies, plasmin activity assays and thrombus degradation analyses.
- Thrombosis and haemostasis.Thromb Haemost.2014 Mar 3;111(3):401-16. doi: 10.1160/TH13-05-0421. Epub 2013 Nov 7.
- Streptococcus pneumoniae is not only a commensal of the nasopharyngeal epithelium, but may also cause life-threatening diseases. Immune-electron microscopy studies revealed that the bacterial glycolytic enzyme, phosphoglycerate kinase (PGK), is localised on the pneumococcal surface of both capsulate
- PMID 24196407
- Anti-tumor efficacy of c(RGDfK)-decorated polypeptide-based micelles co-loaded with docetaxel and cisplatin.
- Song W1, Tang Z2, Zhang D1, Zhang Y1, Yu H1, Li M3, Lv S3, Sun H1, Deng M4, Chen X1.Author information 1Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, PR China.2Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, PR China. Electronic address: ztang@ciac.ac.cn.3Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, PR China; University of Chinese Academy of Sciences, Beijing 100039, PR China.4Department of Chemistry, Northeast Normal University, Changchun 130021, PR China.AbstractThere are two important obstacles for the currently applied anti-cancer drug delivery systems. One is the conflict between long-circulation and cellular uptake while the other one is the achievement of ideal anti-cancer efficacy. To solve these problems, we designed a polypeptide-based micelle system that combined the advantages of receptor mediated endocytosis and multi-drug delivery. Firstly, an amphiphilic PLG-g-Ve/PEG graft copolymer was prepared by grafting α-tocopherol (Ve) and polyethylene glycol (PEG) to poly(l-glutamic acid) (PLG). Then docetaxel (DTX) and cisplatin (CDDP) were co-loaded into the PLG-g-Ve/PEG micelles via hydrophobic and chelation effect. After that, the surface of the dual-drug-loaded micelles was decorated with an αvβ3 integrin targeting peptide c(RGDfK). The targeted dual-drug-loaded micelles showed synergistic cytotoxicity and enhanced internalization rate in mouse melanoma (B16F1) cells. In vivo tests demonstrated that remarkable long circulation, anti-tumor and anti-metastasis efficacy could be achieved using this drug delivery system. This work revealed a strategy for the design and preparation of anti-cancer drug delivery systems with reduced side effect, enhanced anti-tumor and anti-metastasis efficacy.
- Biomaterials.Biomaterials.2014 Mar;35(9):3005-14. doi: 10.1016/j.biomaterials.2013.12.018. Epub 2014 Jan 2.
- There are two important obstacles for the currently applied anti-cancer drug delivery systems. One is the conflict between long-circulation and cellular uptake while the other one is the achievement of ideal anti-cancer efficacy. To solve these problems, we designed a polypeptide-based micelle syste
- PMID 24388813
Japanese Journal
- PLG方式地上コイルのケーブル配線施工性検証 (特集 浮上式鉄道技術と在来方式鉄道への応用)
- ポリ乳酸 • グリコール酸( PLG )スカフォールドを使用した家兎肩腱板再生の試み
- 乾 淳幸,国分 毅,坂田 亮介,美舩 泰,無藤 智之,藤岡 宏幸
- 肩関節 36(3), 913-916, 2012
- … We created a novel poly (D-L-lactide-co-glycolide) (PLG) scaffold using the electrospinning method and evaluated its application in a rabbit rotator cuff defect model.<BR><B>Methods:</B> … Defects of the infraspinatus tendon were created and the PLG scaffolds were implanted. … At 8 weeks, the PLG scaffold had dissolved and bone formation was observed at the scaffold-bone interface. …
- NAID 130002103562
Related Links
- プレミアムリンクジェネレーターのサイトをまとめました。基本無料ですが、VIP会員の制度があるサイトもございます。各サイトは使用確認はしておりますが、リンク切れは...
- 2015/11/26 (Thu) Turkdown.com(タークダウンドットコム)は、トルコの自立型PLGです。ここは前にご紹介しました「CBox TurkDown.com」と運営元が同じです。名前も似てますね。トルコのPLGは、自立型とCBox型を両方運営する例がいくつか ...
Related Pictures
★リンクテーブル★
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- 英
- plasminogen Plg PLG
- 同
- プラスミノーゲン
[show details]
- 肝臓で生成される
- プラスミノゲンが活性化因子によりプラスミンとなる
活性化因子
-プラスミノーゲン
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蛋白漏出性胃腸疾患 protein-losing gastroenteropathy
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- PL配合顆粒
- 総合感冒剤/鎮咳,抗ヒスタミン,解熱配合剤/総合感冒剤
参考
http://www.interq.or.jp/ox/dwm/se/se11/se1180107.html
http://www.info.pmda.go.jp/go/pack/1180107D1131_1_02/
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