WordNet

direct the flow of; "channel information towards a broad audience" (同)canalize, canalise
a television station and its programs; "a satellite TV channel"; "surfing through the channels"; "they offer more than one hundred channels" (同)television channel, TV channel
a passage for water (or other fluids) to flow through; "the fields were crossed with irrigation channels"; "gutters carried off the rainwater into a series of channels under the street"
(often plural) a means of communication or access; "it must go through official channels"; "lines of communication were set up between the two firms" (同)communication channel, line
a path over which electrical signals can pass; "a channel is typically what you rent from a telephone company" (同)transmission channel
a deep and relatively narrow body of water (as in a river or a harbor or a strait linking two larger bodies) that allows the best passage for vessels; "the ship went aground in the channel"
write by means of a keyboard with types; "type the acceptance letter, please" (同)typewrite
a small metal block bearing a raised character on one end; produces a printed character when inked and pressed on paper; "he dropped a case of type, so they made him pick them up"
(biology) the taxonomic group whose characteristics are used to define the next higher taxon
a subdivision of a particular kind of thing; "what type of sculpture do you prefer?"
all of the tokens of the same symbol; "the word `element contains five different types of character"
printed characters; "small type is hard to read"
identify as belonging to a certain type; "Such people can practically be typed" (同)typecast
relying on or requiring a person or thing for support, supply, or what is needed; "dependent children"; "dependent on moisture"
addicted to a drug (同)dependant, drug-addicted, hooked, strung-out
contingent on something else (同)dependant, qualified
(of a clause) unable to stand alone syntactically as a complete sentence; "a subordinate (or dependent) clause functions as a noun or adjective or adverb within a sentence" (同)subordinate
the rate at which energy is drawn from a source that produces a flow of electricity in a circuit; expressed in volts (同)electromotive_force, emf
a white metallic element that burns with a brilliant light; the fifth most abundant element in the earths crust; an important component of most plants and animals (同)Ca, atomic number 20

PrepTutorEJDIC

〈C〉『水路』(川・湾・運河の船の通行ができる深い部分) / 〈U〉河床・川底 / 〈C〉『海峡』 / 〈C〉みぞ(groove),(道路の)水渠(すいきょ) / 《複数形で》(運搬・伝達の)正式の経路(手続き);(一般に)経路 / 〈C〉(テレビ・ラジオの)チャンネル / …‘に'水路を開く / …‘に'みぞを堀る / …'を'伝える,流す
〈C〉(…の)『型』,タイプ,類型,種類(kind)《+of+名》 / 〈C〉(その種類の特質を最もよく表している)『典型』,手本,模範《+of+名》 / 〈U〉《集合的に》活字;〈C〉(1個の)活字 / 〈U〉(印刷された)字体,活字 / 〈C〉(貨幣・メダルなどの)模様,図柄 / 〈C〉血液型(blood group) / …‘を'タイプに打つ / (…として)…‘を'分類する《+名+as+名(doing)》 / …‘の'型を決める / タイプライターを打つ
『頼っている』,依存している,従属している / 扶養される人(家族)
電圧,電圧量,ボルト数
『カルシウム』(金属元素;化学記号は『Ca』)

UpToDate Contents

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1. Lambert-Eaton筋無力症候群の臨床的特徴および診断 clinical features and diagnosis of lambert eaton myasthenic syndrome
2. 脊髄小脳変性症 the spinocerebellar ataxias
3. 遺伝性運動失調の概要 overview of the hereditary ataxias
4. 抗てんかん剤：作用機序、薬理学、および有害事象 antiepileptic drugs mechanism of action pharmacology and adverse effects
5. 心筋活動電位および抗不整脈剤の作用 myocardial action potential and action of antiarrhythmic drugs

English Journal

ZC88, a novel N-type calcium channel blocker from 4-amino-piperidine derivatives state-dependent inhibits Cav2.2 calcium channels.

Zhang S1, Yang L2, Zhang K1, Liu X1, Dai W1, Zhang C1, Yong Z1, Li J3, Zheng J4.
Brain research.Brain Res.2015 Apr 24;1605:12-21. doi: 10.1016/j.brainres.2015.01.054. Epub 2015 Feb 12.
Small molecular inhibitors of Cav2.2 have been reported for the treatment of neuropathic pain; however, low selectivity and side effects limit their further development. In our study, a series of new compounds were designed and synthesized by optimizing the 4-amino-piperidine template. The results s
PMID 25681549

Methamphetamine blunts Ca2+ currents and excitatory synaptic transmission through D1/5 receptor-mediated mechanisms in the mouse medial prefrontal cortex.

González B1, Rivero-Echeto C, Muñiz JA, Cadet JL, García-Rill E, Urbano FJ, Bisagno V.
Addiction biology.Addict Biol.2015 Apr 14. doi: 10.1111/adb.12249. [Epub ahead of print]
Psychostimulant addiction is associated with dysfunctions in frontal cortex. Previous data demonstrated that repeated exposure to methamphetamine (METH) can alter prefrontal cortex (PFC)-dependent functions. Here, we show that withdrawal from repetitive non-contingent METH administration (7 days, 1�
PMID 25871318

Cacna1c (Cav1.2) Modulates Electroencephalographic Rhythm and Rapid Eye Movement Sleep Recovery.

Kumar D, Dedic N, Flachskamm C, Voulé S, Deussing JM, Kimura M.
Sleep.Sleep.2015 Feb 25. pii: sp-00632-14. [Epub ahead of print]
Study Objectives: The CACNA1C gene encodes the alpha 1C (α1C) subunit of the Cav1.2 voltage-dependent L-type calcium channel (LTCC). Some of the other voltage-dependent calcium channels, e.g., P-/Q-type, Cav2.1; N-type, Cav2.2; E-/R-type, Cav2.3; and T-type, Cav3.3 have been implicated in sleep mod
PMID 25845695

Japanese Journal

T-Type Ca Channel Blockade as a Determinant of Kidney Protection

HAYASHI Koichi,HOMMA Koichiro,WAKINO Shu,TOKUYAMA Hirobumi,SUGANO Naoki,SARUTA Takao,ITOH Hiroshi
Keio journal of medicine 59(3), 84-95, 2010-09-01
… Voltage-dependent Ca channels are classified into several subtypes based on the isoform of their α1 subunits. … Traditional Ca channels blockers (CCBs), including nifedipine and amlodipine, act predominantly on L-type Ca channels, whereas novel CCBs such as efonidipine, benidipine and azelnidipine inhibit both L-type and T-type Ca channels. …
NAID 10029470053

Suppression of Formalin-Induced Nociception by Cilnidipine, a Voltage-Dependent Calcium Channel Blocker

Koganei Hajime,Shoji Masataka,Iwata Seinosuke
Biological and Pharmaceutical Bulletin 32(10), 1695-1700, 2009
… Cilnidipine is a 1,4-dihydropyridine-derived voltage-dependent calcium channel (VDCC) blocker and suppresses N-type VDCC currents in addition to L-type VDCC currents. … An earlier investigation has suggested that intrathecally injected cilnidipine produces antinociception by blocking N-type VDCCs in mice. …
NAID 130000116929

2 海洋共生藻由来の超炭素鎖有機分子の構造と機能(口頭発表の部)

北将樹,大石奈央,小西香織,Han Chunguang,加藤彰,山野喜,Siwu Eric R. O.,北村誠,山田薫,上村大輔
天然有機化合物討論会講演要旨集 (49), 7-12, 2007-08-24
… Symbiodinolide (1), a 62-membered novel polyol macrolide with a molecular weight of 2,859 mu, exhibited a potent voltage-dependent N-type calcium ion channel-opening activity at 7 nM. …
NAID 110006682732

★リンクテーブル★

リンク元	「N型カルシウムチャネル」「N-type calcium channel」「N型電位依存性カルシウムチャネル」
関連記事	「type」「channel」「dependent」「n」「voltage」