WordNet

mark with lines; "sorrow had lined his face"
a length (straight or curved) without breadth or thickness; the trace of a moving point
a single frequency (or very narrow band) of radiation in a spectrum
reinforce with fabric; "lined books are more enduring"
a particular kind of product or merchandise; "a nice line of shoes" (同)product line, line of products, line of merchandise, business line, line of business
the road consisting of railroad track and roadbed (同)railway line, rail line
a commercial organization serving as a common carrier
acting in conformity; "in line with"; "he got out of line"; "toe the line"
something (as a cord or rope) that is long and thin and flexible; "a washing line"
a conceptual separation or distinction; "there is a narrow line between sanity and insanity" (同)dividing_line, demarcation, contrast
a formation of people or things one behind another; "the line stretched clear around the corner"; "you must wait in a long line at the checkout counter"
a formation of people or things one beside another; "the line of soldiers advanced with their bayonets fixed"; "they were arrayed in line of battle"; "the cast stood in line for the curtain call"
a fortified position (especially one marking the most forward position of troops); "they attacked the enemys line"
a mark that is long relative to its width; "He drew a line on the chart"
a spatial location defined by a real or imaginary unidimensional extent
in games or sports; a mark indicating positions or bounds of the playing area
persuasive but insincere talk that is usually intended to deceive or impress; "`let me show you my etchings is a rather worn line"; "he has a smooth line but I didnt fall for it"; "that salesman must have practiced his fast line of talk"
text consisting of a row of words written across a page or computer screen; "the letter consisted of three short lines"; "there are six lines in every stanza"
be in line with; form a line along; "trees line the riverbank" (同)run along
cover the interior of; "line the gloves"; "line a chimney"
fill plentifully; "line ones pockets"
of summer nights in northern latitudes where the sun barely sets; "white nights"
the quality or state of the achromatic color of greatest lightness (bearing the least resemblance to black) (同)whiteness
(board games) the lighter pieces
restricted to whites only; "under segregation there were even white restrooms and white drinking fountains"; "a lily-white movement which would expel Negroes from the organization" (同)lily-white
marked by the presence of snow; "a white Christmas"; "the white hills of a northern winter" (同)snowy
glowing white with heat; "white flames"; "a white-hot center of the fire" (同)white-hot
(of hair) having lost its color; "the white hairs of old age" (同)whitened
(of coffee) having cream or milk added
being of the achromatic color of maximum lightness; having little or no hue owing to reflection of almost all incident light; "as white as fresh snow"; "a brides white dress"
benevolent; without malicious intent; "thats white of you"
free from moral blemish or impurity; unsullied; "in shining white armor"
of or belonging to a racial group having light skin coloration; "voting patterns within the white population"
United States educator who in 1865 (with Ezra Cornell) founded Cornell University and served as its first president (1832-1918) (同)Andrew D. White, Andrew Dickson White
United States writer noted for his humorous essays (1899-1985) (同)E. B. White, Elwyn Brooks White
United States jurist appointed chief justice of the United States Supreme Court in 1910 by President Taft; noted for his work on antitrust legislation (1845-1921) (同)Edward White, Edward D. White, Edward Douglas White Jr.
Australian writer (1912-1990) (同)Patrick White, Patrick Victor Martindale White
United States architect (1853-1906) (同)Stanford White
United States political journalist (1915-1986) (同)T. H. White, Theodore Harold White
a member of the Caucasoid race (同)White person, Caucasian
a tributary of the Mississippi River that flows southeastward through northern Arkansas and southern Missouri (同)White River
a food fish of the Atlantic waters of Europe resembling the cod; sometimes placed in genus Gadus (同)Merlangus merlangus, Gadus merlangus
a small fish of the genus Sillago; excellent food fish
any of several food fishes of North American coastal waters
flesh of a cod-like fish of the Atlantic waters of Europe
flesh of any of a number of slender food fishes especially of Atlantic coasts of North America

PrepTutorEJDIC

『線』,筋,けい / (色・縫い目などの)『線』,しま;(顔・手などの)しわ(wrinkle) / (物・人の)『列』,行列(row) / 『綱』,糸,針金 / 電線,電話線,電信線 / (文章の)『行』;(詩の)『行』 / 《しばしばa~》《話》『短い手紙』(note) / 《複数形で》輪郭,外形(outline) / 境界線(boundary);限界,限度(limit) / (鉄道・バスなどの)路線;航路,空路 / 《複数形で》せりふ / 進路,道順(course);(考えなどの)筋道,方針 / 《しばしばone's~》(活動の)分野,方面;特意 / 家系,血統,血筋 / 在庫商品,仕入れ品 / 導管,パイプライン / 《しばしば複数形で》戦線,防御線 / …‘に'『線を引く』,筋(しま,しわ)をつける / …‘に'『沿って並ぶ;』(…を)…‘に'沿って並べる《+『名』+『with』+『名』》
(材料で)〈着物など〉‘に'裏を付ける《+『名』『with』+『名』》 / (…で)…‘を'満たす,(…を)…‘に'詰め込む《+『名』+『with』+『名』》
〈U〉『白』,白色 / 〈U〉〈C〉白いもの;(特に)『卵の白身』 / 〈U〉『白衣』,白色の服;《しばしば複数形で》白の制服(運動着など) / 〈C〉白人 / 『白い』,白色の,純白の / (恐怖で人・顔・唇などが)『青白い』,血の気のない(pale) / (皮膚の色の)白い,白人の / (髪・ひげなどが)銀色の,改色の / 雪のある,雪の積もった / 《おもに古》潔白の,罪のない / 《英》(コーヒーが)ミルク入りの / …‘を'白くする,漂白する
ニベ(北米産);タラ(欧州産)
(銀の研摩剤に用いる)胡粉,白亜(chalk);漂白剤

UpToDate Contents

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1. 成人における免疫性血小板減少症（ITP）：二次療法 immune thrombocytopenia itp in adults second line and subsequent therapies
2. 成人における24時間携帯血圧および家庭血圧測定ならびに白衣高血圧症 ambulatory and home blood pressure monitoring and white coat hypertension in adults
3. ウォルフ・パーキンソン・ホワイト症候群（WPW症候群）に伴う症候性不整脈の治療 treatment of symptomatic arrhythmias associated with the wolff parkinson white syndrome
4. 外陰部病変：形態に基づく鑑別診断 vulvar lesions differential diagnosis based on morphology
5. 点状角質融解症 pitted keratolysis

English Journal

Anti-caveolin-1 antibodies as anti-prostate cancer therapeutics.

Kuo SR1, Tahir SA, Park S, Thompson TC, Coffield S, Frankel AE, Liu JS.
Hybridoma (2005).Hybridoma (Larchmt).2012 Apr;31(2):77-86. doi: 10.1089/hyb.2011.0100.
Caveolae are critical cell surface structures important in coordinated cell signaling and endocytosis. One of the major proteins of caveolae is caveolin 1 (Cav-1). Cellular levels of Cav-1 are associated with cancer progression. In prostate cancer cells, levels of Cav-1 are positively correlated wit
PMID 22509911

Cytotoxicity of human recombinant arginase I (Co)-PEG5000 in the presence of supplemental L-citrulline is dependent on decreased argininosuccinate synthetase expression in human cells.

Agrawal V1, Woo JH, Mauldin JP, Jo C, Stone EM, Georgiou G, Frankel AE.
Anti-cancer drugs.Anticancer Drugs.2012 Jan;23(1):51-64. doi: 10.1097/CAD.0b013e32834ae42b.
Human recombinant arginase I cobalt [HuArgI (Co)] coupled with polyethylene glycol 5000 [HuArgI (Co)-PEG5000] has shown potent in-vitro depletion of arginine from tissue culture medium. We now show that HuArgI (Co)-PEG5000 is toxic to almost all cancer cell lines and to some normal primary cells exa
PMID 21955999

Targeting methionine auxotrophy in cancer: discovery & exploration.

Agrawal V1, Alpini SE, Stone EM, Frenkel EP, Frankel AE.
Expert opinion on biological therapy.Expert Opin Biol Ther.2012 Jan;12(1):53-61. doi: 10.1517/14712598.2012.636349. Epub 2011 Nov 5.
INTRODUCTION: Amino acid auxotrophy or the metabolic defect which renders cancer incapable of surviving under amino acid depleted conditions is being exploited and explored as a therapeutic against cancer. Early clinical data on asparagine- and arginine-depleting drugs have demonstrated low toxicity
PMID 22171665

★リンクテーブル★

リンク元	「フランケルの白線」
関連記事	「LINE」「line」「white」「lining」「whites」

「フランケルの白線」

　　[★]

英: Frankel white line
同: 壊血病の白線 white line of scurvy
関: 壊血病

「LINE」

　　[★]

日: 長い散在反復配列、長散在型反復配列、長い散在性反復配列、ライン、広範囲散在反復配列
英: long interspersed nuclear element, long interspersed nucleotide element, long interspersed element, long interspersed repetitive elements, LINEs, long interspersed repeat sequences
関: レトロトランスポゾン

quoted from http://en.wikipedia.org/wiki/Long_interspersed_nucleotide_elements#LINEs

Long interspersed nuclear elements[8] are a group of genetic elements that are found in large numbers in eukaryotic genomes. They are transcribed (or are the evolutionary remains of what was once transcribed) to an RNA using an RNA polymerase II promoter that resides inside the LINE. LINEs code for the enzyme reverse transcriptase, and many LINEs also code for an endonuclease (e.g. RNase H). The reverse transcriptase has a higher specificity for the LINE RNA than other RNA, and makes a DNA copy of the RNA that can be integrated into the genome at a new site.

The 5' UTR contains the promoter sequence, while the 3' UTR contains a polyadenylation signal (AATAAA) and a poly-A tail.[10] Because LINEs move by copying themselves (instead of moving, like transposons do), they enlarge the genome. The human genome, for example, contains about 20,000-40,000 LINEs, which is roughly 21% of the genome.