DNA-directed RNA polymerase

DNA依存性RNAポリメラーゼ、DNA指向性RNAポリメラーゼ

関

DNA-dependent RNA polymerase、RNA polymerase、transcriptase

WordNet

1. the enzyme that copies DNA into RNA (同)RNA_polymerase
2. straightforward in means or manner or behavior or language or action; "a direct question"; "a direct response"; "a direct approach"
3. having no intervening persons, agents, conditions; "in direct sunlight"; "in direct contact with the voters"; "direct exposure to the disease"; "a direct link"; "the direct cause of the accident"; "direct vote" (同)unmediated
4. in precisely the same words used by a writer or speaker; "a direct quotation"; "repeated their dialog verbatim" (同)verbatim
5. (of a current) flowing in one direction only; "direct current"
6. be in charge of
7. being an immediate result or consequence; "a direct result of the accident"
8. command with authority; "He directed the children to do their homework"
9. direct in spatial dimensions; proceeding without deviation or interruption; straight and short; "a direct route"; "a direct flight"; "a direct hit"
10. give directions to; point somebody into a certain direction; "I directed them towards the town hall"
11. guide the actors in (plays and films)
12. lacking compromising or mitigating elements; exact; "the direct opposite"
13. moving from west to east on the celestial sphere; or--for planets--around the sun in the same direction as the Earth
14. similar in nature or effect or relation to another quantity; "a term is in direct proportion to another term if it increases (or decreases) as the other increases (or decreases)"
15. the 4th letter of the Roman alphabet (同)d
16. the 18th letter of the Roman alphabet (同)r
17. manageable by a supervising agent; "a directed program of study"
18. (often used in combination) having a specified direction; "a positively directed vector"; "goal-directed"

PrepTutorEJDIC

1. 『まっすぐな』,一直線の(straight),直進する / (列車などが途中駅に寄らずに)直行 / 直系の / 『直接の』,じかの / 『率直な』,単刀直入の / 全くの,絶対の / 原典どおりの / 『まっすぐに』,直行で / 〈事〉‘を'『指揮する』,監督する / 《文》〈人〉‘に'『命令する』,指図する / 〈人〉‘に'(…への)『道を教える』《+『名』〈人〉+『to』+『名』》 / (…に)〈目・注意・努力など〉‘を'『向ける』《+『名』+『to』(『at, toward』)+『名』(do『ing』)》 / 〈音楽・演劇・映画など〉‘を'『指揮する』,演出する,監督する / (…に)〈手紙など〉‘を'あてる《+『名』+『to』+『名』》
2. deuteriumの化学記号
3. resistance / 17歳以下父兄同伴映画の表示 / rook
4. deoxyribonucleic acidディオキシリボ核酸

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/06/01 05:34:01」(JST)

wiki en

[Wiki en表示]

Structure of Taq DNA polymerase

A polymerase is an enzyme (EC 2.7.7.6/7/19/48/49) that synthesizes long chains or polymers of nucleic acids. DNA polymerase and RNA polymerase are used to assemble DNA and RNA molecules, respectively, by copying a DNA or RNA template strand using base-pairing interactions.

It is an accident of history that the enzymes responsible for the generation of other biopolymers are not also referred to as polymerases. For example, the enzymatic complex that assembles amino acids into proteins is termed the ribosome, rather than "protein polymerase".

A polymerase from the thermophilic bacterium, Thermus aquaticus (Taq) (PDB 1BGX, EC 2.7.7.7) is used in the polymerase chain reaction, an important technique of molecular biology.

Other well-known polymerases include:

• Terminal Deoxynucleotidyl Transferase (TDT), which lends diversity to antibody heavy chains

• Reverse Transcriptase, an enzyme used by RNA retroviruses like HIV, which is used to create a complementary strand to the preexisting strand of viral RNA before it can be integrated into the DNA of the host cell. It is also a major target for antiviral drugs.

See also

• DNA polymerase
  • DNA polymerase I
  • DNA polymerase II
  • DNA polymerase III holoenzyme
  • DNA polymerase IV (DinB) – SOS repair polymerase

• RNA polymerase
  • RNA polymerase I
  • RNA polymerase II
  • RNA polymerase III
  • T7 RNA polymerase

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

• 1. 分子遺伝学の原理 principles of molecular genetics
• 2. 遺伝性疾患の基本原則 basic principles of genetic disease
• 3. 抗核抗体の測定および臨床的意義 measurement and clinical significance of antinuclear antibodies
• 4. 全身疾患と関連した遺伝性ニューロパチー hereditary neuropathies associated with generalized disorders
• 5. 成人における全身性硬化症（強皮症）の診断および鑑別診断 diagnosis and differential diagnosis of systemic sclerosis scleroderma in adults

English Journal

• RNA-Directed DNA Methylation: The Evolution of a Complex Epigenetic Pathway in Flowering Plants.

• Matzke MA1, Kanno T, Matzke AJ.
• Annual review of plant biology.Annu Rev Plant Biol.2015 Apr 29;66:243-267. Epub 2014 Dec 10.
• RNA-directed DNA methylation (RdDM) is an epigenetic process in plants that involves both short and long noncoding RNAs. The generation of these RNAs and the induction of RdDM rely on complex transcriptional machineries comprising two plant-specific, RNA polymerase II (Pol II)-related RNA polymerase
• PMID 25494460

• Step-wise and lineage-specific diversification of plant RNA polymerase genes and origin of the largest plant-specific subunits.

• Wang Y1, Ma H.
• The New phytologist.New Phytol.2015 Apr 29. doi: 10.1111/nph.13432. [Epub ahead of print]
• Proteins often function as complexes, yet little is known about the evolution of dissimilar subunits of complexes. DNA-directed RNA polymerases (RNAPs) are multisubunit complexes, with distinct eukaryotic types for different classes of transcripts. In addition to Pol I-III, common in eukaryotes, pla
• PMID 25921392

• Complex Formation of RNA Silencing Proteins in the Perinuclear Region of Neurospora crassa.

• Decker LM1, Boone EC1, Xiao H1, Shanker BS1, Boone SF1, Kingston SL2, Lee SA1, Hammond TM3, Shiu PK4.
• Genetics.Genetics.2015 Apr;199(4):1017-21. doi: 10.1534/genetics.115.174623. Epub 2015 Feb 2.
• In Neurospora, genes not paired during meiosis are targeted by meiotic silencing by unpaired DNA (MSUD). Here, our bimolecular fluorescence complementation (BiFC) study suggests that RNA-directed RNA polymerase, Dicer, Argonaute, and others form a silencing complex in the perinuclear region, with in
• PMID 25644701

Japanese Journal

• Preparation of S-Protected Cysteine-Containing Peptide Thioester and Its Use for the Synthesis of the Barnase-Like Domain in DNA-Directed RNA Polymerase II of Saccharomyces cerevisiae

• HOJO Hironobu,YOSHIMURA Shoko,GO Mitiko,AIMOTO Saburo
• Bulletin of the Chemical Society of Japan 68(1), 330-336, 1995-01-15
• NAID 10008885262

Related Links

• DNA-directed RNA polymerase - definition of DNA-directed ...

Definition of DNA-directed RNA polymerase in the Medical Dictionary. DNA-directed RNA polymerase explanation. Information about DNA-directed RNA polymerase in Free online English dictionary. What is DNA-directed RNA ...

• ViralZone: DNA-directed RNA polymerase

A knowledge resource to understand virus diversity ... RP07_VACCC DNA-directed RNA polymerase 7 kDa subunit (EC 2.7.7.6) RP132_VACCC DNA-directed RNA polymerase 133 kDa polypeptide (EC 2.7.7.6) RP147_VACCC DNA ...

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★リンクテーブル★

リンク元	「DNA依存性RNAポリメラーゼ」「DNA-dependent RNA polymerase」「transcriptase」「DNA指向性RNAポリメラーゼ」
関連記事	「direct」「D」「R」「RNA」「DNA」

「DNA依存性RNAポリメラーゼ」

　　[★]

英

DNA-dependent RNA polymerase、DNA-directed RNA polymerase

関

RNAポリメラーゼ、転写酵素、DNA指向性RNAポリメラーゼ

「DNA-dependent RNA polymerase」

　　[★]

DNA依存性RNAポリメラーゼ

関

DNA-directed RNA polymerase、RNA polymerase、transcriptase

「transcriptase」

　　[★]

• 転写酵素

関

DNA-dependent RNA polymerase、DNA-directed RNA polymerase、RNA polymerase

　

「DNA指向性RNAポリメラーゼ」

　　[★]

英

DNA-directed RNA polymerase

関

DNA依存性RNAポリメラーゼ

「direct」

　　[★]

• adj.

• 直接の、直接的な、直接型の、ダイレクトな

• v.

• 指示する、向ける、指揮する、方向づける、指導する、配向する

関

coach、conduct、dictate、direction、directly、guidance、guide、immediate、indicate、indication、instruct、instruction、orient、orientation、point、straightforward、tutorial

　 　 　 　 　 　 　 　 　 　 　 　 　 　

「D」

　　[★]

• アスパラギン酸
• ジヒドロウリジン
• 遠位の distal,
• うつ病 depression
• 下行結腸 descending colon(大腸内視鏡検査の結果を記載するときに用いる)

　 　

「R」

　　[★]

• レントゲン roentgen
• アルギニン
• respiratory rate
• respiratory quotient
• プリン
• アルキル基 alkyl group
• 化合物の側鎖

　 　

「RNA」

　　[★]

同

リボ核酸 ribonucleic acid RNA

関

DNA

• D-リボースを糖成分とする核酸

　

「DNA」

　　[★]

英

deoxyribonucleic acid

同

デオキシリボ核酸

関

リボ核酸 RNA