カルモジュリンキナーゼ、カルモジュリン依存性キナーゼ、CaMキナーゼ
- 関
- calmodulin kinase、calmodulin-dependent protein kinase、CaMK
WordNet
- the 3rd letter of the Roman alphabet (同)c
- (music) the keynote of the scale of C major
- a general-purpose programing language closely associated with the UNIX operating system
- a rotating disk shaped to convert circular into linear motion
- an enzyme that catalyzes the conversion of a proenzyme to an active enzyme
PrepTutorEJDIC
- carbonの化学記号
- カム,歪(わい)輪(機械の回転運動を水平・上下などの運動に変える)
- Calciumの化学記号
UpToDate Contents
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English Journal
- Disturbance of Intracellular Calcium Homeostasis and CaMKII/CREB Signaling is Associated with Learning and Memory Impairments Induced by Chronic Aluminum Exposure.
- Wang B1, Zhao J, Yu M, Meng X, Cui X, Zhao Y, Zhu Y, Xing W, Guan Y.
- Neurotoxicity research.Neurotox Res.2014 Jul;26(1):52-63. doi: 10.1007/s12640-013-9451-y. Epub 2013 Dec 24.
- Aluminum-induced neuronal injury has been implicated in various neurodegenerative disorders. However, the underlying mechanism involved in this pathogenesis still remains unknown. Our present findings demonstrated that chronic aluminum exposure resulted in spatial learning impairment and significant
- PMID 24366850
- The phosphorylation status of Ascl1 is a key determinant of neuronal differentiation and maturation in vivo and in vitro.
- Ali FR1, Cheng K2, Kirwan P3, Metcalfe S4, Livesey FJ3, Barker RA4, Philpott A5.
- Development (Cambridge, England).Development.2014 Jun;141(11):2216-24. doi: 10.1242/dev.106377. Epub 2014 May 12.
- Generation of neurons from patient fibroblasts using a combination of developmentally defined transcription factors has great potential in disease modelling, as well as ultimately for use in regeneration and repair. However, generation of physiologically mature neurons in vitro remains problematic.
- PMID 24821983
- The amino terminus of high-voltage-activated calcium channels: CaM you or can't you?
- Simms BA, Souza IA, Rehak R, Zamponi GW.
- Channels (Austin, Tex.).Channels (Austin).2014 May 29;8(4). [Epub ahead of print]
- Voltage-gated calcium channels (VGCCs), calmodulin (CaM), and calmodulin kinase II (CaMKII) are essential for various nervous system functions. CaM and CaMKII differentially regulate calcium dependent facilitation (CDF) and calcium dependent inactivation (CDI) of the Cav1 and Cav2 families of VGCCs.
- PMID 24875328
Japanese Journal
- Inhibitory Effect of Chlorpromazine on RANKL-Induced Osteoclastogenesis in Mouse Bone Marrow Cells
- Kawamura Hiroharu,Arai Michitsugu,Togari Akifumi
- Journal of pharmacological sciences 117(1), 54-62, 2011-09-20
- … Chlorpromazine (CPZ), the first widely used phenothiazine tranquilizer, is shown to inhibit the action of intracellular calmodulin (CaM) and bone resorption in vivo and in vitro. … and characteristic markers of osteoclasts such as TRAP, cathepsin K, carbonic anhydrase II, and calcitonin receptor in BMCs were up-regulated by s-RANKL and decreased by the addition of CPZ (5 <I>μ</I>M) or the selective CaM antagonist W7, but not the inactive analog W5. …
- NAID 10029895980
- Ca(2+)-dependent binding of calcium-binding protein 1 to presynaptic group III metabotropic glutamate receptors and blockage by phosphorylation of the receptors.
- Nakajima Yoshiaki
- Biochemical and biophysical research communications 412(4), 602-605, 2011-09-09
- … Among these, calmodulin (CaM) and the related EF-hand Ca(2+)-binding proteins are of particular importance as sensors of presynaptic Ca(2+), and a multiple of them are indeed utilized in the signaling of Ca(2+) channels. … However, despite its conserved structure, CaM is the only known EF-hand Ca(2+)-binding protein for signaling by presynaptic group III mGluRs. …
- NAID 80021990000
- Mechanisms Underlying the Anti-inflammatory Effects of the Ca^<2+>/Calmodulin Antagonist CV-159 in Cultured Vascular Smooth Muscle Cells
- Usui Tatsuya,Yamawaki Hideyuki,Kamibayashi Masato [他],OKADA Muneyoshi,HARA Yukio
- Journal of pharmacological sciences 113(3), 214-223, 2010-07-20
- … antagonist with an anti-calmodulin (CaM) action. … A CaM inhibitor, W-7, and a calcium/CaM-dependent protein kinase type II inhibitor, KN93, inhibited TNF-induced VCAM-1. … CV-159 prevents NF-<I>κ</I>B phosphorylation by inhibiting ROS, while it prevents Akt phosphorylation by inhibiting both ROS and CaM. …
- NAID 10029889201
Related Links
- CaMキナーゼに特異的なネガティブ制御因子 <研究内容> <研究室関連ニュース> <リンク> | HOME | CaMキナーゼホスファターゼの構造と機能 | 更新日 2015-06-04 | 作成日 2008-01-20 CaMキナーゼホスファターゼの構造と機能 ...
- 通常の神経活動状態では、細胞内のCa 2+ /カルモジュリン(Ca 2+ /CaM)濃度、CaMKII自身の活性、脱リン酸化酵素であるフォスファターゼ(phosphatases)活性のバランスによって、CaMKIIの活性状態は平衡状態に保たれています ) ...
Related Pictures
★リンクテーブル★
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- 英
- calmodulin-dependent protein kinase、CaM kinase
- 関
- カルモジュリンキナーゼ、カルモジュリン依存性プロテインキナーゼ、CaMキナーゼ、カルシウム・カルモジュリン依存性プロテインキナーゼ
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カルモジュリン依存性プロテインキナーゼ、カルモジュリン依存性キナーゼ
- 関
- calcium-calmodulin-dependent protein kinase、calmodulin kinase、CaM kinase、CaMK
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カルモジュリンキナーゼ、カルモジュリン依存性プロテインキナーゼ
- 関
- calmodulin kinase、calmodulin-dependent protein kinase、CaM kinase
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カルモジュリンキナーゼ
- 関
- calcium-calmodulin-dependent protein kinase、calmodulin-dependent protein kinase、CaM kinase、CaMK
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- 関
- calcium-calmodulin-dependent protein kinase type 2、calmodulin kinase II、calmodulin-dependent protein kinase II、CaM KII、CaMKII
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- 関
- calcium-calmodulin-dependent protein kinase type 1、calmodulin kinase I、calmodulin-dependent protein kinase I、CaM KI、CaMKI
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カルモジュリンキナーゼ
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キナーゼ カイネース リン酸化酵素 phosphoenzyme phosphotransferase
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カルシウム calcium