WordNet

bring into conformity with rules or principles or usage; impose regulations; "We cannot regulate the way people dress"; "This town likes to regulate" (同)regularize, regularise, order, govern
fix or adjust the time, amount, degree, or rate of; "regulate the temperature"; "modulate the pitch" (同)modulate
the 1st letter of the Roman alphabet (同)a
the blood group whose red cells carry the A antigen (同)type_A, group A
controlled or governed according to rule or principle or law; "well regulated industries"; "houses with regulated temperature"

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1. 虚血プレコンディショニングの定義および病因 definition and pathogenesis of ischemic preconditioning
2. 黄疸または無症候性高ビリルビン血症の分類および原因 classification and causes of jaundice or asymptomatic hyperbilirubinemia
3. サーファクタント機能障害の遺伝性疾患 genetic disorders of surfactant dysfunction
4. 癌における悪液質の病因、臨床的特徴および評価 pathogenesis clinical features and assessment of cancer cachexia
5. 小児における重症喘息の急性増悪：気管内挿管および人工呼吸器の使用 acute severe asthma exacerbations in children endotracheal intubation and mechanical ventilation

Activation of Hsp90 Enzymatic Activity and Conformational Dynamics through Rationally Designed Allosteric Ligands.

Sattin S1, Tao J2, Vettoretti G3, Moroni E3, Pennati M4, Lopergolo A4, Morelli L1, Bugatti A5, Zuehlke A6, Moses M6, Prince T6, Kijima T6, Beebe K6, Rusnati M5, Neckers L6, Zaffaroni N4, Agard DA2, Bernardi A1, Colombo G7.
Chemistry (Weinheim an der Bergstrasse, Germany).Chemistry.2015 Sep 21;21(39):13598-608. doi: 10.1002/chem.201502211. Epub 2015 Aug 18.
Hsp90 is a molecular chaperone of pivotal importance for multiple cell pathways. ATP-regulated internal dynamics are critical for its function and current pharmacological approaches block the chaperone with ATP-competitive inhibitors. Herein, a general approach to perturb Hsp90 through design of new
PMID 26286886

Kanno T1, Berta DG1, Sjögren C2.
Cell reports.Cell Rep.2015 Sep 1;12(9):1471-82. doi: 10.1016/j.celrep.2015.07.048. Epub 2015 Aug 20.
The structural maintenance of chromosome (SMC) protein complexes cohesin and condensin and the Smc5/6 complex (Smc5/6) are crucial for chromosome dynamics and stability. All contain essential ATPase domains, and cohesin and condensin interact with chromosomes through topological entrapment of DNA.
PMID 26299966

Chaperonin-Assisted Protein Folding: Relative Population of Asymmetric and Symmetric GroEL:GroES Complexes.

Haldar S1, Gupta AJ1, Yan X1, Miličić G1, Hartl FU2, Hayer-Hartl M3.
Journal of molecular biology.J Mol Biol.2015 Jun 19;427(12):2244-55. doi: 10.1016/j.jmb.2015.04.009. Epub 2015 Apr 23.
The chaperonin GroEL, a cylindrical complex consisting of two stacked heptameric rings, and its lid-like cofactor GroES form a nano-cage in which a single polypeptide chain is transiently enclosed and allowed to fold unimpaired by aggregation. GroEL and GroES undergo an ATP-regulated interaction cyc
PMID 25912285