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1. 高抱合型ビリルビン血症関連の遺伝性疾患inherited disorders associated with conjugated hyperbilirubinemia [show details]
… the selective serotonin reuptake inhibitor sertraline, which increases neurotransmitter concentrations within the central nervous system ,… disrupts this re-uptake process, resulting in Rotor syndrome . Notably, mutations of OATP1B1 or OATP1B3 alone do not cause jaundice. However, these transporters mediate the uptake of many other…
2. セロトニン - ノルエピネフリン再取り込み阻害剤（SNRIs）：薬理学、投与、および副作用serotonin norepinephrine reuptake inhibitors snris pharmacology administration and side effects [show details]
… This inhibits reuptake of these neurotransmitters and leads to increased stimulation of postsynaptic receptors. The pharmacokinetic parameters of SNRIs vary Duloxetine moderately inhibits the hepatic… All drugs that inhibit serotonin uptake can cause sexual dysfunction.…
3. 成人における緊張型頭痛：予防的治療tension type headache in adults preventive treatment [show details]
… the available evidence suggests that the selective serotonin uptake inhibitors are not effective for TTH prophylaxis.… Tricyclic antidepressants are reuptake inhibitors of serotonin and noradrenaline, and these neurotransmitter interactions are the presumed mechanism…
4. 長期にわたる術後イレウスに対する予防策measures to prevent prolonged postoperative ileus [show details]
…Selective COX-2 inhibitors include celecoxib and etoricoxib (the latter is not available in the United States). Other agents work by inhibiting or augmenting the activity of neurotransmitters that carry …
5. 急性周術期疼痛のマネージメントmanagement of acute perioperative pain [show details]
… the activity of neurotransmitters by inhibiting or augmenting their activity (eg, ketamine, clonidine, acetaminophen, gabapentin, pregabalin) Neurotransmitters are responsible… spinal cord by suppressing excitatory neuropeptide release from nerve fibers (type C). The degree of uptake from the CSF by the dorsal horn is determined primarily by the physicochemical properties of the …