WordNet

limit, block, or decrease the action or function of; "inhibit the action of the enzyme"; "inhibit the rate of a chemical reaction"
control and refrain from showing; of emotions, desires, impulses, or behavior (同)bottle up, suppress
limit the range or extent of; "Contact between the young was inhibited by strict social customs"
a process of taking up or using up or consuming; "they developed paper napkins with a greater uptake of liquids"
a substance that retards or stops an activity
a neurochemical that transmits nerve impulses across a synapse

PrepTutorEJDIC

《所有・所属》…『の』,…のものである,…に属する・《材料・要素》…『でできた』,から成る・《部分》…『の』[『中の』] ・《数量・単位・種類を表す名詞に付いて》…の・《原因・動機》…『で』,のために(because of) ・《主格関係》…『の』,による,によって・《目的格関係》…『を』,の・《同格関係》…『という』・《関係・関連》…『についての』[『の』],の点で・《抽象名詞などと共に》…の[性質をもつ] ・《『It is』+『形』+『of』+『名』+『to』 doの形で,ofの後の名詞を意味上の主語として》・《分離》…『から』・《起原・出所》…『から』[『の』](out of) ・《『名』+『of』+『a』(『an』)+『名』の形で》…のような・《『名』+『of』+『mine』(『yours, his』など独立所有格)の形で》…の…・《時》(1)《副詞句を作って》…に《形容詞句を作って》…の・《時刻》《米》…前(to,《米》before)
〈感情・欲望・行動・作用など〉‘を'抑制する / (…しないように)〈人〉‘を'抑制する,妨げる《+『名』+『from』+『名』(do『ing』)》
〈U〉《the up. take》《話》理解,予解 / 〈C〉(鉱山などで空気や煙の)吸い上げパイプ
抑制する人(物) / 化学反応抑制剤

UpToDate Contents

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1. 急性周術期疼痛のマネージメント management of acute perioperative pain
2. セロトニン - ノルエピネフリン再取り込み阻害剤（SNRIs）：薬理学、投与、および副作用 serotonin norepinephrine reuptake inhibitors snris pharmacology administration and side effects
3. 糖尿病性神経障害の治療 treatment of diabetic neuropathy
4. 成人における緊張型頭痛：予防的治療 tension type headache in adults preventive treatment
5. 慢性疼痛の治療の概要 overview of the treatment of chronic pain

English Journal

Potentiating SLC transporter activity: Emerging drug discovery opportunities.

Rives ML1, Javitch JA2, Wickenden AD3.
Biochemical pharmacology.Biochem Pharmacol.2017 Jul 1;135:1-11. doi: 10.1016/j.bcp.2017.02.010. Epub 2017 Feb 16.
PMID 28214518

Relief of Pain-Depressed Behavior in Rats by Activation of D1-Like Dopamine Receptors.

Lazenka MF1, Freitas KC1, Henck S1, Negus SS2.
The Journal of pharmacology and experimental therapeutics.J Pharmacol Exp Ther.2017 Jul;362(1):14-23. doi: 10.1124/jpet.117.240796. Epub 2017 Apr 14.
PMID 28411257

Deconstructed Analogues of Bupropion Reveal Structural Requirements for Transporter Inhibition versus Substrate-Induced Neurotransmitter Release.

Shalabi AR1, Walther D2, Baumann MH2, Glennon RA1.
ACS chemical neuroscience.ACS Chem Neurosci.2017 Jun 21;8(6):1397-1403. doi: 10.1021/acschemneuro.7b00055. Epub 2017 Feb 27.
PMID 28220701

Japanese Journal

A Highly Selective Inhibitor of Glycine Transporter-1 Elevates the Threshold for Maximal Electroshock-Induced Tonic Seizure in Mice

Biological and Pharmaceutical Bulletin 39(2), 174-180, 2016
NAID 130005122358

A highly selective inhibitor of glycine transporter-1 elevates the threshold for maximal electroshock-induced tonic seizure in mice

Biological and Pharmaceutical Bulletin advpub(0), 2016
NAID 130005112654

骨組織における機能的グルタミン酸シグナリング

YAKUGAKU ZASSHI 130(9), 1175-1179, 2010
NAID 130000342377

Related Links

Neurotransmitter Uptake Inhibitors | DrugBank Online

Drugs that inhibit the transport of neurotransmitters into axon terminals or into storage vesicles within terminals. For many transmitters, uptake determines the time course of transmitter action so inhibiting uptake prolongs the activity of the transmitter. Blocking uptake may also deplete available transmitter stores.

Neurotransmitter_uptake_inhibitor - chemeurope.com

Neurotransmitter uptake inhibitor A neurotransmitter uptake inhibitor is a drug which inhibits the reuptake of the neurotransmitter, thus extending the my.chemeurope.com With an accout for my.chemeurope.com you can ...

Dopamine Uptake Inhibitor - an overview | ScienceDirect Topics

Thus, a large investment in discovering and developing novel DA uptake inhibitors, both selective for DAT and also nonselective monoamine transport inhibitors has transpired over the past 15 years, resulting in an arsenal of compounds, based on cocaine, GBR 12909, benztropine, mazindol, methylphenidate, and rimcazole. 53,77,78 Many of these compounds demonstrate a cocaine-like behavioral profile in animal models, and could be potential ‘substitute’ therapy candidates.