ビタミンD依存性カルシウム結合タンパク質
WordNet
- executed with proper legal authority; "a binding contract"
- the protective covering on the front, back, and spine of a book; "the book had a leather binding" (同)book binding, cover, back
- strip sewn over or along an edge for reinforcement or decoration
- the capacity to attract and hold something
- relying on or requiring a person or thing for support, supply, or what is needed; "dependent children"; "dependent on moisture"
- addicted to a drug (同)dependant, drug-addicted, hooked, strung-out
- contingent on something else (同)dependant, qualified
- (of a clause) unable to stand alone syntactically as a complete sentence; "a subordinate (or dependent) clause functions as a noun or adjective or adverb within a sentence" (同)subordinate
- any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
- the 4th letter of the Roman alphabet (同)d
- a white metallic element that burns with a brilliant light; the fifth most abundant element in the earths crust; an important component of most plants and animals (同)Ca, atomic number 20
PrepTutorEJDIC
- 義務的な,拘束力ある / 〈U〉しばること;〈C〉しばる物 / 〈C〉製本,装丁 / 〈U〉縁(‘ふち')取り材料
- 『頼っている』,依存している,従属している / 扶養される人(家族)
- 蛋白(たんばく)質
- deuteriumの化学記号
- 『カルシウム』(金属元素;化学記号は『Ca』)
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2012/12/25 16:08:42」(JST)
[Wiki en表示]
Vitamin D-dependent calcium binding proteins were discovered in the cytosolic fractions of chicken intestine, and later in mammalian intestine and kidney, by workers including Robert Wasserman of Cornell University.
They bound calcium in the micromolar range and were greatly reduced in vitamin D-deficient animals. Expression could be induced by treating these animals with vitamin D metabolites such as calcitriol.
They were found to exist in two distinct sizes with a molecular weight of approximately 9 kDa and 28 kDa. They were renamed calbindin; calbindin-D9k (S100G) is found in mammalian intestine and calbindin-D28k in avian intestine and in kidney.
See also
External links
- Vitamin+D-Dependent+Calcium-Binding+Protein at the US National Library of Medicine Medical Subject Headings (MeSH)
- Calcium Vitamins
Cell signaling: calcium signaling / calcium metabolism
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Cell membrane |
Ion pumps
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- SERCA
- Sodium-calcium exchanger
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Cell membrane calcium channels
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- VDCC
- TRP
- NMDA receptor
- AMPA receptor
- 5-HT3 receptor
- P2X purinoreceptor
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Adhesion molecules
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Other
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Intracellular signaling
& calc. regulation |
Second messengers
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Store gates
(ligand gated calcium channel)
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Molecular switches, and kinases
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- Troponin C
- Calmodulin
- CaM kinases
- PKC
- NCS
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Chelators and calcium sensors
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- Calbindin
- S100
- pervalbumin
- Calretinin
- Calsequestrin
- Sarcalumenin
- Phospholamban
- Synaptotagmins
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Proteases
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Cytoskeleton remodeling proteins
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Chaperones
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Other
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Calcium-binding
protein domains |
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Extracellular ligands |
- Parathyroid hormone
- Calcitonin
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Calcium-binding proteins |
Intracellular calcium-sensing proteins
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- Calmodulin
- Calnexin
- Calreticulin
- Gelsolin
- neuronal
- Hippocalcin
- Neurocalcin
- Recoverin
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Membrane protein
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- Vitamin D-dependent calcium-binding protein/Calbindin
- Calexcitin
- Calsequestrin
- Osteocalcin
- Osteonectin
- S-100
- Synaptotagmin
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Cytoskeleton
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Extracellular matrix
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B trdu: iter (nrpl/grfl/cytl/horl), csrc (lgic, enzr, gprc, igsr, intg, nrpr/grfr/cytr), itra (adap, gbpr, mapk), calc, lipd; path (hedp, wntp, tgfp+mapp, notp, jakp, fsap, hipp, tlrp)
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UpToDate Contents
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English Journal
- Calretinin is essential for mesothelioma cell growth/survival in vitro: a potential new target for malignant mesothelioma therapy?
- Blum W1, Schwaller B.
- International journal of cancer. Journal international du cancer.Int J Cancer.2013 Nov;133(9):2077-88. doi: 10.1002/ijc.28218. Epub 2013 Jul 9.
- Malignant mesothelioma (MM) are highly aggressive asbestos-related neoplasms, which show strong chemotherapy resistance, and there is no effective cure for MM so far. Calretinin (CR) is widely used as a diagnostic marker for epithelioid and mixed (biphasic) mesothelioma; however, little is known abo
- PMID 23595591
- Therapeutic strategies for well-differentiated papillary mesothelioma of the peritoneum.
- Lee YK1, Jun HJ, Nahm JH, Lim TS, Park JS, Ahn JB, Rha SY, Chung HC, Oh HE, Song JS, Yang WI, Kim HS.
- Japanese journal of clinical oncology.Jpn J Clin Oncol.2013 Oct;43(10):996-1003. doi: 10.1093/jjco/hyt117. Epub 2013 Aug 20.
- OBJECTIVE: Well-differentiated papillary mesothelioma is an uncommon subtype of mesothelioma with a frequently indolent course, although it occasionally manifests in a more aggressive form. To establish a treatment strategy for this rare disease, we report the clinical characteristics and outcomes o
- PMID 23964112
- An in-cell NMR study of monitoring stress-induced increase of cytosolic Ca2+ concentration in HeLa cells.
- Hembram DS1, Haremaki T, Hamatsu J, Inoue J, Kamoshida H, Ikeya T, Mishima M, Mikawa T, Hayashi N, Shirakawa M, Ito Y.
- Biochemical and biophysical research communications.Biochem Biophys Res Commun.2013 Sep 6;438(4):653-9. doi: 10.1016/j.bbrc.2013.07.127. Epub 2013 Aug 8.
- Recent developments in in-cell NMR techniques have allowed us to study proteins in detail inside living eukaryotic cells. The lifetime of in-cell NMR samples is however much shorter than that in culture media, presumably because of various stresses as well as the nutrient depletion in the anaerobic
- PMID 23933251
Japanese Journal
- Effects of Aminoglutethimide on Levels of Messenger Ribonucleic Acid of CaBP-D28K and of Vitamin D3 Receptor in the Shell Gland of Laying Hen.
- Extracorporeal Shockwave Lithotripsyによる腎組織損傷のマーカーとしての28-kDa Calbindin-Dの有用性
- Somatostatin-like immunoreactivity in rat main olfactory bulb: extent of coexistence with neuropeptide Y-, tyrosine hydroxylase- and vitamin D-dependent calcium binding protein-like immunoreactivities.
Related Links
- Placental Synthesis of Calcium- binding Protein 4653 by day 17. These changes may indicate gestational-dependent changes in synthetic rates for total soluble ...
- 1. Am J Physiol. 1990 Aug;259(2 Pt 2):F195-209. Physiology and biochemistry of vitamin D-dependent calcium binding proteins. Gross M, Kumar R.
★リンクテーブル★
[★]
- 英
- vitamin D-dependent calcium-binding protein
[★]
- 関
- affinity、associate、bind、bond、bonding、combine、conjoin、conjugate、conjugation、conjunction、connect、connection、connective、connectivity、couple、dock、engage、engagement、join、ligate、linkage、symphysial、symphysic、union
[★]
[★]
- 関
- depend、dependence、dependency、dependently
[★]
- 関
- BP、carrier protein、transport protein
[★]