I型コラーゲン
- 関
- collagen I、collagen type I、type 1 collagen
WordNet
- write by means of a keyboard with types; "type the acceptance letter, please" (同)typewrite
- a small metal block bearing a raised character on one end; produces a printed character when inked and pressed on paper; "he dropped a case of type, so they made him pick them up"
- (biology) the taxonomic group whose characteristics are used to define the next higher taxon
- a subdivision of a particular kind of thing; "what type of sculpture do you prefer?"
- all of the tokens of the same symbol; "the word `element contains five different types of character"
- printed characters; "small type is hard to read"
- identify as belonging to a certain type; "Such people can practically be typed" (同)typecast
- a paste-up made by sticking together pieces of paper or photographs to form an artistic image; "he used his computer to make a collage of pictures superimposed on a map" (同)montage
- any collection of diverse things; "a collage of memories"
- the 9th letter of the Roman alphabet (同)i
- a fibrous scleroprotein in bone and cartilage and tendon and other connective tissue; yields gelatin on boiling
- writing done with a typewriter (同)typewriting
PrepTutorEJDIC
- 〈C〉(…の)『型』,タイプ,類型,種類(kind)《+of+名》 / 〈C〉(その種類の特質を最もよく表している)『典型』,手本,模範《+of+名》 / 〈U〉《集合的に》活字;〈C〉(1個の)活字 / 〈U〉(印刷された)字体,活字 / 〈C〉(貨幣・メダルなどの)模様,図柄 / 〈C〉血液型(blood group) / …‘を'タイプに打つ / (…として)…‘を'分類する《+名+as+名(doing)》 / …‘の'型を決める / タイプライターを打つ
- コラージュ / 〈C〉画面に絵具以外のいろいろな素材を貼り付けて耕成した絵 / 〈U〉1の絵画技法
- 『私は』私が
- iodineの化学記号
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/08/14 23:10:55」(JST)
[Wiki en表示]
collagen, type I, alpha 1 |
Identifiers |
Symbol |
COL1A1 |
Entrez |
1277 |
HUGO |
2197 |
OMIM |
120150 |
RefSeq |
NM_000088 |
UniProt |
P02452 |
Other data |
Locus |
Chr. 17 q21.3-q22 |
collagen, type I, alpha 2 |
Identifiers |
Symbol |
COL1A2 |
Alt. symbols |
OI4 |
Entrez |
1278 |
HUGO |
2198 |
OMIM |
120160 |
RefSeq |
NM_000089 |
UniProt |
P08123 |
Other data |
Locus |
Chr. 7 q21.3-22.1 |
Type I collagen is the most abundant collagen of the human body which forms large, eosinophilic fibers known as collagen fibers. It is present in scar tissue, the end product when tissue heals by repair, as well as tendons, ligaments, the endomysium of myofibrils, the organic part of bone, the dermis, the dentin and organ capsules.
See also
- Collagen
- Type II collagen
- Collagen, type III, alpha 1
- COL1A1
- COL1A2
External links
- Collagen type I at the US National Library of Medicine Medical Subject Headings (MeSH)
References
Junqueira's Basic Histology, P106
Protein: scleroproteins
|
|
Extracellular matrix |
Collagen |
Fibril forming |
- type I
- type II (COL2A1)
- type III
- type V
- COL24A1
- COL26A1
|
|
Other |
- FACIT: type IX
- type XII (COL12A1)
- COL14A1
- COL16A1
- COL19A1
- COL20A1
- COL21A1
- COL22A1
- basement membrane: type IV
- COL4A1
- COL4A2
- COL4A3
- COL4A4
- COL4A5
- COL4A6
- multiplexin: COL15A1
- type XVIII
- transmembrane: COL13A1
- COL17A1
- COL23A1
- COL25A1
- other: type VI
- COL6A1
- COL6A2
- COL6A3
- COL6A5
- type VII (COL7A1)
- type VIII
- type X (COL10A1)
- type XI
- COL27A1
- COL28A1
|
|
Enzymes |
- Prolyl hydroxylase/Lysyl hydroxylase
- Cartilage associated protein/Leprecan
- ADAMTS2
- Procollagen peptidase
- Lysyl oxidase
|
|
|
Laminin |
- alpha
- LAMA1
- LAMA2
- LAMA3
- LAMA4
- LAMA5
- beta
- gamma
|
|
Other |
- ALCAM
- Elastin
- Vitronectin
- FRAS1
- FREM2
- Decorin
- FAM20C
- ECM1
- Matrix gla protein
- Tectorin
|
|
|
Other |
- Keratin/Cytokeratin
- Gelatin
- Reticulin
- Cartilage oligomeric matrix protein
|
|
- See also
- diseases B proteins: BY STRUCTURE: membrane, globular (en, ca, an), fibrous
|
|
UpToDate Contents
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English Journal
- Astragaloside IV controls collagen reduction in photoaging skin by improving transforming growth factor-β/Smad signaling suppression and inhibiting matrix metalloproteinase-1.
- Chen B1, Li R1, Yan N1, Chen G1, Qian W1, Jiang HL1, Ji C2, Bi ZG3.
- Molecular medicine reports.Mol Med Rep.2015 May;11(5):3344-8. doi: 10.3892/mmr.2015.3212. Epub 2015 Jan 16.
- Exposure to ultraviolet (UV) light reduces levels of type I collagen in the dermis and results in human skin damage and premature skin aging (photoaging). This leads to a wrinkled appearance through the inhibition of transforming growth factor‑β (TGF‑β)/Smad signaling. UV irradiation increases
- PMID 25591734
- Unique micro- and nano-scale mineralization pattern of human osteogenesis imperfecta type VI bone.
- Fratzl-Zelman N1, Schmidt I2, Roschger P3, Roschger A4, Glorieux FH5, Klaushofer K3, Wagermaier W2, Rauch F5, Fratzl P2.
- Bone.Bone.2015 Apr;73:233-41. doi: 10.1016/j.bone.2014.12.023. Epub 2014 Dec 29.
- Osteogenesis imperfecta (OI) is a heterogeneous group of inheritable connective tissue disorders characterized by mutation in genes involved in collagen synthesis and leading to increased bone fragility, low bone mass, impaired bone material properties and abnormally high bone matrix mineralization.
- PMID 25554599
- Simultaneous delivery of BMP-2 factor and anti-osteoporotic drugs using hyaluronan-assembled nanocomposite for synergistic regulation on the behaviors of osteoblasts and osteoclasts in vitro.
- Zhang Y1, Hu Y, Luo Z, Shen X, Mu C, Cai K.
- Journal of biomaterials science. Polymer edition.J Biomater Sci Polym Ed.2015 Apr;26(5):290-310. doi: 10.1080/09205063.2014.998588. Epub 2015 Jan 13.
- To treat the osteoporosis and regulate the biological behaviors of both osteoblasts and osteoclasts, we prepared a natural polysaccharide-derived nanocomposite, containing alendronate-grafted hyaluronate (HA-Aln) and bone morphogenetic protein 2 (BMP-2) and investigated its synergistic regulation on
- PMID 25585099
Japanese Journal
- 出雲 令子/豊口 光子/島川 眞知子/篠崎 和美/高村 悦子/堀 貞夫
- 東京女子医科大学雑誌 82(E1), E173-E177, 2012-01-31
- 【目的】東京女子医大眼科における強膜炎の臨床像および全身疾患について調査した。,【方法】2009年4月から2010年3月までに当院眼科を受診した強膜炎42例を対象とし、Watson分類に従い強膜炎のタイプを分類し、臨床像、全身疾患、治療について検討した。,【結果】発症時の平均年齢は52.9±15.8歳、男性13例、女性29例であった。上強膜炎10例、強膜炎のうち前部30例(びまん性16例、結節性7 …
- NAID 110008767970
- 小泉 範子,奥村 直毅,木下 茂
- 同志社大学理工学研究報告 52(4), [261]-266, 2012-01
- … one is by transplantation of a corneal endothelial cell sheet cultivated on a type I collagen carrier and another is by transplantation of a corneal endothelial cell sheet cultivated on a human lamellar graft prepared by a similar procedure used in DSAEK surgery. …
- NAID 110008792409
Related Links
- Type-I collagen is the most abundant collagen of the human body. It is present in scar tissue, the end product when tissue heals by repair. It is found in tendons, the endomysium of myofibrils and the organic part of bone.
- Over 90% of the collagen in the body, however, is of type one. So far, 28 types of collagen have been identified and described. The five most common types are: Collagen I: skin, tendon, vascular ...
Related Pictures
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I型コラーゲン
- 関
- collagen I、type 1 collagen、type I collagen
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I型コラーゲンC末端テロペプチド
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I型コラーゲンCテロペプチド
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- (windows)ファイル内容表示(linux -> cat])
- ex. type report_20111118.jp.htm | php a.php > report_20111118.jp.jp.jp.html
- 関
- form、mode、pattern、type specimen、typed
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- 関
- form、mode、pattern、type
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