甲状腺髄様癌
WordNet
- of or relating to the medulla of any body part
- containing or consisting of or resembling bone marrow
- of or relating to the medulla oblongata
- suggestive of a thyroid disorder; "thyroid personality"
- of or relating to the thyroid gland; "thyroid deficiency"; "thyroidal uptake" (同)thyroidal
- the inner part of an organ or structure in plant or animal
- any malignant tumor derived from epithelial tissue; one of the four major types of cancer
PrepTutorEJDIC
- 甲状腺 / 甲状腺の
- 〈U〉骨髄 / =medulla oblongata
- がん,がん腫
UpToDate Contents
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English Journal
- The International Society of Urological Pathology (ISUP) Vancouver Classification of Renal Neoplasia.
- Srigley JR, Delahunt B, Eble JN, Egevad L, Epstein JI, Grignon D, Hes O, Moch H, Montironi R, Tickoo SK, Zhou M, Argani P; The ISUP Renal Tumor Panel.Source*Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada †Department of Pathology and Molecular Medicine, Wellington School of Medicine, University of Otago, Wellington, New Zealand ‡Department of Pathology, Indiana University School of Medicine, Indianapolis, IN Departments of ∥Pathology, Urology and Oncology §§Pathology and Oncology, Johns Hopkins Medical Institutions, Baltimore, MD ††Memorial Sloan Kettering Cancer Centre, NY ‡‡Department of Pathology, in New York University Medical Centre, New York, NY §Department of Oncology and Pathology, Karolinska University Hospital Solna, Stockholm, Sweden ¶Department of Pathology, University Hospital Plzen, Plzen, Czech Republic #Institute of Surgical Pathology, University of Zurich, Switzerland **Section of Pathological Anatomy, Polytechnic University of Medicine, United Hospitals, Ancona, Italy.
- The American journal of surgical pathology.Am J Surg Pathol.2013 Oct;37(10):1469-1489.
- The classification working group of the International Society of Urological Pathology consensus conference on renal neoplasia was in charge of making recommendations regarding additions and changes to the current World Health Organization Classification of Renal Tumors (2004). Members of the group p
- PMID 24025519
- Recombinant leukemia inhibitory factor suppresses human medullary thyroid carcinoma cell line xenografts in mice.
- Starenki D, Singh NK, Jensen DR, Peterson FC, Park JI.SourceDepartment of Biochemistry, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
- Cancer letters.Cancer Lett.2013 Oct 1;339(1):144-51. doi: 10.1016/j.canlet.2013.07.006. Epub 2013 Jul 12.
- Medullary thyroid carcinoma (MTC) is a neoplasm of the endocrine system, which originates from parafollicular C-cells of the thyroid gland. For MTC therapy, the Food and Drug Administration recently approved vandetanib and cabozantinib, multi-kinase inhibitors targeting RET and other tyrosine kinase
- PMID 23856028
- The involvement of the RET variant G691S in medullary thyroid carcinoma: conflicting results of meta-analyses need to be reconciled.
- Lantieri F, Caroli F, Ceccherini I, Griseri P.
- International journal of cancer. Journal international du cancer.Int J Cancer.2013 Oct 1;133(7):1760-1. doi: 10.1002/ijc.28177. Epub 2013 Apr 22.
- PMID 23536393
Japanese Journal
- 臨床報告 高CEA血症精査中に発見されたRET遺伝子変異家族性甲状腺髄様癌の1例
- 御供 真吾,佐瀬 正博,玉澤 佳之 [他]
- 臨床外科 = Journal of clinical surgery 69(1), 102-106, 2014-01
- NAID 40019925646
- 症例報告 甲状腺全摘術を施行した多発性内分泌腫瘍症(MEN)2B型の6歳女児例
- 甲状腺髄様癌の肝転移巣からの異所性副腎皮質刺激ホルモン(ACTH)産生か疑われた多発性内分泌腺腫症2B型(MEN2B)の1例
- 黒住 旭,岡田 洋右,新生 忠司,中本 裕士,富樫 かおり,田中 良哉
- 産業医科大学雑誌 35(3), 193-199, 2013-09-01
- 症例は31歳女性で,10歳時に多発性内分泌腺腫2B型(MEN 2B)と診断された.徐々に皮膚の黒色色素沈着が広がり,副腎皮質刺激ホルモン(ACTH)高値を認め,異所性ACTH症候群の合併が疑われた.副腎皮質刺激ホルモン放出ホルモン(CRH)負荷試験ではクッシング病は否定的で,異所性ACTH症候群に矛盾しない結果であった.腹部CTで肝の多発する低吸収域を認め,ACTH産生部位として甲状腺髄様癌の肝転 …
- NAID 110009657657
★リンクテーブル★
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- 英
- medullary thyroid carcinoma MTC、medullary carcinoma of thyroid, thyroid medullary carcinoma
- 同
- 甲状腺C細胞癌、thyroid C-cell carcinoma
- 関
- アミロイドーシス、甲状腺腫瘍、甲状腺癌
概念
疫学
- 甲状腺悪性腫瘍の5～10％？ 甲状腺癌の1-2%(YN.D-41)
- 男女比はほぼ1：1 男女比=1:2(YN.D-41)
- 発症年齢は30歳代と50歳代がピーク
病型
病因
- 常染色体優性遺伝疾患の多発性内分泌腫瘍症2A型，同2B型とおなじ
病理
- 類円形から多角形のさまざまな形態をとる腫瘍細胞が、シート状、胞巣状、島状あるいは管状、濾胞状、乳頭状の構造を呈する
病態
進展様式
症状
検査
合併症
予後
参考
- 1. [charged] Clinical manifestations and staging of medullary thyroid cancer - uptodate [1]
- 2. [charged] Treatment of medullary thyroid cancer - uptodate [2]
- 3. [charged] Chemotherapy and immunotherapy for medullary thyroid cancer - uptodate [3]
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家族性甲状腺髄様癌
[★]
- 関
- bulbar、medulla、medulla oblongata
[★]
毛
副腎
脳神経
[★]
- 関
- thyroid gland、thyroidal