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WordNet
- (physical chemistry) a sample of matter in which substances in different phases are in equilibrium; "in a static system oil cannot be replaced by water on a surface"; "a system generating hydrogen peroxide"
- instrumentality that combines interrelated interacting artifacts designed to work as a coherent entity; "he bought a new stereo system"; "the system consists of a motor and a small computer"
- a group of independent but interrelated elements comprising a unified whole; "a vast system of production and distribution and consumption keep the country going" (同)scheme
- a complex of methods or rules governing behavior; "they have to operate under a system they oppose"; "that language has a complex system for indicating gender" (同)system of rules
- a group of physiologically or anatomically related organs or parts; "the body has a system of organs for digestion"
- a procedure or process for obtaining an objective; "they had to devise a system that did not depend on cooperation"
- the living body considered as made up of interdependent components forming a unified whole; "exercise helped him get the alcohol out of his system"
- (medicine) the invasion of the body by pathogenic microorganisms and their multiplication which can lead to tissue damage and disease
- (phonetics) the alteration of a speech sound under the influence of a neighboring sound
- the pathological state resulting from the invasion of the body by pathogenic microorganisms
- (international law) illegality that taints or contaminates a ship or cargo rendering it liable to seizure
- moral corruption or contamination; "ambitious men are led astray by an infection that is almost unavoidable"
- an incident in which an infectious disease is transmitted (同)contagion, transmission
- affecting an entire system; "a systemic poison"
PrepTutorEJDIC
- 〈C〉(関連した部分から成る)『体系』,系統,組織[網],装置 / 〈C〉(教育・政治などの)『制度』,機構;《the~》体制 / 〈C〉(思想・学問などの)『体系』,学説 / 〈C〉(…の)『方法』,方式,やり方《+of doing》 / 〈U〉正しい方針(筋道,順序) / 〈U〉《the~》(身体の)組織,系統 / 〈U〉《the~,one's~》身体,全身
- 〈U〉(病気の)伝染;感染 / 〈C〉伝染病
- (身体・言語のように)体系の,組織の / 全身の,全身的
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/03/04 12:05:39」(JST)
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Life-threatening disease redirects here.
A systemic disease is one that affects a number of organs and tissues, or affects the body as a whole.[1]
Contents
- 1 Examples
- 2 Detection
- 3 See also
- 4 References
Examples
- Mastocytosis, including Mast Cell Activation Disorder and Eosinophilic Esophagitis
- Chronic fatigue syndrome
- Systemic vasculitis e.g. SLE, PAN
- Sarcoidosis – a disease that mainly affects the lungs, brain, joints and eyes, found most often in young African-American women.
- Diabetes mellitus – an imbalance in blood glucose (sugar) levels.
- Ulcerative colitis – an inflammatory bowel disease
- Hypertension (high blood pressure)
- Metabolic syndrome
- AIDS – a disease caused by a virus that cripples the body’s immune defenses.
- Grave's disease – a thyroid disorder, most often in women, which can cause a goiter (swelling in the front part of the neck) and protruding eyes.
- Systemic lupus erythematosus – a connective tissue disorder involving mainly the skin, joints and kidneys.
- Rheumatoid arthritis – an inflammatory disease which mainly attacks the joints. But can also affect a person's skin, eyes, lungs and mouth.
- Atherosclerosis – a hardening of the arteries
- Sickle cell disease – an inherited blood disorder that can block circulation throughout the body, primarily affecting African-Americans
- Myasthenia gravis
Detection
Getting a regular eye exam may play a role in identifying the signs of some systemic diseases. "The eye is composed of many different types of tissue. This unique feature makes the eye susceptible to a wide variety of diseases as well as provides insights into many body systems. Almost any part of the eye can give important clues to the diagnosis of systemic diseases. Signs of a systemic disease may be evident on the outer surface of the eye (eyelids, conjunctiva and cornea), middle of the eye and at the back of the eye (retina)."[2]
Since 500 B.C., some researchers have also believed that the physical condition of the fingernails and toenails can indicate various systemic diseases. Careful examination of the fingernails and toenails may provide clues to underlying systemic diseases, since some diseases have been found to cause disruptions in the nail growth process. The nail plate is the hard keratin cover of the nail. The nail plate is generated by the nail matrix located just under the cuticle. As the nail grows, the area closest to becoming exposed to the outside world (distal) produces the deeper layers of the nail plate, while the part of the nail matrix deeper inside the finger (proximal) makes the superficial layers. Any disruption in this growth process can lead to an alteration in the shape and texture.
Take pitting, for example. Pitting looks like depressions in the hard part of the nail. Pitting usually is associated with psoriasis, affecting 10 to 50 percent of patients with that disorder.[3] Pitting also may be caused by a variety of systemic diseases, including Reiter's syndrome and other connective tissue disorders, sarcoidosis, pemphigus, alopecia areata, and incontinentia pigmenti.[4] Because pitting is caused by defective layering of the superficial nail plate by the proximal nail matrix, any localized dermatitis (e.g., atopic dermatitis or chemical dermatitis) that disrupts orderly growth in that area also can cause pitting.[5]
See also
- Disease
- Disseminated disease
- Fred Siguier
- List of systemic diseases with ocular manifestations
- Localized disease
- Marfan syndrome
- Systemic autoimmune diseases
- Systemic inflammation
References
- ^ Dorland's Illustrated Medical Dictionary,28th edition (Harcourt Brace & Company). Page 489,1653
- ^ "The Eye in Systemic Disease" (University of Illinois at Chicago: 2008), Available at: http://www.uic.edu/com/eye/LearningAboutVision/EyeFacts/SystemicDisease.shtml, Accessed 20 August 2009.
- ^ Mayeaux EJ Jr. Nail disorders. Prim Care 2000;27: 333-51.
- ^ Daniel CR 3d, Sams WM Jr, Scher RK. Nails in systemic disease. Dermatol Clin 1985;3:465-83.
- ^ Eds. ROBERT S. FAWCETT, M.D., M.S., SEAN LINFORD, M.D., and DANIEL L. STULBERG, M.D., Nail Abnormalities: Clues to Systemic Disease (American Family Physician, March 15, 2004), Available at http://www.aafp.org/afp/20040315/1417.html, Accessed 20 August 2009.
UpToDate Contents
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English Journal
- Knockout of interleukin-17A protects against sepsis-associated acute kidney injury.
- Luo CJ1,2, Luo F1,3, Zhang L4, Xu Y1, Cai GY2, Fu B2, Feng Z2, Sun XF2, Chen XM5.
- Annals of intensive care.Ann Intensive Care.2016 Dec;6(1):56. doi: 10.1186/s13613-016-0157-1. Epub 2016 Jun 22.
- BACKGROUND: Sepsis-associated acute kidney injury (SA-AKI) is an independent risk factor for death in patients with sepsis, but treatment for it is limited. To improve the diagnosis and treatment of SA-AKI, we must first understand its pathogenesis. Recently, interleukin (IL)-17A has been shown to b
- PMID 27334720
- Combination of C-reactive protein, procalcitonin and sepsis-related organ failure score for the diagnosis of sepsis in critical patients.
- Yang Y1, Xie J1, Guo F1, Longhini F1,2, Gao Z1, Huang Y1, Qiu H3.
- Annals of intensive care.Ann Intensive Care.2016 Dec;6(1):51. doi: 10.1186/s13613-016-0153-5. Epub 2016 Jun 10.
- OBJECTIVE: To measure the ability of a new bioscore to diagnose sepsis in a general critical care population.METHODS: The study was done at an intensive care unit (ICU) from April to December 2012. Demographic and clinical patient information were recorded on admission to the ICU with blood samples
- PMID 27287669
- Prognostic value of PCT in septic emergency patients.
- Peschanski N1, Chenevier-Gobeaux C2, Mzabi L3, Lucas R1, Ouahabi S4, Aquilina V1, Brunel V5, Lefevre G4, Ray P3,6.
- Annals of intensive care.Ann Intensive Care.2016 Dec;6(1):47. doi: 10.1186/s13613-016-0146-4. Epub 2016 May 21.
- BACKGROUND: An accurate assessment of septic patients at risk for poor clinical outcomes is challenging for clinicians in the emergency department (ED).OBJECTIVES: We aimed to evaluate the prognostic value of procalcitonin (PCT) in septic patients in the ED for predicting death.RESULTS: In a retrosp
- PMID 27207179
Japanese Journal
- 斜台骨髄炎と海綿静脈洞部腫瘤性病変を呈しステロイドが奏功したLemierre症候群の1例
- 高橋 正太郎,伊藤 悟,田頭 秀悟,安井 建一,渡辺 保裕,中島 健二
- 臨床神経学 55(5), 327-332, 2015
- 症例は73歳男性である.発熱と後頭部痛,眼球運動障害,複視,右眼瞼下垂のために入院となった.入院後に頭痛と眼症状の増悪がみられ,意識障害を呈した.頭部MRIでは斜台部造影増強効果と鞍上部・海綿静脈洞部に造影増強効果をもつ腫瘤性病変をみとめ,頸部CTでは左内頸静脈の血栓性閉塞をみとめた.血液培養結果からFusobacterium nucleatumによるLemierre症候群と診断し,抗菌薬と経口ス …
- NAID 130005073099
- Pulmonary Metastasis of Combined Hepatocellular and Cholangiocarcinoma: A Unique Radiographic Presentation with Air-space Consolidation Masquerading as Pneumonia and Primary Pulmonary Adenocarcinoma
- , , , , , , , ,
- Internal Medicine 54(11), 1389-1392, 2015
- … The pulmonary lesion was initially suspected to be infection and later clinically diagnosed as primary adenocarcinoma of the lung. … Although the patient was treated with systemic chemotherapy, the disease progressed very rapidly. …
- NAID 130005072929
- Isoniazid-induced Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Presenting as Acute Eosinophilic Myocarditis
- , , , ,
- Internal Medicine 54(10), 1227-1230, 2015
- … During therapy, he suffered from drug rash with eosinophilia and systemic symptoms (DRESS) presenting as acute eosinophilic myocarditis, as confirmed on a histopathologic examination. …
- NAID 130005069785
Related Links
- systemic infection Etymology: Gk, systema + L, inficere, to stain an infection in which the pathogen is distributed throughout the body rather than concentrated in one area. infection 1. invasion and multiplication of microorganisms in ...
- Systemic infection is a generic term for infection caused by microorganisms in animals or plants, where the causal agent (the microbe) has spread actively or passively in the host's anatomy and is disseminated throughout several ...
Related Pictures
★リンクテーブル★
[★]
- 英
- systemic infection
- 関
- 全身感染症、全身性感染症
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- 英
- systemic infection
- 関
- 全身感染症、全身感染
[★]
- 関
- general、generalized、systemically、total body、whole body、whole-body
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- 関
- contagion、infect、infectious disease、infestation、transmission、transmit
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- 関
- method、series、strain