WordNet

of primary importance (同)primary
serving as or forming a base; "the painter applied a base coat followed by two finishing coats" (同)base
one of several parallel layers of material arranged one on top of another (such as a layer of tissue or cells in an organism or a layer of sedimentary rock)

PrepTutorEJDIC

基底の,基部の / 基礎的な,基本的な
地層,岩層 / (社会的な)階層

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/02/05 18:28:52」(JST)

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Histologic image showing a section of epidermis. Stratum basale labeled near bottom.

The stratum basale (basal layer, sometimes referred to as stratum germinativum) is the deepest layer of the five layers of the epidermis, which is the outer covering of skin in mammals.

The stratum basale is a continuous layer of cells. It is often described as one cell thick, though it may in fact be two to three cells thick in glabrous (hairless) skin and hyperproliferative epidermis (from a skin disease).^[1]

The stratum basale is primarily made up of basal keratinocyte cells, which can be considered the stem cells of the epidermis. They divide to form the keratinocytes of the stratum spinosum, which migrate superficially.^[2] Other types of cells found within the stratum basale are melanocytes (pigment-producing cells), Langerhans cells (immune cells), and Merkel cells (touch receptors).

Additional images[edit]

Epidermis and dermis of human skin
Section of epidermis

References[edit]

^ McGrath, J.A.; Eady, R.A.; Pope, F.M. (2004). Rook's Textbook of Dermatology (Seventh Edition). Blackwell Publishing. Pages 3.7. ISBN 978-0-632-06429-8.
^ Habif, Thomas P. (2010). Clinical Dermatology, 5th ed. Mosby. p. 1. ISBN 978-0-7234-3541-9.

UpToDate Contents

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1. ダリエ病 darier disease
2. 植皮と人工皮膚 skin grafting and skin substitutes
3. アトピー性皮膚炎（湿疹）：発症機序、臨床症状、診断 atopic dermatitis eczema pathogenesis clinical manifestations and diagnosis
4. 顆粒性不全角化 granular parakeratosis
5. 皮膚剥脱症候群 peeling skin syndrome

English Journal

Effect of sample preparation techniques on the concentrations and distributions of elements in biological tissues using µSRXRF: a comparative study.

Al-Ebraheem A1, Dao E, Desouza E, Li C, Wainman BC, McNeill FE, Farquharson MJ.
Physiological measurement.Physiol Meas.2015 Mar;36(3):N51-60. doi: 10.1088/0967-3334/36/3/N51. Epub 2015 Feb 13.
Routine tissue sample preparation using chemical fixatives is known to preserve the morphology of the tissue being studied. A competitive method, cryofixation followed by freeze drying, involves no chemical agents and maintains the biological function of the tissue. The possible effects of both samp
PMID 25679963

Pseudoepitheliomatous hyperplasia mimicking invasive squamous cell carcinoma in extranodal natural killer/T-cell lymphoma: a report of 34 cases.

Ling YH1, Zhu CM, Wen SH, Luo RZ, Li P, Cao Y, Rao HL, Lin SX, Cai MY.
Histopathology.Histopathology.2015 Jan 25. doi: 10.1111/his.12656. [Epub ahead of print]
AIMS: Pseudoepitheliomatous hyperplasia (PEH) is defined as a pattern of epidermal reaction. However, it has not yet been extensively documented in extranodal natural killer/T-cell lymphoma (ENKTL). The aim of our study was to analyse a series of ENKTLs concomitant with PEH mimicking squamous cell c
PMID 25619876

hMSH6: a potential diagnostic marker for oral carcinoma in situ.

Jessri M1, Dalley AJ1, Farah CS2.
Journal of clinical pathology.J Clin Pathol.2015 Jan;68(1):86-90. doi: 10.1136/jclinpath-2014-202411. Epub 2014 Oct 28.
Oral medicine specialists rely upon accurate assessment of pathology to rationalise lesion management, especially for high-risk oral epithelial dysplasia, carcinoma in situ (CIS) and oral squamous cell carcinoma. Cross-discipline cancer research has highlighted the role of genetic instability in neo
PMID 25352643

Japanese Journal

Alteration in the Apoptosis Process of Rat Esophageal Epithelium with Hyperproliferation of Indigenous Bacteria under a Physiological Condition

UDAYANGA Kankanam Gamage Sanath,YAMAMOTO Kyoji,MIYATA Hidenori [他],YOKOO Yuh,MANTANI Youhei,TAKAHARA Ei-ichrou,KAWANO Junichi,YOKOYAMA Toshifumi,HOSHI Nobuhiko,KITAGAWA Hiroshi
Journal of Veterinary Medical Science 74(5), 597-605, 2012
… As a result, Fas and Fas-L were expressed in the epithelial cell membrane and cytoplasm from the stratum spinosum (SS) to the stratum granulosum (SG). … Cytochrome c was observed as cytoplasmic granular positivity from the stratum basale (SB) and altered into homogeneous immunopositivity in the SG. … Prominently swollen cells and decreased mitochondria were ultrastructurally confirmed in the uppermost layers of stratum corneum. …
NAID 130001879887

Expression of TRPV4 in the Stimulated Rat Oral Mucous Membrane-Nociceptive Mechanisms of Lingual Conical Papillae-

NAKATSUKA Michiko,IWAI Yasutomo
Okajimas Folia Anatomica Japonica 86(2), 45-54, 2009
… Specimens of the experimental IDLE demonstrated a significant increase of TRPV4 activity in particular in stratum basale of conical papillae (p < …
NAID 130004773582

生体表皮下の高精細ＯＣＴ

近江雅人,春名正光
日本レーザー医学会誌 26(3), 239-244, 2005
光コヒーレンストモグラフィ（OCT）は生体表皮下の高分解能断層イメージング手法として臨床上極めて有望な技術である．しかしながら，現状のOCTは組織切片の顕微鏡写真と比較して高精細化に関して改善すべき課題がある．本論文では，高精細OCTに向けての我々のアプローチを紹介する．インフォーカスOCTを用いたヒト胃壁のイメージングにおいては，厚さ数10μmの粘膜筋板を鮮明に描出することができた．さらに，フェ …
NAID 130004491957