oxazolidinone antibacterial agents

オキサゾリジノン系合成抗菌薬

WordNet

1. a substance that exerts some force or effect
2. a businessman who buys or sells for another in exchange for a commission (同)factor, broker
3. any agent or representative of a federal agency or bureau (同)federal agent
4. a representative who acts on behalf of other persons or organizations
5. an active and efficient cause; capable of producing a certain effect; "their research uncovered new disease agents"
6. any drug that destroys bacteria or inhibits their growth (同)antibacterial_drug, bactericide
7. destroying bacteria or inhibiting their growth

PrepTutorEJDIC

1. 『代理人』;周旋人 / 働き(作用)を起こすもの;作用物,薬剤 / (政府機関,特にFBI,CIAなどの)部員,機関員

UpToDate Contents

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• 5. 成人における迅速導入気管挿管のための鎮静剤または導入剤 sedation or induction agents for rapid sequence intubation in adults

English Journal

• Chiral separation of tedizolid using charge single isomer derivatives of cyclodextrins by capillary electrokinetic chromatography.

• Michalska K1, Gruba E2, Cielecka-Piontek J3, Bednarek E4.
• Journal of pharmaceutical and biomedical analysis.J Pharm Biomed Anal.2015 Dec 24. pii: S0731-7085(15)30241-7. doi: 10.1016/j.jpba.2015.11.022. [Epub ahead of print]
• A method to enantioseparate tedizolid (TED), the second analogue after linezolid (LIN) in a truly new class of antibacterial agents, the oxazolidinones, was developed based on capillary electrokinetic chromatography using cyclodextrin as chiral pseudophase (CD-cEKC). The single isomer R-tedizolid po
• PMID 26724911

• Synthesis and biological evaluation of novel 5-(hydroxamic acid)methyl oxazolidinone derivatives.

• Phillips OA1, D'Silva R2, Bahta TO3, Sharaf LH4, Udo EE5, Benov L6, Eric Walters D7.
• European journal of medicinal chemistry.Eur J Med Chem.2015 Dec 1;106:120-31. doi: 10.1016/j.ejmech.2015.10.025. Epub 2015 Oct 23.
• Research activities on the oxazolidinone antibacterial class of compounds continue to focus on developing newer derivatives with improved potency, broad-spectrum activity and safety profiles superior to linezolid. Among the safety concerns with the oxazolidinone antibacterial agents is inhibition of
• PMID 26536532

• Evaluation of the Efficacy of Novel Oxazolidinone Analogues against Nontuberculous Mycobacteria In Vitro.

• Zhao W1, Jiang Y, Bao P, Li Y, Tang L, Zhou Y, Zhao Y.
• Japanese journal of infectious diseases.Jpn J Infect Dis.2015 Nov 20;68(6):520-2. doi: 10.7883/yoken.JJID.2014.498. Epub 2015 May 12.
• Nontuberculous mycobacteria (NTM) are associated with a number of clinical diseases and only a few antitubercular agents are active against them. Oxazolidinones comprise a novel class of antimicrobials that inhibit bacterial protein synthesis at the ribosome. Linezolid, the first oxazolidinone antib
• PMID 25971324

Japanese Journal

• Evaluation of the Efficacy of Novel Oxazolidinone Analogues against Nontuberculous Mycobacteria In Vitro

• Japanese Journal of Infectious Diseases 68(6), 520-522, 2015
• NAID 130005109799

• Evaluation of the in vitro efficacy of novel oxazolidinone analogues against Nontuberculous mycobacteria

• Japanese Journal of Infectious Diseases advpub(0), 2015
• NAID 130005069406

• Synthesis and in Vitro Evaluation of the Antitubercular and Antibacterial Activity of Novel Oxazolidinones Bearing Octahydrocyclopenta[c]pyrrol-2-yl Moieties

• Chemical and Pharmaceutical Bulletin 62(12), 1214-1224, 2014
• NAID 130004693782

Related Links

• Oxazolidinone Antibacterial Agents - Springer

The “golden age” of antibacterial agent discovery commenced with the identification of the sulfa drugs in the mid 1930s and concluded with the emergence of the quinolones in the early 1960s (Fig. 8.1)

• Oxazolidinone antibacterial agents: a critical review.

1. Curr Top Med Chem. 2003;3(9):1021-42. Oxazolidinone antibacterial agents: a critical review. Hutchinson DK. Infectious Diseases Research, Abbott Laboratories, 200 Abbott Park Rd, Abbott Park, IL 60064-6217, USA. douglas ...

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★リンクテーブル★

リンク元	「オキサゾリジノン系合成抗菌薬」
関連記事	「agent」「antibacterial」

「オキサゾリジノン系合成抗菌薬」

　　[★]

英

oxazolidinone antibiotic, oxazolidinone antibacterial agents

関

抗菌薬

• リネゾリド(ザイボックス)
• テジゾリド(シベクトロ)

「agent」

　　[★]

• n.

• 代行者、代理人。代理業者
• 政府職員、官吏
• ある後位をする人、ある作用をするもの。動員、動力因、作用因。(文法)動作主。科学的変化を起こさせるもの、薬品、～剤。病原体

関

agonist、agonistic、attorney、delegate、drug、etiologic agent、fomes、fomites、mediator、pathogen、pathogenic、pharmaceutical preparation、vector、vehicle

　 　 　 　 　 　

「antibacterial」

　　[★]

• adj.

• 抗菌性の、抗菌的な、抗菌の

• n.

• 抗菌薬

関

anti-bacterial agent、antibacterial agent、antibacterial drug、antibacterially、antibacterials、antibiotic、antibiotics、antimicrobial、antimicrobial agent、antimicrobials