ovarian tumor

卵巣腫瘍

WordNet

1. of or involving the ovaries; "ovarian cancer"
2. an abnormal new mass of tissue that serves no purpose (同)tumour, neoplasm

PrepTutorEJDIC

1. 卵巣の / 子房(しぼう)の

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/05/04 15:23:10」(JST)

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[Wiki en表示]

Ovarian tumors, or ovarian neoplasms, are tumors arinsing from the ovary. They can benign or malignant (ovarian cancer).

Benign tumors

A benign tumor of the ovary, discovered during a C-section; this is a 4 cm teratoma

Further information: Ovarian cyst

Benign tumors of the ovary include ovarian cysts, such as borderline tumor cysts.

Cancer

A pathological specimen of ovarian carcinoma.

Main article: Ovarian cancer

Ovarian cancer is classified according to the histology of the tumor, obtained in a pathology report. Histology dictates many aspects of clinical treatment, management, and prognosis.

• Surface epithelial-stromal tumours, also known as ovarian epithelial tumors, are the most common type of ovarian cancer. It includes serous tumour, endometrioid tumor, and mucinous tumour. They can be benign (cystadenoma) or malignant (cystadenocarcinoma). Less common tumors are malignant Brenner tumor and transitional cell carcinoma of the ovary.
• Sex cord-stromal tumor, including estrogen-producing granulosa cell tumor and virilizing Sertoli-Leydig cell tumor or arrhenoblastoma, accounts for 8% of ovarian cancers.
• Germ cell tumor accounts for approximately 30% of ovarian tumors but only 5% of ovarian cancers, because most germ cell tumors are teratomas and most teratomas are benign. Germ cell tumors tend to occur in young women (20's-30's) and girls. Whilst overall the prognosis of germ cell tumors tend to be favourable, it can vary substantially with specific histology: for instance, the prognosis of the most common germ cell tumor (dysgerminomas) tends to be good, whilst the second most common (endodermal sinus tumor) tends to have a poor prognosis. In addition, the cancer markers used vary with tumor type: choriocarcinomas are monitored with beta-HCG; dysgerminomas with LDH; and endodermal sinus tumors with alpha-fetoprotein.
• Mixed tumors, containing elements of more than one of the above classes of tumor histology.

UpToDate Contents

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• 1. 付属器腫瘤の鑑別診断 differential diagnosis of the adnexal mass
• 2. Borderline ovarian tumors
• 3. 付属器腫瘤のマネージメント management of an adnexal mass
• 4. 付属器腫瘤をもつ患者に対するアプローチ approach to the patient with an adnexal mass
• 5. 卵巣癌、卵管癌、および腹膜癌：病期分類および初期外科的マネージメント cancer of the ovary fallopian tube and peritoneum staging and initial surgical management

English Journal

• Hyperplasia in glands with hormone excess.

• Marx SJ1.
• Endocrine-related cancer.Endocr Relat Cancer.2016 Jan;23(1):R1-R14. doi: 10.1530/ERC-15-0171. Epub 2015 Sep 25.
• Five syndromes share predominantly hyperplastic glands with a primary excess of hormones: neonatal severe primary hyperparathyroidism, from homozygous mutated CASR, begins severely in utero; congenital non-autoimmune thyrotoxicosis, from mutated TSHR, varies from severe with fetal onset to mild with
• PMID 26407873

• RUNX3 and CAMK2N1 hypermethylation as prognostic marker for epithelial ovarian cancer.

• Häfner N1, Steinbach D1, Jansen L1, Diebolder H1, Dürst M1, Runnebaum IB1.
• International journal of cancer. Journal international du cancer.Int J Cancer.2016 Jan 1;138(1):217-28. doi: 10.1002/ijc.29690. Epub 2015 Jul 28.
• Treatment of epithelial ovarian cancer consists of surgery plus platinum-taxane based chemotherapy. Neither prognostic nor predictive serum or tissue markers except BRCA1/2 mutations are available thus precluding individualized treatment. Aim of this study is the identification and validation of DNA
• PMID 26175272

• A Decision Tree Based Classifier to Analyze Human Ovarian Cancer cDNA Microarray Datasets.

• Tsai MH1,2, Wang HC3, Lee GW4, Lin YC5, Chiu SH6.
• Journal of medical systems.J Med Syst.2016 Jan;40(1):21. doi: 10.1007/s10916-015-0361-9. Epub 2015 Nov 3.
• Ovarian cancer is the deadliest gynaecological disease because of the high mortality rate and there is no any symptom in cancer early stage. It was often the terminal cancer period when patients were diagnosed with ovarian cancer and thus delays a good opportunity of treatment. The current common me
• PMID 26531754

Japanese Journal

• 症例報告 閉経後に多量の腹腔内貯留液を伴って発見された巨大卵巣血腫の症例

• 角張 玲沙,小西 恒,田中 江里子 [他]
• 産婦人科の進歩 67(1), 14-20, 2015-02
• NAID 40020342668

• 症例報告 CTが卵巣腫瘍との鑑別診断に有用であった後腹膜原発脂肪肉腫の一例

• 佐久間 有加,川野 みどり,木嶋 由理子 [他]
• 千葉県産科婦人科医学会雑誌 = Chiba journal of obstetrics and gynecology 8(2), 127-130, 2015
• NAID 40020334907

• 化学療法抵抗性卵巣癌の局所免疫の解析に基づいた,がん免疫逃避を標的とした新規治療戦略(シンポジウム2(腫瘍) 難治性卵巣癌の克服を目指して,第66回日本産科婦人科学会学術講演会講演要旨)

• 濱西 潤三
• 日本産科婦人科學會雜誌 66(11), 2777-2791, 2014-11-01
• … Background: Ovarian cancer is the most lethal gynecologic malignancy in the world and the fourth most common cause of cancer death in women, largely because more than 75% of patients are diagnosed at advanced tumor status (stage III or IV). … Although taxane and platinum-based chemotherapies are effective in the treatment of the majority of ovarian cancer cases, over 70% of patients suffer from recurrence and eventually develop chemo-resistance. …
• NAID 110009872637

Related Links

• Ovarian Cysts and Tumors - Symptoms, Causes, and ...

WebMD provides a comprehensive look at ovarian cysts and tumors - their types and symptoms and how they are diagnosed and treated. ... The ovaries are two small organs located on either side of the uterus in a woman’s body.

• Ovarian tumor - definition of Ovarian tumor by Medical dictionary

What is Ovarian tumor? Meaning of Ovarian tumor medical term. What does Ovarian tumor mean? Ovarian tumor - definition of Ovarian tumor by Medical dictionary http://medical-dictionary.thefreedictionary.com/Ovarian+tumor ...

Related Pictures

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★リンクテーブル★

リンク元	「卵巣腫瘍」「卵巣腫」「ovarian mass」
拡張検索	「benign ovarian tumor」
関連記事	「ovarian」「tumor」

「卵巣腫瘍」

　　[★]

英

ovarian tumor

関

産婦人科学、腫瘍、卵巣奇形腫、卵巣腫瘍の腫瘍マーカー、卵巣癌

概念

• 卵巣に発生する腫瘍であり、80%が良性といわれる。良性のものは嚢胞性腫瘍が多く、悪性の腫瘍は充実性のものが大半である。

分類

• 原発による分類

• 卵巣原発
• 転移性：クルケンベルグ腫瘍

• 組織による分類

疫学

• 悪性の卵巣腫瘍は漿液性腫瘍、類内膜癌、粘液性腫瘍が多い。
• 若いころの卵巣腫瘍は奇形腫、腺腫が多い
• 50-69歳の女性で多発

• 顆粒膜細胞腫は卵巣腫瘍中4.6%でホルモン産生腫瘍のなかで最多(QB.Q-302)

好発年齢

• 若年者に多い：

• セルトリ・間質細胞腫瘍、ライディッヒ細胞種
• 成熟嚢胞性奇形腫、未熟奇形腫、未分化胚細胞腫

卵巣腫瘍の組織分類

• 1)表層上皮性・間質性腫瘍 Surface epithelial-stromal tumors

• 粘液性腫瘍
• 粘液性腫瘍
• 類内膜腫瘍
• 明細胞腫瘍

• 2)性索間質性腫瘍 Sex cord/stromal tumors

• 顆粒膜・間質細胞腫瘍
• セルトリ・間質細胞腫瘍

• 3)幹細胞腫癌 Germ cell tumors

• 未分化幹細胞腫瘍
• 卵黄嚢腫瘍
• 胎芽性癌
• 絨毛癌
• 奇形腫(成熟型、未熟型)

	良性腫瘍	境界悪性腫瘍	悪性腫瘍
表層上皮性 ・ 間質性腫瘍	漿液性嚢胞腺腫	漿液性嚢胞性腫瘍,境界悪性[低悪性度腫瘍]	漿液性腺癌[漿液性嚢胞腺癌]
	粘液性嚢胞腺腫	粘液性嚢胞性腫瘍(同上)	粘液性腺癌[粘液性嚢胞腺癌]
	明細胞腺腫	類内膜腫瘍(同上)	類内膜腺癌
	類内膜腺腫	明細胞腫瘍(同上)	明細胞腺癌
	腺線維腫(上記の各型)	腺線維腫(上記の各型)	腺癌線維腫(上記の各型)
	表在性乳頭腫	表在性乳頭状腫瘍,境界悪性[低悪性度腫瘍]	腺肉腫
			中胚芽性混合腫瘍 [Muller管混合腫瘍] [癌肉腫]
	Brenner腫瘍	Brenner腫瘍,境界悪性[増殖性]	悪性Brenner腫瘍
			移行上皮癌
			未分化癌
性索間質性腫瘍	莢膜細胞腫	顆粒膜細胞腫	線維肉腫
	線維腫	Sertoli-間質細胞腫瘍(中分化型)	Sertoli-間質細胞腫瘍(低分化型)
	硬化性間質性腫瘍	ステロイド[脂質]細胞腫瘍(分類不能型)
	Sertoli-間質細胞腫瘍(高分化型)	ギナンドロブラス卜ーマ
	Leydig細胞腫 [門細胞腫]
	輪状細管を伴う性索腫瘍
胚細胞腫瘍	成熟嚢胞性奇形腫(皮様嚢胞腫)	未熟奇形腫(G1,G2)	未分化胚細胞腫
	成熟充実性奇形腫	力ルチノイド	卵黄嚢腫瘍(内胚葉洞腫瘍)
	卵巣甲状腺腫	甲状腺腫性力ルチノイド	胎芽性癌(胎児性癌)
			多胎芽腫
			悪性転化を伴う成熟嚢胞性奇形腫
			未熟奇形腫(G3)
その他	非特異的軟部腫瘍	性腺芽腫(純粋型)	癌腫
	腺腫様腫瘍		肉腫
			悪性リンパ腫(原発性)
			二次性[転移性]腫瘍
(日本産科婦人科学会・日本病理学会編‥卵巣腫瘍取扱い規約.全原出版,1990より)

妊娠に合併した卵巣腫瘍

G10M.154

• 発生率：全妊娠中の0.5%
• 病理組織：悪性腫瘍は5%未満で成熟嚢胞性奇形腫が最も多い。
• 管理：

• 妊娠10-12週までは胎児の器官形成期であるため手術を施行しない
• 妊娠14週まで経過観察し消退するようであれば、ルテイン嚢胞であり手術の必要はない。
• 妊娠14週以降には卵巣を摘出を行う。
• 以下の場合には、週数によらず手術の適応となる：茎捻転、腫瘍破裂。悪性が疑われる場合。

参考

• 1. C．産婦人科検査法 9．婦人科疾患のMRI 診断 - 日産婦誌59巻5号

http://www.jsog.or.jp/PDF/59/5905-113.pdf

• 2. E．婦人科疾患の診断・治療・管理 8．腫瘍と類腫瘍 - 日産婦誌61巻5号

http://www.jsog.or.jp/PDF/61/6105-165.pdf

「卵巣腫」

　　[★]

英

ovarian tumor、ovarian mass

関

卵巣腫瘍、卵巣腫瘤

「ovarian mass」

　　[★]

卵巣腫瘤、卵巣腫

関

ovarian tumor

「benign ovarian tumor」

　　[★]

• 卵巣良性腫瘍、良性卵巣腫瘍、良性卵巣腫

「ovarian」

　　[★]

• adj.

• 卵巣の、(植物)子房の

関

ovary

　 　

「tumor」

　　[★]

• n.

• 腫瘍、腫瘤、腫脹