organic cation transporter

同

OCT

WordNet

1. simple and healthful and close to nature; "an organic lifestyle"
2. a fertilizer that is derived from animal or vegetable matter (同)organic fertilizer, organic fertiliser
3. being or relating to or derived from or having properties characteristic of living organisms; "organic life"; "organic growth"; "organic remains found in rock"
4. involving or affecting physiology or bodily organs; "an organic disease"
5. of or relating to foodstuff grown or raised without synthetic fertilizers or pesticides or hormones; "organic eggs"; "organic vegetables"; "organic chicken"
6. relating or belonging to the class of chemical compounds having a carbon basis; "hydrocarbons are organic compounds"
7. move something or somebody around; usually over long distances
8. an exchange of molecules (and their kinetic energy and momentum) across the boundary between adjacent layers of a fluid or across cell membranes
9. move while supporting, either in a vehicle or in ones hands or on ones body; "You must carry your camping gear"; "carry the suitcases to the car"; "This train is carrying nuclear waste"; "These pipes carry waste water into the river" (同)carry
10. transport commercially (同)send, ship
11. wind instrument whose sound is produced by means of pipes arranged in sets supplied with air from a bellows and controlled from a large complex musical keyboard (同)pipe_organ
12. a fully differentiated structural and functional unit in an animal that is specialized for some particular function
13. a government agency or instrument devoted to the performance of some specific function; "The Census Bureau is an organ of the Commerce Department"
14. a periodical that is published by a special interest group; "the organ of the communist party"
15. a long truck for carrying motor vehicles (同)car transporter
16. a crane for moving material with dispatch as in loading and unloading ships
17. a positively charged ion

PrepTutorEJDIC

1. 有機体の,生物の,生物から生じた / (動植物の)器官の / 有機肥料を用いる(を用いて育った)・有機的な,組織的な,系統的な・有機質の
2. (ある場所からある場所へ)…‘を'『輸送する』,運搬する《+名+from+名+to+名》 / 《文》《受動態で》(…で)…‘を'夢中にする,有頂天にする《+名+with+名》 / 〈罪人〉‘を'流刑にする / 〈U〉輸送,運送,輸送(交通)機関(transportation) / 〈C〉(軍隊や軍需品を運ぶ)輸送船,輸送機
3. 『オルガン』,パイプオルガン(pipe organ),リードオルガン(reed organ),電子オルガン(electronic organ),手回しオルガン(barrel organ) / (動植物の)『器官』 / (政党・会社などの)機関誌,機関紙 / 《しばしば複数形で》(行動・実施などの)組織,機関
4. 自動車運搬用大型トラック
5. 陽イオン,正イオン

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/05/29 10:43:41」(JST)

wiki en

[Wiki en表示]

An organic cation transport protein mediates the transport of organic cations across the cell membrane. These proteins are members of the solute carrier family, subfamily 22. This family of proteins can also transport zwitterions and anions, though it is a different subfamily of solute carrier proteins than the organic anion transporters.

Proteins

Abbreviation	Protein name	Location	Transported solute(s)	Associated disorder(s)
SLC22A1	Solute carrier family 22 member 1	Liver, Brain (Cerebellum)
SLC22A2	Solute carrier family 22 member 2	Primarily in kidney, also in brain
SLC22A3	Solute carrier family 22 member 3	Brain and kidney	Histamine Dopamine Serotonin Norepinephrine MPP+
SLC22A4	Solute carrier family 22 member 4		Sodium ion and Ergothioneine
SLC22A5	Solute carrier family 22 member 5			Primary carnitine deficiency
SLC22A6	Solute carrier family 22 member 6
SLC22A7	Solute carrier family 22 member 7
SLC22A8	Solute carrier family 22 member 8
SLC22A9	Solute carrier family 22 member 9
SLC22A10	Solute carrier family 22 member 10
SLC22A11	Solute carrier family 22 member 11
SLC22A12	Solute carrier family 22 member 12	Kidney	Uric acid	Hyperuricemia and hypouricemia
SLC22A13	Solute carrier family 22 member 13
SLC22A14	Solute carrier family 22 member 14
SLC22A15	Solute carrier family 22 member 15
SLC22A16	Solute carrier family 22 member 16
SLC22A17	Solute carrier family 22 member 17
SLC22A18	Solute carrier family 22 member 18			Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer
SLC22A19	Solute carrier family 22 member 19
SLC22A20	Solute carrier family 22 member 20

References

UpToDate Contents

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• 1. 脂質およびプリン代謝障害による代謝性ミオパチー metabolic myopathies caused by disorders of lipid and purine metabolism
• 2. シスプラチン腎障害 cisplatin nephrotoxicity
• 3. 猫からの人畜共通感染症 zoonoses from cats
• 4. 新生児における筋緊張低下を引き起こす末梢神経および筋肉の障害に関する概要 overview of peripheral nerve and muscle disorders causing hypotonia in the newborn
• 5. 喘息およびアレルギー性鼻炎の治療におけるアレルゲン回避策 allergen avoidance in the treatment of asthma and allergic rhinitis

English Journal

• Changes in the expression of HSL and OCTN2 in the female reproductive tract of the bat, Scotophilus heathii in relation to sperm storage.

• Roy VK, Krishna A.SourceDepartment of Zoology, Banaras Hindu University, Varanasi, India.
• Acta histochemica.Acta Histochem.2012 Jul;114(4):358-62. Epub 2011 Aug 4.
• The aim of this study was to compare the changes in the expression of hormone sensitive lipase (HSL) and organic cation transporter 2 (OCTN2) in different regions of the female reproductive tract of bats (Scotophilus heathii) during the period of sperm storage. Western blot analysis revealed that bo
• PMID 21820160

• Molecular and functional identification of organic anion transporter isoforms in cultured bovine mammary epithelial cells (BME-UV).

• Al-Bataineh MM, Van Der Merwe D, Schultz BD, Gehring R.SourceDepartment of Clinical Sciences, Kansas State University, Manhattan, KS, USA Department of Diagnostic Medicine/Pathobiology, Kansas State University, Manhattan, KS, USA Department of Anatomy and Physiology, Kansas State University, Manhattan, KS, USA.
• Journal of veterinary pharmacology and therapeutics.J Vet Pharmacol Ther.2012 Jun;35(3):209-15. doi: 10.1111/j.1365-2885.2011.01309.x. Epub 2011 May 30.
• Al-Bataineh, M. M., van der Merwe, D., Schultz, B. D., Gehring, R. Molecular and functional identification of organic anion transporter isoforms in cultured bovine mammary epithelial cells (BME-UV). J. vet. Pharmacol. Therap. 35, 209-215. Mammary epithelial cells express a diversity of membrane tra
• PMID 21623837

Japanese Journal

• The predictive value of human organic cation transporter 1 and ABCB1 expression levels in different cell populations of patients with de novo chronic myelogenous leukemia

• RAZGA Filip,RACIL Zdenek,POLAKOVA Katerina Machova,BURESOVA Lucie,KLAMOVA Hana,ZACKOVA Daniela,DVORAKOVA Dana,POLIVKOVA Vaclava,CETKOVSKY Petr,MAYER Jiri
• International journal of hematology 94(3), 303-306, 2011-09-01
• NAID 10029694460

• Pdz adaptors: Their regulation of epithelial transporters and involvement in human diseases

• Sugiura Tomoko,Shimizu Takuya,Kijima Ai,Minakata Sosuke,Kato Yukio
• Journal of Pharmaceutical Sciences 100(9), 3620-3635, 2011-09
• … Although most of the evidences for transporter-adaptor interaction has been obtained in vitro, recent studies suggest that adaptor-mediated transporter regulation does occur in vivo and could be relevant to human diseases. … Thus, protein-protein interaction is not only associated with the formation of macromolecular complexes but is also involved in various cellular events, and may provide transporters with additional functionality by forming transporter networks on plasma membranes. …
• NAID 120003308592

Related Links

• Organic cation transporters. - National Center for ...

1. Rev Physiol Biochem Pharmacol. 2003;150:36-90. Epub 2003 Jun 25. Organic cation transporters. Koepsell H(1), Schmitt BM, Gorboulev V. Author information: (1)Institut für Anatomie und Zellbiologie, Bayerischen Julius ...

• Organic cation transporters (OCTs, MATEs), in vitro and in vivo ...

1. Handb Exp Pharmacol. 2011;(201):105-67. doi: 10.1007/978-3-642-14541-4_3. Organic cation transporters (OCTs, MATEs), in vitro and in vivo evidence for the importance in drug therapy. Nies AT(1), Koepsell H, Damme K, Schwab ...

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★リンクテーブル★

リンク元	「OCT」「solute carrier transporter」
拡張検索	「organic cation transporter 1」
関連記事	「transport」「organic」「transporter」「cation transporter」「cation」

「OCT」

　　[★]

• 光干渉断層撮影 optical coherence tomography
• organic cation transporter
• オキシトシンチャレンジテスト oxytocin challenge test

「solute carrier transporter」

　　[★] 溶質輸送体, SLC

関

organic cation transporter

「organic cation transporter 1」

　　[★]

有機カチオン輸送体1、有機カチオントランス・ーター1

関

OCT1

「transport」

　　[★]

• n.

• 輸送、運搬

• v.

• 輸送する、運搬する、運ぶ

関

bring、carriage、carry、convey、delivery、ship、traffic、trafficking、transportation

　 　 　 　 　

「organic」

　　[★]

• adj.

• 有機物の、有機の、有機的な、器質性の、器質的な

関

organic compound、organic matter、organized、organo

　 　 　 　 　 　 　

「transporter」

　　[★] トランスポーター

関

translocator、transport protein、transporter protein

　 　 　

「cation transporter」

　　[★]

• カチオントランス・ーター、陽イオン輸送体

関

cation transport protein

「cation」

　　[★]

• 陽イオン、カチオン

関

cationic

関

See also specific cations