- カチオントランス・ーター、陽イオン輸送体
WordNet
- move something or somebody around; usually over long distances
- an exchange of molecules (and their kinetic energy and momentum) across the boundary between adjacent layers of a fluid or across cell membranes
- move while supporting, either in a vehicle or in ones hands or on ones body; "You must carry your camping gear"; "carry the suitcases to the car"; "This train is carrying nuclear waste"; "These pipes carry waste water into the river" (同)carry
- transport commercially (同)send, ship
- a long truck for carrying motor vehicles (同)car transporter
- a crane for moving material with dispatch as in loading and unloading ships
- a positively charged ion
PrepTutorEJDIC
- (ある場所からある場所へ)…‘を'『輸送する』,運搬する《+名+from+名+to+名》 / 《文》《受動態で》(…で)…‘を'夢中にする,有頂天にする《+名+with+名》 / 〈罪人〉‘を'流刑にする / 〈U〉輸送,運送,輸送(交通)機関(transportation) / 〈C〉(軍隊や軍需品を運ぶ)輸送船,輸送機
- 自動車運搬用大型トラック
- 陽イオン,正イオン
UpToDate Contents
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- 1. Chapter 3C：近位尿細管における分泌経路 chapter 3c secretory pathways in proximal tubule
- 2. 猫からの人畜共通感染症 zoonoses from cats
- 3. シスプラチン腎障害 cisplatin nephrotoxicity
- 4. 1型糖尿病の予測 prediction of type 1 diabetes mellitus
- 5. 1型糖尿病の病因 pathogenesis of type 1 diabetes mellitus
English Journal
- Identification and characterization of calcium transporter gene family in finger millet in relation to grain calcium content.
- Singh UM1, Metwal M2, Singh M2, Taj G2, Kumar A3.
- Gene.Gene.2015 Jul 15;566(1):37-46. doi: 10.1016/j.gene.2015.04.021. Epub 2015 Apr 11.
- Calcium (Ca) is an essential mineral for proper growth and development of plants as well as animals. In plants including cereals, calcium is deposited in seed during its development which is mediated by specialized Ca transporters. Common cereal seeds contain very low amounts of Ca while the finger
- PMID 25869323
- Functional characterization of the organic cation transporters (OCTs) in human airway pulmonary epithelial cells.
- Ingoglia F1, Visigalli R1, Rotoli BM1, Barilli A1, Riccardi B2, Puccini P2, Dall'Asta V3.
- Biochimica et biophysica acta.Biochim Biophys Acta.2015 Jul;1848(7):1563-72. doi: 10.1016/j.bbamem.2015.04.001. Epub 2015 Apr 13.
- Organic cation transporters (OCT1-3) mediate the transport of organic cations including inhaled drugs across the cell membrane, although their role in lung epithelium hasn't been well understood yet. We address here the expression and functional activity of OCT1-3 in human airway epithelial cells A5
- PMID 25883089
- Steady-state pharmacokinetics of metformin is independent of the OCT1 genotype in healthy volunteers.
- Christensen MM1, Højlund K, Hother-Nielsen O, Stage TB, Damkier P, Beck-Nielsen H, Brøsen K.
- European journal of clinical pharmacology.Eur J Clin Pharmacol.2015 Jun;71(6):691-7. doi: 10.1007/s00228-015-1853-8. Epub 2015 May 5.
- PURPOSE: The aim of the study was to determine the steady-state pharmacokinetics of metformin in healthy volunteers with different numbers of reduced-function alleles in the organic cation transporter 1 gene (OCT1).METHODS: The study was conducted as part of a randomized cross-over trial. Thirty-fou
- PMID 25939711
Japanese Journal
- Evidence for organic cation transporter-mediated metformin transport and 5'-adenosine monophosphate-activated protein kinase activation in rat skeletal muscles.
- Oshima Rieko,Yamada Mayumi,Kurogi Eriko,Ogino Yohei,Serizawa Yasuhiro,Tsuda Satoshi,Ma Xiao,Egawa Tatsuro,Hayashi Tatsuya
- Metabolism 64(2), 296-304, 2015-02
- … We investigated whether metformin (MET) acts directly on skeletal muscle, is transported into skeletal muscle via organic cation transporters (OCTs), and activates AMPK. …
- NAID 120005540403
- Gene Ablation of Carnitine/Organic Cation Transporter 1 Reduces Gastrointestinal Absorption of 5-Aminosalicylate in Mice
- Shimizu Takuya,Kijima Ai,Masuo Yusuke [他],Ishimoto Takahiro,Sugiura Tomoko,Takahashi Saki,Nakamichi Noritaka,Kato Yukio
- Biological and Pharmaceutical Bulletin 38(5), 774-780, 2015
- … We hypothesized that the absorption of 5-ASA is mediated by the polyspecific carnitine/organic cation transporter (OCTN1/SLC22A4), based on the similarity of chemical structure between 5-ASA and other OCTN1 substrates. … Therefore, we examined the involvement of this transporter in the disposition of 5-ASA in vivo by using octn1 gene knockout (octn1−/−) mice. …
- NAID 130005068086
- 麻薬性鎮痛薬の中枢効果を制御する血液脳関門輸送機構
- 黄倉 崇,樋口 慧,出口 芳春
- 薬学雑誌. 乙号 135(5), 697-702, 2015
- … In vitro transport study using BBB model cells showed that oxycodone is efficiently transported by a proton-coupled organic cation antiporter. … Human BBB model cells also retain the proton-coupled organic cation antiporter. … These findings support the idea that proton-coupled organic cation antiporter-mediated transport of oxycodone at the BBB plays a role in determining the therapeutic efficacy of this opioid analgesic drug. …
- NAID 130005066918
Related Links
- Knowledge Center > Transporters > OCT1 OCT1 Related Products Related Services Interested in FDA or EMA Compliant Transporter Studies? OCT1 Transporter (Organic Cation Transporter 1 / SLC22A1) SLC22A1, more commonly ...
- 適用 (1.0-5.0μg/mL) 交差性 その他 薬物及びその代謝物の膜輸送に関与する薬物トランスポーターは、基質認識の多様性等から、さまざまなトランスポーターに分類されています。特に、有機アニオン、同カチオン、両性イオンの3 つの ...
Related Pictures
★リンクテーブル★
| リンク元 | 「カチオントランスポーター」「cation transport protein」「陽イオン輸送体」 |
| 拡張検索 | 「organic cation transporter 1」 |
| 関連記事 | 「transport」「transporter」「cation」 |
「カチオントランスポーター」
「cation transport protein」
- カチオントランス・ーター、カチオン輸送体、カチオン輸送タンパク質
「陽イオン輸送体」
「organic cation transporter 1」
有機カチオン輸送体1、有機カチオントランス・ーター1
- 関
- OCT1
「transport」
- n.
- v.
- 輸送する、運搬する、運ぶ
「transporter」
「cation」
- 関
- cationic
- 関
- See also specific cations