WordNet
- limit, block, or decrease the action or function of; "inhibit the action of the enzyme"; "inhibit the rate of a chemical reaction"
- control and refrain from showing; of emotions, desires, impulses, or behavior (同)bottle up, suppress
- limit the range or extent of; "Contact between the young was inhibited by strict social customs"
- a substance that retards or stops an activity
PrepTutorEJDIC
- 〈感情・欲望・行動・作用など〉‘を'抑制する / (…しないように)〈人〉‘を'抑制する,妨げる《+『名』+『from』+『名』(do『ing』)》
- 抑制する人(物) / 化学反応抑制剤
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/05/23 00:52:05」(JST)
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- 1. 頭頸部の扁平上皮癌化：分子学的および遺伝学的変化 head and neck squamous cell carcinogenesis molecular and genetic alterations
- 2. 成人におけるステロイド抵抗性およびステロイド依存性の潰瘍性大腸炎に対するアプローチ approach to adults with steroid refractory and steroid dependent ulcerative colitis
- 3. 関節リウマチの病因 pathogenesis of rheumatoid arthritis
- 4. 慢性閉塞性肺疾患（COPD）：危険因子およびリスク低減 chronic obstructive pulmonary disease risk factors and risk reduction
- 5. リウマチ性疾患におけるサイトカインネットワーク：治療の意味 cytokine networks in rheumatic diseases implications for therapy
English Journal
- Novel oxazolo-oxazole derivatives of FTY720 reduce endothelial cell permeability, immune cell chemotaxis and symptoms of experimental autoimmune encephalomyelitis in mice.
- Imeri F1, Fallegger D1, Zivkovic A2, Schwalm S3, Enzmann G4, Blankenbach K3, Meyer Zu Heringdorf D3, Homann T5, Kleuser B5, Pfeilschifter J3, Engelhardt B4, Stark H2, Huwiler A6.
- Neuropharmacology.Neuropharmacology.2014 Oct;85:314-27. doi: 10.1016/j.neuropharm.2014.05.012. Epub 2014 May 23.
- The immunomodulatory FTY720 (fingolimod) is presently approved for the treatment of relapsing-remitting multiple sclerosis. It is a prodrug that acts by modulating sphingosine 1-phosphate (S1P) receptor signaling. In this study, we have developed and characterized two novel oxazolo-oxazole derivativ
- PMID 24863045
- In Crohn's disease fibrosis-reduced expression of the miR-29 family enhances collagen expression in intestinal fibroblasts.
- Nijhuis A1, Biancheri P2, Lewis A1, Bishop CL3, Giuffrida P2, Chan C4, Feakins R5, Poulsom R1, Di Sabatino A6, Corazza GR6, MacDonald TT2, Lindsay JO1, Silver AR1.
- Clinical science (London, England : 1979).Clin Sci (Lond).2014 Sep;127(5):341-50. doi: 10.1042/CS20140048.
- Intestinal fibrosis with stricture formation is a complication of CD (Crohn's disease) that may mandate surgical resection. Accurate biomarkers that reflect the relative contribution of fibrosis to an individual stricture are an unmet need in managing patients with CD. The miRNA-29 (miR-29) family h
- PMID 24641356
- Effects of polycystin‑1 N‑terminal fragment fusion protein on the proliferation and apoptosis of rat mesangial cells.
- Guan T1, Gao Q1, Chen P1, Fu L2, Zhao H3, Zou Z2, Mei C2.
- Molecular medicine reports.Mol Med Rep.2014 Sep;10(3):1626-1634. doi: 10.3892/mmr.2014.2354. Epub 2014 Jun 26.
- Mesangial proliferative glomerulonephritis (MsPGN) is characterized by widespread mesangial cell proliferation and an accumulation of extracellular matrix (ECM) in the mesangial area. In a previous study we developed a polycystin‑1 N‑terminal fragment (PC‑1 NF) fusion protein that inhibits the
- PMID 24970599
Japanese Journal
- Yellow Wine Polyphenolic Compounds Inhibit Matrix Metalloproteinase-2, -9 Expression and Improve Atherosclerotic Plaque in LDL-Receptor-Knockout Mice
- Zhai Xiaoya,Chi Jufang,Tang Weiliang [他]
- Journal of pharmacological sciences 125(2), 132-141, 2014-06
- NAID 40020097585
- Proteolytic and Non-proteolytic Activation of Keratinocyte-Derived Latent TGF-β1 Induces Fibroblast Differentiation in a Wound-Healing Model Using Rat Skin
- Hata Shozaburo,Okamura Kazuhiko,Hatta Mitsutoki,Ishikawa Hiroyuki,Yamazaki Jun
- Journal of Pharmacological Sciences, 2014
- … α-SMA expression was inhibited by an anti-αv-integrin antibody and a matrix metalloproteinase (MMP) inhibitor, GM6001. …
- NAID 130003391483
- A Novel Role of Sympathetic Activity in Regulating Mitral Valve Prolapse
- Hu Xiang,Wang Hao-Zhe,Liu Jun,Chen An-Qin,Ye Xiao-Feng,Zhao Qiang
- Circulation Journal, 2014
- … In view of the extracellular matrix remodel, sympathetic effects presented catabolic metabolism displaying significantly increased expressions of total, secretory and active MMP-2 protein (matrix metalloproteinase-2), as well as MMP-9 protein. … Diminished MMP inhibitor expression, TIMP2, also could reflect this effect in the norepinephrine medium. …
- NAID 130003391112
Related Links
- A novel metalloproteinase inhibitor, analogs thereof, polynucleotides encoding the same, and methods of production, are disclosed. Pharmaceutical compositions and methods of treating disorders caused ... The present ...
- Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2 ...
Related Pictures
★リンクテーブル★
| リンク元 | 「メタロプロテアーゼ阻害剤」「メタロプロテアーゼ阻害薬」 |
| 関連記事 | 「inhibit」「inhibitor」「metalloproteinase」「metalloproteinases」 |
「メタロプロテアーゼ阻害剤」
「メタロプロテアーゼ阻害薬」
「inhibit」
- v.
- 抑制する、阻害する、阻止する
- 関
- abrogate、block、depress、depression、deter、inhibition、interdict、prevent、prevention、repress、repression、restrain、restraint、suppress、suppression
「inhibitor」
- n.