mannose-binding protein-associated serine protease

マンノース結合タンパク質関連セリンプロテアーゼ

関

MASP、MBP-associated serine protease

WordNet

1. having partial rights and privileges or subordinate status; "an associate member"; "an associate professor"
2. a person who joins with others in some activity or endeavor; "he had to consult his associate before continuing"
3. a person with subordinate membership in a society, institution, or commercial enterprise; "associates in the law firm bill at a lower rate than do partners"
4. any event that usually accompanies or is closely connected with another; "first was the lightning and then its thunderous associate"
5. make a logical or causal connection; "I cannot connect these two pieces of evidence in my mind"; "colligate these facts"; "I cannot relate these events at all" (同)tie_in, relate, link, colligate, link up, connect
6. executed with proper legal authority; "a binding contract"
7. the protective covering on the front, back, and spine of a book; "the book had a leather binding" (同)book binding, cover, back
8. strip sewn over or along an edge for reinforcement or decoration
9. the capacity to attract and hold something
10. any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
11. any enzyme that catalyzes the splitting of proteins into smaller peptide fractions and amino acids by a process known as proteolysis (同)peptidase, proteinase, proteolytic_enzyme
12. a sweetish crystalline amino acid involved in the synthesis by the body of cysteine

PrepTutorEJDIC

1. 〈人〉'を'(…の)『仲間に加える』,(…に)連合させる《+『名』〈人〉+『with』+『名』》 / (…と)…'を'結びつけて考える(起こす)《+『名』+『with』+『名』》 / (…と)『仲間になる』,交際する《+『with』+『名』》 / (…と)合体する,提携する《+『with』+『名』》 / 『仲間』,『同僚』;組合員 / 準会員 / 付属物;連想されるもの / 連合した;仲間の,同僚の / 補助の,準…
2. 義務的な,拘束力ある / 〈U〉しばること;〈C〉しばる物 / 〈C〉製本,装丁 / 〈U〉縁(‘ふち')取り材料
3. 蛋白(たんばく)質

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/02/26 22:23:52」(JST)

wiki en

[Wiki en表示]

Mannose-binding protein-associated serine protease are serine proteases involved in the complement system.

Types include:

• MASP1 (protein)
• MASP2 (protein)

See also

• mannan-binding lectin

UpToDate Contents

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• 1. マンノース結合レクチン欠損症 mannose binding lectin deficiency
• 2. マンノース結合レクチン mannose binding lectin
• 3. 補体系の概要および臨床的評価 overview and clinical assessment of the complement system
• 4. 補体系の遺伝性疾患 inherited disorders of the complement system
• 5. 補体系の制御因子および受容体 regulators and receptors of the complement system

English Journal

• The lectin complement pathway serine proteases (MASPs) represent a possible crossroad between the coagulation and complement systems in thromboinflammation.

• Kozarcanin H1, Lood C2, Munthe-Fog L3, Sandholm K4, Hamad OA1, Bengtsson AA2, Skjoedt MO3, Huber-Lang M5, Garred P3, Ekdahl KN1,4, Nilsson B1.
• Journal of thrombosis and haemostasis : JTH.J Thromb Haemost.2015 Nov 28. doi: 10.1111/jth.13208. [Epub ahead of print]
• BACKGROUND: The activated forms of the complement lectin pathway (LP) proteases MASP-1 and -2 are able to cleave the coagulation factors prothrombin, fibrinogen, factor XIII and TAFI in vitro. In vivo studies also show that MASP-1 is involved in thrombogenesis, OBJECTIVES: To clarify the not yet ide
• PMID 26614707

• Investigation of the mechanism of interaction between Mannose-binding lectin-associated serine protease-2 and complement C4.

• Drentin N1, Conroy P1, Gunzburg MJ1, Pike RN2, Wijeyewickrema LC3.
• Molecular immunology.Mol Immunol.2015 Oct;67(2 Pt B):287-93. doi: 10.1016/j.molimm.2015.06.011. Epub 2015 Jun 27.
• The interaction between mannose-binding lectin [MBL]-associated serine protease-2 (MASP-2) and its first substrate, C4 is crucial to the lectin pathway of complement, which is vital for innate host immunity, but also involved in a number of inflammatory diseases. Recent data suggests that two areas
• PMID 26130224

• Low MBL-associated serine protease 2 (MASP-2) levels correlate with urogenital schistosomiasis in Nigerian children.

• Ojurongbe O1,2, Antony JS1, Van Tong H1, Meyer CG1, Akindele AA2, Sina-Agbaje OR3, Kremsner PG1, Velavan TP1,4.
• Tropical medicine & international health : TM & IH.Trop Med Int Health.2015 Oct;20(10):1311-9. doi: 10.1111/tmi.12551. Epub 2015 Jun 25.
• OBJECTIVES: The human mannose-binding lectin (MBL) and ficolins (FCN) are involved in pathogen recognition in the first line of defence. They support activation of the complement lectin cascade in the presence of MBL-associated serine protease 2 (MASP-2), a protein that cleaves the C4 and C2 complem
• PMID 26046446

Japanese Journal

• Exon structure of the gene encoding the human mannose-binding protein-associated serine protease light chain: commparison with complement C1r and C1s genes

• ENDO Yuichi,SATO Tetsuo,MATSUSHITA Misao,FUJITA Teizo
• International immunology 8(9), 1355-1358, 1996
• NAID 10005213086

• α_2-macroglobulin binds to and inhibits mannose-binding protein-associated serine protease

• TERAI I.
• Int Immunol 7, 1579-1584, 1995
• NAID 30024444567

• α_2-Macroglobulin binds to and inhibits mannose-binding protein-associated serine protease

• TERAI Itaru,KOBAYASHI Kunihiko,MATSUSHITA Misao,FUJITA Teizo,MATSUNO Kazuhiko
• International immunology 7(10), 1579-1584, 1995
• NAID 10005206784

Related Links

• Mannose-binding lectin (MBL)-associated serine protease ...

1. J Immunol. 2008 May 1;180(9):6132-8. Mannose-binding lectin (MBL)-associated serine protease (MASP)-1 contributes to activation of the lectin complement pathway. Takahashi M(1), Iwaki D, Kanno K, Ishida Y, Xiong ...

• Crystal structure of the CUB1-EGF-CUB2 region of mannose ...

1. EMBO J. 2003 May 15;22(10):2348-59. Crystal structure of the CUB1-EGF-CUB2 region of mannose-binding protein associated serine protease-2. Feinberg H(1), Uitdehaag JC, Davies JM, Wallis R, Drickamer K, Weis ...

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★リンクテーブル★

リンク元	「MBP-associated serine protease」「マンノース結合タンパク質関連セリンプロテアーゼ」
関連記事	「associate」「binding」「binding protein」「serine protease」「associated」

「MBP-associated serine protease」

　　[★]

• (補体活性化酵素)マンノース結合タンパク質関連セリンプロテアーゼ、MBP関連セリンプロテアーゼ

関

mannose-binding protein-associated serine protease、MASP

「マンノース結合タンパク質関連セリンプロテアーゼ」

　　[★]

英

mannose-binding protein-associated serine protease、MBP-associated serine protease、MASP

関

MBP関連セリンプロテアーゼ

「associate」

　　[★]

• vt.

• 結合する、連合させる。連想によって結びつける。(人を)仲間/友達などとしての関係に置く。(化)会合させる

• vi.

• 仲間/友人などとして交際する(with)。一つにまとめる、連合する

• n.

• 仕事仲間、提携者、同僚。友人、朋友。準会員。従業員、社員
• 密接な蒸す偽付きのある物、付随する物、つきもの。準国家
• 連想によって心に浮かぶ言葉/思い、連想物

• adj.

• 仲間の、同僚の。製紙機械員に次ぐ資格の
• 付随する、連想される

関

accompany、association、associative、attach、bearing、bind、binding、bond、bonding、coassemble、colleague、combine、conjoin、conjugate、conjugation、conjunction、connect、connection、correlate、correlation、couple、dock、engage、engagement、federation、implication、join、joint、ligate、link、linkage、peer、pertinent、reference、relate、relation、relationship、relative、relevance、relevant、symphysial、union

　 　 　 　 　 　

「binding」

　　[★]

• n.

• 結合、バインディング

• adj.

• 結合性の

関

affinity、associate、bind、bond、bonding、combine、conjoin、conjugate、conjugation、conjunction、connect、connection、connective、connectivity、couple、dock、engage、engagement、join、ligate、linkage、symphysial、symphysic、union

　 　 　 　 　

「binding protein」

　　[★]

• 結合タンパク質、結合タンパク、結合蛋白質、結合蛋白

関

BP、carrier protein、transport protein

「serine protease」

　　[★]

セリンプロテアーゼ

関

Ser protease、serine endopeptidase、serine proteinase

「associated」

　　[★]

• adj.

• 随伴の、随伴性の

関

concomitant、erratic、erratically

associate