malignancy associated hypercalcemia

悪性腫瘍に伴う高カルシウム血症

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• 1. 悪性腫瘍の高カルシウム血症：発症機序hypercalcemia of malignancy mechanisms [show details]
  …tumors and hematologic malignancies. The most common cancers associated with hypercalcemia in the United States are breast, renal, and lung cancer and multiple myeloma . Malignancy is usually evident clinically …
• 2. 高カルシウム血症の治療treatment of hypercalcemia [show details]
  … both effective therapies for hypercalcemia and are considered treatments of last resort. Dialysis may be indicated in patients with severe malignancy-associated hypercalcemia and renal insufficiency or heart …
• 3. 高カルシウム血症への診断的アプローチdiagnostic approach to hypercalcemia [show details]
  … although they do occur and are more common in patients with malignancy-associated hypercalcemia. In almost all patients, hypercalcemia is due to an elevation in the physiologically important ionized …
• 4. 高カルシウム血症の原因etiology of hypercalcemia [show details]
  … nonparathyroid cancers that secreted PTH, not PTHrP, have been reported. Hypercalcemia of malignancy is reviewed in more detail elsewhere. Mild hypercalcemia occurs in up to 15… transient hypercalcemia that can occur after successful renal transplantation. Theophylline toxicity has been associated with mild hypercalcemia . As in hyperthyroidism, the hypercalcemia usually subsides…
• 5. 高カルシウム血症の臨床症状clinical manifestations of hypercalcemia [show details]
  … Hypercalcemia can be produced by a variety of disorders, but primary hyperparathyroidism and malignancy account for most cases . It may be associated with a spectrum of clinical manifestations , ranging …

English Journal

• Severe hypercalcaemia of primary hyperparathyroidism: Could giant adenoma be the real culprit rather than carcinoma?

• Gücek Haciyanli S, Acar N, Gür EÖ, Çelik SC, Karaıslı S, Dilek ON, Haciyanli M.
• Annals of the Royal College of Surgeons of England. 2020 Apr;()1-6.
• Hypercalcaemic crisis is a rare manifestation of hyperparathyroidism and occurs in 1.6-6% of patients with primary hyperparathyroidism (pHPT). Although such high serum calcium levels (>14mg/dl) are attributed to malignancy, it is also associated with benign disease of the parathyroid glands. The aim
• PMID 32233846

• Calcitriol Elevation Is Associated with a Higher Risk of Refractory Hypercalcemia of Malignancy in Solid Tumors.

• Chukir T, Liu Y, Hoffman K, Bilezikian JP, Farooki A.
• The Journal of clinical endocrinology and metabolism. 2020 Apr;105(4).
• Hypercalcemia of malignancy (HCM) is a common complication of advanced cancer. PTH-independent HCM may be mediated through different mechanisms: (1) humoral HCM, caused by the secretion of PTH-related peptide (PTHrP), (2) local osteolysis resulting from metastatic lesions, and (3) calcitriol-mediate
• PMID 31841590

• Risk Factors for Development of Hypocalcemia in Patients With Cancer Treated With Bone-Modifying Agents.

• White PS, Dennis M, Jones EA, Weinberg JM, Sarosiek S.
• Journal of the National Comprehensive Cancer Network : JNCCN. 2020 04;18(4)420-427.
• This retrospective analysis describes the prevalence of and risk factors associated with the development of hypocalcemia in patients with cancer receiving bone-modifying agents (BMAs) as supportive care. Patients with cancer treated with an intravenous or subcutaneous BMA, including pamidronate, zol
• PMID 32259788

Japanese Journal

• 二次性副甲状腺機能亢進症に好酸性細胞腺腫併発が疑われた甲状腺乳頭癌合併血液透析患者の1例

• 加藤 一彦,田尻 進,小池 健太郎,丸山 之雄,大城戸 一郎,横尾 隆,内山 威人,田尻 瑛子,菊地 亮,鳥海 弥寿雄,河内 瑠李,畑中 彩恵子,仲長 奈央子,亀島 佐保子
• 日本透析医学会雑誌 53(2), 85-91, 2020
• <p>症例は66歳, 男性. 糖尿病性腎症による慢性腎不全に対してX-9年より血液透析を開始, 徐々に副甲状腺ホルモンは上昇し, X年血液生化学検査にて血清カルシウムは10.4mg/dL, 副甲状腺ホルモンは568pg/mLと高値を示した. 頸部超音波検査では甲状腺右葉背側, 左葉背側および下極部に血流豊富な8～14mm大の低エコー腫瘤を認め, またMIBIシンチグラフィーでは異所性集 …
• NAID 130007803154

• Anaplastic large cell lymphoma, with 1,25(OH)_²D_³-mediated hypercalcemia: A case report

• Mitobe Masaki,Masuko Masayoshi,Miyoshi Hiroaki,Ohshima Koichi,Sone Hirohito,Takizawa Jun,Kawamoto Keisuke,Suzuki Takaharu,Kiryu Maiko,Nanba Ayako,Suwabe Tatsuya,Tanaka Tomoyuki,Fuse Kyoko,Shibasaki Yasuhiko
• Ｊｏｕｒｎａｌ　ｏｆ　Ｃｌｉｎｉｃａｌ　ａｎｄ　Ｅｘｐｅｒｉｍｅｎｔａｌ　Ｈｅｍａｔｏｐａｔｈｏｌｏｇｙ 59(1), 22-28, 2019
• … <p>Hypercalcemia due to malignant tumors including malignant lymphomas is relatively common. … Among cancer patients with hypercalcemia, humoral hypercalcemia of malignancy is the most common and accounts for about 80% of all cases with hypercalcemia. …
• NAID 130007626106

• カルボプラチン，パクリタキセル，ベバシズマブ併用療法が奏効したhumoral hypercalcemia of malignancy合併肺多形癌の1例

• 小川 尚彦,木村 英晴,谷村 航太,米田 太郎,曽根 崇,笠原 寿郎
• 肺癌 57(3), 221-225, 2017
• … <p><b>背景．</b>肺多形癌は稀な肺腫瘍であり，一般的に予後不良である．副甲状腺ホルモン関連蛋白（parathyroid hormone-related protein；PTHrP）の上昇に伴う高Ca血症（humoral hypercalcemia of malignancy；HHM）を合併した肺多形癌の報告は稀である．<b>症例．</b>59歳の現喫煙男性．右肩から背部にかけての疼痛を訴え受診した．胸部CTにて右上葉に胸壁に浸潤する11 cm大の腫瘤影と左副腎腫大を …
• NAID 130005708209

Related Links

• UpToDate

The most common cancers associated with hypercalcemia in the United States are breast, renal, and lung cancer and multiple myeloma []. Malignancy is usually evident clinically by the time it causes hypercalcemia, and patients

• Malignancy-associated hypercalcemia - Cancer Therapy Advisor

Malignancy-associated hypercalcemia carries a very poor prognosis with 30-day mortality approaching 50%. Potential survival benefits had been reported with bisphosphonate use in breast cancer and ...

• Hypercalcemia of Malignancy: An Update on Pathogenesis ...

Hypercalcemia of malignancy is a common finding typically found in patients with advanced stage cancers. We aimed to provide an updated review on the etiology, pathogenesis, clinical presentation, and management of malignancy-related hypercalcemia. We ...

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★リンクテーブル★

リンク元	「悪性腫瘍に伴う高カルシウム血症」「MAH」
関連記事	「associate」「malignancy」「associated」「hypercalcemia」

「悪性腫瘍に伴う高カルシウム血症」

　　[★]

英

malignancy associated hypercalcemia, MAH, MAHC

同

悪性腫瘍随伴性高カルシウム血症

関

腫瘍随伴症候群

症状

高カルシウム血症に基づく症状

「MAH」

　　[★] malignancy associated hypercalcemia

「associate」

　　[★]

• vt.

• 結合する、連合させる。連想によって結びつける。(人を)仲間/友達などとしての関係に置く。(化)会合させる

• vi.

• 仲間/友人などとして交際する(with)。一つにまとめる、連合する

• n.

• 仕事仲間、提携者、同僚。友人、朋友。準会員。従業員、社員
• 密接な蒸す偽付きのある物、付随する物、つきもの。準国家
• 連想によって心に浮かぶ言葉/思い、連想物

• adj.

• 仲間の、同僚の。製紙機械員に次ぐ資格の
• 付随する、連想される

関

accompany、association、associative、attach、bearing、bind、binding、bond、bonding、coassemble、colleague、combine、conjoin、conjugate、conjugation、conjunction、connect、connection、correlate、correlation、couple、dock、engage、engagement、federation、implication、join、joint、ligate、link、linkage、peer、pertinent、reference、relate、relation、relationship、relative、relevance、relevant、symphysial、union

　 　 　 　 　 　

「malignancy」

　　[★]

• n.

• 強い悪意、敵意、激しい憎しみ。有害、有害なもの。(医)(病気の)悪性/悪性度。(医)悪性腫瘍

関

cancer

　 　

「associated」

　　[★]

• adj.

• 随伴の、随伴性の

関

concomitant、erratic、erratically

associate

「hypercalcemia」

　　[★] 高カルシウム血症