- 肝細胞内に多量の中性脂肪が蓄積した状態
WordNet
- pursue a positive and satisfying existence; "You must accept yourself and others if you really want to live"
- actually being performed at the time of hearing or viewing; "a live television program"; "brought to you live from Lincoln Center"; "live entertainment involves performers actually in the physical presence of a live audience" (同)unrecorded
- abounding with life and energy; "the club members are a really live bunch"
- charged with an explosive; "live ammunition"; "a live bomb"
- exerting force or containing energy; "live coals"; "tossed a live cigarette out the window"; "got a shock from a live wire"; "live ore is unmined ore"; "a live bomb"; "a live ball is one in play"
- highly reverberant; "a live concert hall"
- in current use or ready for use; "live copy is ready to be set in type or already set but not yet proofread"
- lead a certain kind of life; live in a certain style; "we had to live frugally after the war"
- not recorded; "the opera was broadcast live"
- of current relevance; "a live issue"; "still a live option"
- a person who has a special life style; "a high liver"
- large and complicated reddish-brown glandular organ located in the upper right portion of the abdominal cavity; secretes bile and functions in metabolism of protein and carbohydrate and fat; synthesizes substances involved in the clotting of the blood; sy
- liver of an animal used as meat
- someone who lives in a place; "a liver in cities"
PrepTutorEJDIC
- 『生きている』,生命がある / 《副詞[句]を伴って》〈人などが〉『生き続ける』 / 〈物事が〉長く続く,存続する / 《場所を表す副詞[句]を伴って》〈人などが〉『住む』,居住する / 《副詞[句]を伴って》『生活する』,暮らす / 生人を楽しむ,おもしろく桟らす / 《a+形容詞癌lifeを目的語にして》〈…を生活〉‘を'する / 〈思想など〉‘を'実銭する
- 《名詞の前にのみ用いて》『生きている』 / 『活気のある』 / (問題などが)当面の / 燃えている / (弾丸などが)まだ爆発してない,未発の / まだ動いている(働いている),有効な / 電流が通じている / (放走が)生の,実況の
- (ある態度で)生活する人;居住者
- 〈C〉『肝臓』 / 〈U〉(食用にする)動物の肝臓,レバー
UpToDate Contents
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- 1. 成人における非アルコール性脂肪性肝疾患（NAFLD）の疫学、臨床的特徴、および診断 epidemiology clinical features and diagnosis of nonalcoholic fatty liver disease in adults
- 2. 成人における非アルコール性脂肪肝疾患の自然経過およびマネージメント natural history and management of nonalcoholic fatty liver disease in adults
- 3. アルコール性脂肪性肝炎およびアルコール性肝硬変の臨床症状および診断 clinical manifestations and diagnosis of alcoholic fatty liver disease and alcoholic cirrhosis
- 4. 嚢胞性線維症：肝胆道系疾患 cystic fibrosis hepatobiliary disease
- 5. 肝酵素および肝機能検査値の異常が認められた患者に対するアプローチ approach to the patient with abnormal liver biochemical and function tests
English Journal
- Sardine (Sardina pilchardus) lipid composition: Does it change after one year in captivity?
- Bandarra NM1, Marçalo A2, Cordeiro AR3, Pousão-Ferreira P2.
- Food chemistry.Food Chem.2018 Apr 1;244:408-413. doi: 10.1016/j.foodchem.2017.09.147. Epub 2017 Sep 30.
- PMID 29120801
- Novel circulating biomarkers for non-alcoholic fatty liver disease: A systematic review.
- Sahebkar A1,2, Sancho E3, Abelló D3, Camps J3, Joven J3.
- Journal of cellular physiology.J Cell Physiol.2018 Feb;233(2):849-855. doi: 10.1002/jcp.25779. Epub 2017 Mar 28.
- PMID 28063221
- Improvement of feed pellet characteristics by dietary pre-gelatinized starch and their subsequent effects on growth and physiology in tilapia.
- Kanmani N1, Romano N2, Ebrahimi M3, Nurul Amin SM1, Kamarudin MS1, Karami A4, Kumar V5.
- Food chemistry.Food Chem.2018 Jan 15;239:1037-1046. doi: 10.1016/j.foodchem.2017.07.061. Epub 2017 Jul 13.
- PMID 28873520
Japanese Journal
- Glucoraphanin Ameliorates Obesity and Insulin Resistance Through Adipose Tissue Browning and Reduction of Metabolic Endotoxemia in Mice
- Diabetes 66(5), 1222-1236, 2017-05
- NAID 120006226752
- Toyocamycin attenuates free fatty acid-induced hepatic steatosis and apoptosis in cultured hepatocytes and ameliorates nonalcoholic fatty liver disease in mice
- PLOS ONE 12(3), e0170591, 2017-03-09
- NAID 120006221058
- Relevance of FXR-p62/SQSTM1 pathway for survival and protection of mouse hepatocytes and liver, especially with steatosis
- BMC gastroenterology 17(1), 9, 2017-01-13
- NAID 120005981455
Related Links
- Fatty liver, or steatosis, is a broad term that describes the buildup of fats in the liver. Having fat in your liver is normal, but if more than 5 to 10 percent is fat, then it’s called fatty liver disease.
- Continued Symptoms of Fatty Liver Disease You might have fatty liver disease and not realize it. There are often no symptoms at first. As time goes on, often years or even decades, you can get problems like: Feeling ...
Related Pictures
★リンクテーブル★
| リンク元 | 「脂肪肝」 |
| 関連記事 | 「live」「liver」 |
「脂肪肝」
概念
- 脂肪滴を含んだ肝細胞が、小葉の1/3以上に及んだ病態で、肝臓全体としては脂肪が10%以上蓄積する(正常2-4%)。
- おそらく、脂肪肝(＝？非アルコール性脂肪性肝疾患 nonalcoholic fatty liver disease NAFLD)は高位の概念で、この中に非アルコール性脂肪肝炎 NASHが含まれ、NASHはNASLDの極端な病態(障害が高度という意味か)である。(参考1)
病態生理
- see BPT.654 uptodate.2
原因
- YN.B-36改変 uptodate.1
- 栄養不良状態：クワシオルコル
- 過剰栄養摂取・状態
- 内分泌・代謝異常
- 甲状腺機能亢進症 ← 高トリグリセリド血症となるため(uptodate.1)
- クッシング症候群
- 薬剤性
- 妊娠：急性妊娠脂肪肝
- その他
検査
- 血液検査
- AST・ALT：正常かやや上昇(ALT優位) (YN.B-36) ⇔ アルコール性脂肪肝ではAST優位
- 思うに、小葉辺縁(門脈域)にはALTが多いが、脂肪滴を蓄えた肝細胞はこの領域に多いのでは？だとすれば、lipid peroxidation productによる肝障害によりALTがleakしてALT優位となる説明がつくのだが。どうなの？
CT
- 脂肪肝：単純CTで肝実質のCT値が脾臓よりも低くなる。正常な肝臓は脈管より高CT値を示すが、脂肪肝の場合はより低CT値を示すようになる
- 肝臓CT値低下の鑑別診断：肝炎に伴う浮腫、肝臓の線維化、腫瘍浸潤(悪性リンパ腫、びまん性肝細胞癌)、アミロイドーシス
==参考==liver disease - wiki en
uptodate
「live」
- [liv]
- vt.
- vi.
- [laiv]
- adj.
- 同
- LAIV