同: LFA-1

WordNet

having partial rights and privileges or subordinate status; "an associate member"; "an associate professor"
a person who joins with others in some activity or endeavor; "he had to consult his associate before continuing"
a person with subordinate membership in a society, institution, or commercial enterprise; "associates in the law firm bill at a lower rate than do partners"
any event that usually accompanies or is closely connected with another; "first was the lightning and then its thunderous associate"
make a logical or causal connection; "I cannot connect these two pieces of evidence in my mind"; "colligate these facts"; "I cannot relate these events at all" (同)tie_in, relate, link, colligate, link up, connect
perform as expected when applied; "The washing machine wont go unless its plugged in"; "Does this old car still run well?"; "This old radio doesnt work anymore" (同)work, operate, go, run
(mathematics) a mathematical relation such that each element of a given set (the domain of the function) is associated with an element of another set (the range of the function) (同)mathematical function, single-valued function, map, mapping
a relation such that one thing is dependent on another; "height is a function of age"; "price is a function of supply and demand"
the actions and activities assigned to or required or expected of a person or group; "the function of a teacher"; "the government must do its part"; "play its role" (同)office, part, role
what something is used for; "the function of an auger is to bore holes"; "ballet is beautiful but what use is it?" (同)purpose, role, use
a formal or official social gathering or ceremony; "it was a black-tie function"
any substance (as a toxin or enzyme) that stimulates an immune response in the body (especially the production of antibodies)
blood cells that engulf and digest bacteria and fungi; an important part of the bodys defense system (同)leucocyte, white_blood_cell, white_cell, white blood corpuscle, white_corpuscle, WBC
performing or able to perform its regular function; "a functioning flashlight"

PrepTutorEJDIC

〈人〉'を'(…の)『仲間に加える』,(…に)連合させる《+『名』〈人〉+『with』+『名』》 / (…と)…'を'結びつけて考える(起こす)《+『名』+『with』+『名』》 / (…と)『仲間になる』,交際する《+『with』+『名』》 / (…と)合体する,提携する《+『with』+『名』》 / 『仲間』,『同僚』;組合員 / 準会員 / 付属物;連想されるもの / 連合した;仲間の,同僚の / 補助の,準…
(人・物の果たすべき)『働き』,機能,役目;《しばしば複数形で》職務 / (公式の)儀式,《話》大きな催し(集まり),式典 / (数学で)関数 / 〈機械などが〉『機能を果たす』,動く / (…の)役目をする,代用となる《+『as』+『名』》
抗原(生物の体内にはいって免疫体を作る物質)

UpToDate Contents

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1. 移植免疫 transplantation immunobiology
2. 炎症の病因における白血球内皮細胞接着 leukocyte endothelial adhesion in the pathogenesis of inflammation
3. 臨床的腎移植における研究中の免疫抑制剤およびそのアプローチ investigational immunosuppressive drugs and approaches in clinical kidney transplantation
4. 胎児および新生児における免疫細胞の発達 the development of immune cells in the fetus and neonate
5. 自然免疫系の概要 an overview of the innate immune system

English Journal

DNA-based nanoparticle tension sensors reveal that T-cell receptors transmit defined pN forces to their antigens for enhanced fidelity.

Liu Y1, Blanchfield L2, Ma VP1, Andargachew R2, Galior K1, Liu Z1, Evavold B2, Salaita K3.
Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2016 May 17;113(20):5610-5. doi: 10.1073/pnas.1600163113. Epub 2016 May 2.
T cells are triggered when the T-cell receptor (TCR) encounters its antigenic ligand, the peptide-major histocompatibility complex (pMHC), on the surface of antigen presenting cells (APCs). Because T cells are highly migratory and antigen recognition occurs at an intermembrane junction where the T c
PMID 27140637

Anti-Leukocyte Function-Associated Antigen 1 Therapy in a Nonhuman Primate Renal Transplant Model of Costimulation Blockade-Resistant Rejection.

Anderson DJ1, Lo DJ1, Leopardi F2, Song M2, Turgeon NA1, Strobert EA1, Jenkins JB1, Wang R3, Reimann KA3, Larsen CP1, Kirk AD1,2.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.Am J Transplant.2016 May;16(5):1456-64. doi: 10.1111/ajt.13628. Epub 2016 Jan 14.
Costimulation blockade with the fusion protein belatacept provides a desirable side effect profile and improvement in renal function compared with calcineurin inhibition in renal transplantation. This comes at the cost of increased rates of early acute rejection. Blockade of the integrin molecule le
PMID 26602755

Lung ICAM-1 and ICAM-2 support spontaneous intravascular effector lymphocyte entrapment but are not required for neutrophil entrapment or emigration inside endotoxin-inflamed lungs.

Petrovich E1, Feigelson SW1, Stoler-Barak L1, Hatzav M1, Solomon A1, Bar-Shai A1, Ilan N2, Li JP3, Engelhardt B4, Vlodavsky I2, Alon R5.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.FASEB J.2016 May;30(5):1767-78. doi: 10.1096/fj.201500046. Epub 2016 Jan 28.
The pulmonary vasculature constitutively expresses the integrin lymphocyte function-associated antigen-1 ligands intercellular adhesion molecule (ICAM)-1 and -2. In this study, effector T cells were temporarily entrapped by the lung vasculature on their way to inflamed lymph nodes, and this entrapme
PMID 26823454

Japanese Journal

3) 血管内皮から観た妊娠高血圧症候群の病態とその発症予知(シンポジウム2:周産期「妊娠高血圧症候群の基礎と臨床-予防・治療の新戦略に向けて」,第65回日本産科婦人科学会・学術講演会)

松原圭一
日本産科婦人科學會雜誌 65(11), 2591-2603, 2013-11-01
… The failure harms the vasodilatory function of vascular endothelium and the placental vasculogenesis to keep the blood circulation increased during pregnancy. … As a result, serum factors derived from PIH patients activated the endothelial function through the increase of Ca^<++> … Adhesion (rolling-adhesion) between leukocyte and endothelium is an important process for the beginning of inflammation and the expression of adhesion molecules is important on the cells. …
NAID 110009674983

3) 血管内皮から観た妊娠高血圧症候群の病態とその発症予知(シンポジウム2:周産期「妊娠高血圧症候群の基礎と臨床-予防・治療の新戦略に向けて」,第65回日本産科婦人科学会・学術講演会)

松原圭一
日本産科婦人科學會雜誌 65(11), 2591-2603, 2013-11-01
… The failure harms the vasodilatory function of vascular endothelium and the placental vasculogenesis to keep the blood circulation increased during pregnancy. … As a result, serum factors derived from PIH patients activated the endothelial function through the increase of Ca^<++> … Adhesion (rolling-adhesion) between leukocyte and endothelium is an important process for the beginning of inflammation and the expression of adhesion molecules is important on the cells. …
NAID 110009661871

CD11aモノクローナル抗体(mNI-58A)のヒトNK様細胞株(KHYG-1)に対する細胞間凝集の誘導とインターフェロンγの産生増強

池脇信直,玉内秀一
九州保健福祉大学研究紀要 10, 217-227, 2009-03
我々が開発したCD11a(LFA-1α)モノクローナル抗体(mNI-58A)のヒトNK様細胞株(KHYG-1)に与える影響を検討したところ、mNI-58A抗体はKHYG-1細胞に対して細胞間凝集を特異的に誘導した。この細胞間凝集反応は、conventional protein kinase C (cPKC)抑制剤であるGo6976とnovel protein kinase C (nPKC)抑制剤で …
NAID 110007616436

「LFA-1」

　　[★]

関: lymphocyte function-associated antigen-1, leukocyte function-associated antigen 1
同: リンパ球機能関連抗原1
関: リンパ球機能関連抗原 LFA、インテグリン

同: CDlla

first aid step1 2006 p.190

臨床関連

白血球粘着不全症 leukocyte adhesion deficiency

「associate」

　　[★]

vt.

結合する、連合させる。連想によって結びつける。(人を)仲間/友達などとしての関係に置く。(化)会合させる

vi.

仲間/友人などとして交際する(with)。一つにまとめる、連合する

n.

仕事仲間、提携者、同僚。友人、朋友。準会員。従業員、社員
密接な蒸す偽付きのある物、付随する物、つきもの。準国家
連想によって心に浮かぶ言葉/思い、連想物

adj.

仲間の、同僚の。製紙機械員に次ぐ資格の
付随する、連想される

関: accompany、association、associative、attach、bearing、bind、binding、bond、bonding、coassemble、colleague、combine、conjoin、conjugate、conjugation、conjunction、connect、connection、correlate、correlation、couple、dock、engage、engagement、federation、implication、join、joint、ligate、link、linkage、peer、pertinent、reference、relate、relation、relationship、relative、relevance、relevant、symphysial、union

「function」

　　[★]

n.

機能、(数学)関数、(化学)官能基

survival as a function of HbA1c in people with type 2 diabetes HbA1cの機能を考慮（指標に）した2型糖尿病の患者の生存（予後）

Figure 2A shows survival as a function of device removal during index hpspitalization, censored at 1 year or date of last contact. (Figure2Aはは最初の入院中における心臓デバイス除去に関する生存曲線で退院後1年もしくは最後の接触で打ち切っている)