WordNet
- be a contributing factor; "make things factor into a companys profitability"
- any of the numbers (or symbols) that form a product when multiplied together
- an independent variable in statistics
- anything that contributes causally to a result; "a number of factors determined the outcome"
- consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
- resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
- an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"
- a concept whose truth can be proved; "scientific hypotheses are not facts"
- a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"
- a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"
- situated within or belonging solely to the organ or body part on which it acts; "intrinsic muscles"
- belonging to a thing by its very nature; "form was treated as something intrinsic, as the very essence of the thing"- John Dewey (同)intrinsical
- any of a large variety of proteins normally present in the body or produced in response to an antigen which it neutralizes, thus producing an immune response
PrepTutorEJDIC
- (…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize
- 〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行
- (価値・質などが)本質的な,本来備わった
- 抗体,免疫体,抗毒素
UpToDate Contents
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English Journal
- Regulation of autoantibody activity by the IL-23-TH17 axis determines the onset of autoimmune disease.
- Pfeifle R1,2, Rothe T1,2, Ipseiz N1,2, Scherer HU3, Culemann S1,2, Harre U1, Ackermann JA1,2, Seefried M2,4, Kleyer A1, Uderhardt S1,2, Haugg B1,2, Hueber AJ1, Daum P2,5, Heidkamp GF6, Ge C7, Böhm S4, Lux A4, Schuh W2,5, Magorivska I1, Nandakumar KS7, Lönnblom E7, Becker C8, Dudziak D6, Wuhrer M9, Rombouts Y3,9,10, Koeleman CA9, Toes R3, Winkler TH2,4, Holmdahl R7, Herrmann M1, Blüml S11, Nimmerjahn F4, Schett G1, Krönke G1,2.
- Nature immunology.Nat Immunol.2016 Nov 7. doi: 10.1038/ni.3579. [Epub ahead of print]
- The checkpoints and mechanisms that contribute to autoantibody-driven disease are as yet incompletely understood. Here we identified the axis of interleukin 23 (IL-23) and the TH17 subset of helper T cells as a decisive factor that controlled the intrinsic inflammatory activity of autoantibodies and
- PMID 27820809
- Coagulation Factor XI vaccination: an alternative strategy to prevent thrombosis.
- Zhong C1, Zhang L1, Chen L1, Deng L2, Li R3,4.
- Journal of thrombosis and haemostasis : JTH.J Thromb Haemost.2016 Nov 4. doi: 10.1111/jth.13561. [Epub ahead of print]
- BACKGROUND: Coagulation Factor XI (FXI) serves as a signal amplifier in the intrinsic coagulation pathway. Blockade of FXI by monoclonal antibodies or small molecule inhibitors inhibits thrombosis without causing severe bleeding, which is an inherent risk of currently available antithrombotic agents
- PMID 27813324
- FoxO3a confers cetuximab resistance in RAS wild-type metastatic colorectal cancer through c-Myc.
- Yu Y1, Guo M1, Wei Y2, Yu S1, Li H1, Wang Y1, Xu X1, Cui Y1, Tian J1, Liang L1, Peng K1, Liu T1.
- Oncotarget.Oncotarget.2016 Nov 4. doi: 10.18632/oncotarget.13105. [Epub ahead of print]
- Resistance to epidermal growth factor receptor (EGFR) targeted monoclonal antibody therapy represents a clinical challenge in patients suffered from RAS wild-type (WT) metastatic colorectal cancer (mCRC). However, the molecular mechanisms and key factors conferring this resistance are largely unknow
- PMID 27825133
Japanese Journal
- Introducing Site-Specific Glycosylation Using Protein Engineering Techniques Reduces the Immunogenicity of β-Lactoglobulin
- TATSUMI Yoshiyuki,SASAHARA Yoshimasa,KOHYAMA Noriki [他],AYANO Satomi,ENDO Michio,YOSHIDA Tadashi,YAMADA Kiyoshi,TOTSUKA Mamoru,HATTORI Makoto
- Bioscience, biotechnology, and biochemistry 76(3), 478-485, 2012-03-23
- … by fusion of the cDNA to the sequence coding for the α-factor signal peptide from <I>Saccharomyces cerevisiae</I>. … Structural analyses by intrinsic fluorescence, CD spectra, and ELISA with monoclonal antibodies indicated that the surface structure was slightly changed by using protein engineering techniques, but that the site-specifically glycosylated BLGs were covered by high-mannose chains without substantial disruption of wt conformation. …
- NAID 10030750451
- 抗内因子抗体 (広範囲 血液・尿化学検査 免疫学的検査(第7版・3)その数値をどう読むか) -- (免疫学的検査 自己抗体)
- 酸化修飾低密度リポタンパク質の生物活性とその活性抑制因子としてのAsp-hemolysinに関する分子生物学的研究
- 熊谷 健
- 藥學雜誌 126(10), 955-964, 2006-10-01
- … This study was undertaken to clarify the biological activity of OxLDL and the potentially of Asphemolysin as a regulation factor to atherogenic effect by OxLDL. … OxLDL caused prolongation of activated partial thromboplastin time (APTT) as a parameter of the intrinsic pathway of blood coagulation in a dose- and oxidation time-dependent manner. … In addition, OxLDL significantly inhibited blood coagulation factor VIII, IX, and XI activity. …
- NAID 110004811919
Related Links
- An intrinsic factor antibody (IF antibody) test may be used to help determine the cause of a vitamin B12 deficiency and to confirm a diagnosis of pernicious anemia. ... The results of intrinsic factor antibody (IF antibody) tests are often ...
- Intrinsic factor antibodies are proteins produced by the immune system that are associated with pernicious anemia. This test detects intrinsic factor antibody (IF antibody) circulating in blood. Intrinsic factor is a protein produced by a ...
Related Pictures
![](http://msp.c.yimg.jp/image?q=tbn:ANd9GcR32KtBMDI7cvC1ac-3DsC9mX-32vBSbLbRfcmmd_egdyoJkIMiWsadwg:http://a.abcam.com/ps/datasheet/images/91/ab91322/Intrinsic-Factor-Primary-antibodies-ab91322-2.jpg)
![](http://msp.c.yimg.jp/image?q=tbn:ANd9GcQJpoXySHDaC9aoYIYazotwDTE9gwqr1lpT6m8zVTnq498HWILRSFkEIJY:http://annals.org/data/Journals/AIM/19399/AIME196705010-00033.pdf.png)
![](http://msp.c.yimg.jp/image?q=tbn:ANd9GcSJYNY8JVzoviAU9PTfOecdCLU_aC7kjbkBNJIgJhbGc6bq1IOG8ffKlQ:http://www.drugs.com/health-guide/images/202795.jpg)
![](http://msp.c.yimg.jp/image?q=tbn:ANd9GcRT8s_3FhRNwhnFTj3rCZnzPTBYhjC9S_982JNd5obKj7dj3CorpHf50Pc:http://www.antibodies-online.com/media/138/images/anti-Cubilin%2BIntrinsic%2BFactor-Cobalamin%2BReceptor%2BCUBN%2Bantibody_scale_550x650_KR065.jpg)
![](http://msp.c.yimg.jp/image?q=tbn:ANd9GcTusK5ZP-czwZgfUVhhaYCrHHWX5SO4qErM0OPMPba0i03eeUUD88FkjA:http://www.abcam.co.jp/ps/datasheet/images/102/ab102049/Intrinsic-Factor-Primary-antibodies-ab102049-2.jpg)
★リンクテーブル★
[★]
- 英
- intrinsic factor antibody
[★]
- 関
- endemic、endogeneous、endogenous、endogenously、inherent、inherently、intrinsically、proper
[★]
- 関
- actual、actually、in fact、in practice、indeed、practically
[★]
- 関
- element、elementary、factorial、parameter