intracellular signal transduction mechanism

• 細胞内シグナル伝達機構、細胞内情報伝達機構

WordNet

1. place signs, as along a road; "sign an intersection"; "This road has been signed"
2. (medicine) any objective evidence of the presence of a disorder or disease; "there were no signs of asphyxiation"
3. a perceptible indication of something not immediately apparent (as a visible clue that something has happened); "he showed signs of strain"; "they welcomed the signs of spring" (同)mark
4. a character indicating a relation between quantities; "dont forget the minus sign"
5. a fundamental linguistic unit linking a signifier to that which is signified; "The bond between the signifier and the signified is arbitrary"--de Saussure
6. a gesture that is part of a sign language
7. a public display of a message; "he posted signs in all the shop windows"
8. engage by written agreement; "They signed two new pitchers for the next season" (同)contract, sign on, sign_up
9. approve and express assent, responsibility, or obligation; "All parties ratified the peace treaty"; "Have you signed your contract yet?" (同)ratify
10. communicate silently and non-verbally by signals or signs; "He signed his disapproval with a dismissive hand gesture"; "The diner signaled the waiters to bring the menu" (同)signal, signalize, signalise
11. mark with ones signature; write ones name (on); "She signed the letter and sent it off"; "Please sign here" (同)subscribe
12. be engaged by a written agreement; "He signed to play the casino on Dec. 18"; "The soprano signed to sing the new opera"
13. communicate in sign language; "I dont know how to sign, so I could not communicate with my deaf cousin"
14. the atomic process that occurs during a chemical reaction; "he determined unique mechanisms for the photochemical reactions" (同)chemical mechanism
15. the technical aspects of doing something; "a mechanism of social control"; "mechanisms of communication"; "the mechanics of prose style" (同)mechanics
16. device consisting of a piece of machinery; has moving parts that perform some function
17. (philosophy) the philosophical theory that all phenomena can be explained in terms of physical or biological causes
18. a natural object resembling a machine in structure or function; "the mechanism of the ear"; "the mechanism of infection"
19. notably out of the ordinary; "the year saw one signal triumph for the Labour party"
20. an electric quantity (voltage or current or field strength) whose modulation represents coded information about the source from which it comes
21. any nonverbal action or gesture that encodes a message; "signals from the boat suddenly stopped" (同)signaling, sign
22. any incitement to action; "he awaited the signal to start"; "the victory was a signal for wild celebration"
23. (genetics) the process of transfering genetic material from one cell to another by a plasmid or bacteriophage
24. the process whereby a transducer accepts energy in one form and gives back related energy in a different form; "the transduction of acoustic waves into voltages by a microphone"
25. located or occurring within a cell or cells; "intracellular fluid"

PrepTutorEJDIC

1. (ある事実・状態・感情などの)『表れ』,印,気配,徴侯(indication);(…の)こん跡,計跡《+『of』+『名』》・『身ぶり』,手まね,合図 / 『標識』,看板 / (数学・音楽などの)記号 / (…の)『象徴』,シンボル(symbol)《+『of』+『名』》・《文》(…の)『前兆』,きざし《+『of』+『名』》・宮(きゅう)(黄道12区分の一つ) ・〈手紙・書類・作品など〉‘に'『署名する』・(…に)〈名前など〉‘を'書く《+『名』+『on』(『to』)+『名』》 / …‘を'雇う契約に署名する・…‘を'合図する,知らせる;…に合図する・署名する・契約書に署名して雇われる
2. 〈C〉機械;(部分的な)機械装置 / 〈C〉(機械装置に似た)機構 / 〈C〉(物事が行われる)仕組み,方法 / 〈U〉機械論
3. (警告・指示・情報などを伝える)『信号』,合図 / (…の)きっかけ,動機,導火線《+『for』+『名』》 / 〈人・車など〉‘に'『合図する』,信号を送る / …‘を'『合図』(信号)『で知らせる』 / 『合図する』,信号する / 合図の,信号の / めざましい,顕著な

UpToDate Contents

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English Journal

• Phospholipase C Epsilon (PLCε) Induced TRPC6 Activation: A Common but Redundant Mechanism in Primary Podocytes.

• Kalwa H1, Storch U, Demleitner J, Fiedler S, Mayer T, Kannler M, Fahlbusch M, Barth H, Smrcka A, Hildebrandt F, Gudermann T, Dietrich A.
• Journal of cellular physiology.J Cell Physiol.2015 Jun;230(6):1389-99. doi: 10.1002/jcp.24883.
• In eukaryotic cells, activation of phospholipase C (PLC)-coupled membrane receptors by hormones leads to an increase in the intracellular Ca(2+) concentration [Ca(2+) ]i . Catalytic activity of PLCs results in the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate inositol 1,4,5-trispho
• PMID 25521631

• Hydroxysafflor yellow A inhibits angiogenesis of hepatocellular carcinoma via blocking ERK/MAPK and NF-κB signaling pathway in H22 tumor-bearing mice.

• Yang F1, Li J2, Zhu J3, Wang D2, Chen S4, Bai X5.
• European journal of pharmacology.Eur J Pharmacol.2015 May 5;754:105-14. doi: 10.1016/j.ejphar.2015.02.015. Epub 2015 Feb 24.
• Hydroxysafflor yellow A (HSYA), a flavonoid derived and isolated from traditional Chinese medicine Carthamus tinctorius L., possesses anti-tumor activity. However, its effects on hepatocellular carcinoma (HCC) have not been investigated. The proliferation and metastasis of HCC are dependent on angio
• PMID 25720342

• "Nuclear FGF receptor-1 and CREB binding protein: an integrative signaling module".

• Stachowiak MK1, Birkaya B, Aletta JM, Narla ST, Benson CA, Decker B, Stachowiak EK.
• Journal of cellular physiology.J Cell Physiol.2015 May;230(5):989-1002. doi: 10.1002/jcp.24879.
• In this review we summarize the current understanding of a novel integrative function of Fibroblast Growth Factor Receptor-1 (FGFR1) and its partner CREB Binding Protein (CBP) acting as a nuclear regulatory complex. Nuclear FGFR1 and CBP interact with and regulate numerous genes on various chromosom
• PMID 25503065

Japanese Journal

• 〈Original Papers〉哺乳動物初期胚におけるタンパク質分解機構の機能解明に向けた研究の現状と今後の展望

• 樋口 智香,清水 なつみ,天野 朋子,松本 和也
• Memoirs of the Faculty of Biology-Oriented Science and Technology of Kinki University 31, 59-65, 2013-03
• … Autophagy pathway has various biological effects, such as adaptive responses to starvation and quality control of intracellular proteins, UPS degrades selective proteins in eukaryotic cells, and regulates basic cell pathways such as cell cycle, signal transduction, cell death and development. …
• NAID 120005260079

• Signal transduction mechanism for potentiation by α1- and β2-adrenoceptor agonists of L-ascorbic acid-induced DNA synthesis and proliferation in primary cultures of adult rat hepatocytes

• 茂木 肇,木村 光利,須永 克佳,津田 整,荻原 政彦
• European Journal of Pharmacology 700(1-3), 2-12, 2013-01
• … Then intracellular signal transduction mechanisms for the effects of phenylephrine and metaproterenol on l-ascorbic acid-induced hepatocyte mitogenesis were examined. …
• NAID 120005352601

• がん細胞情報伝達のダイナミクスとシステムバイオロジー(<特集>疾患の数理モデル(続))

• 岡田 眞里子
• 応用数理 22(3), 193-201, 2012-09-26
• … Here is introduced an example of systems biology study regarding intracellular signal kinetics that determine cell fate. … In an effort to delineate the dynamics-oriented cell determination mechanism, we investigate time-course early transcription and intracellular signaling using both experimental and kinetic modeling approaches. …
• NAID 110009518432

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★リンクテーブル★

リンク元	「細胞内シグナル伝達機構」
関連記事	「sign」「signaling」「intracellular」「mechanism」「signal」

「細胞内シグナル伝達機構」

　　[★]

英

intracellular signal transduction mechanism

関

細胞内情報伝達機構

「sign」

　　[★]

• n.

• 徴候、兆候、サイン、(数学)符号

関

indication、manifestation、signature、stigma、stigmata、symptom、symptomatic

　 　 　 　 　 　 　 　 　 　 　 　 　 　

「signaling」

　　[★]

• n.

• シグナル伝達、情報伝達、シグナリング、信号伝達

関

signal transduction、signalling

「intracellular」

　　[★]

• adj.

• 細胞内の、細胞内での

関

adv. intracellularly

　

「mechanism」

　　[★]

• n.

• 機構、メカニズム

　 　 　 　 　 　

「signal」

　　[★]

• n.

• シグナル、信号