WordNet

a chronic skin disease characterized by dry red patches covered with scales; occurs especially on the scalp and ears and genitalia and the skin over bony prominences

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乾癬(かんせん)(慢性の非伝染性皮膚病)

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/09/23 22:44:38」(JST)

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Guttate psoriasis (also known as "eruptive psoriasis") is a type of psoriasis that presents as small (0.5-1.5 cm in diameter) lesions over the upper trunk and proximal extremities; it is found frequently in young adults.^[1]^:410^[2]^:194 Guttate psoriasis is classically triggered by a bacterial infection, usually an upper respiratory tract infection.^[3]^:726

For some people it starts as a throat infection, or strep throat. After the throat infection has cleared up the person can feel fine for several weeks before noticing the appearance of red spots. They appear small at first, like a dry red spot which is slightly itchy. When scratched or picked the top layer of dry skin is removed, leaving dry, red skin beneath with white, dry areas marking where flakes of dry skin stop and start. In the weeks that follow the spots can grow to as much as an inch in diameter. Some of the larger ones may form a pale area in the centre which is slightly yellow. Treatment is often a mild steroid, such as hydrocortisone, but this is not always effective. Other treatment include exposing the affected area of the skin to sunlight (while avoiding sunburn). The condition often but not always clears up on its own. The guttate psoriasis can occur on any part of the body, particularly the legs, arms, torso, eyelids, back, bottom, bikini-line and neck. Generally the parts of the body most affected are seen on the arms, legs, back and torso. Enthusiastic exfoliation can lead to bleeding so care and moisturisation are important to keep the affected skin healthy.

Note: It is commonly mistaken for Measles.

References

^ Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.
^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
^ Feldman SR and Clark AR (2000). "Treatment of Psoriasis: An Algorithm-Based Approach for Primary Care Physicians". Am Fam Physician 61: 725–33,736. Retrieved 30 Mar 2011.

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UpToDate Contents

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1. 滴状乾癬 guttate psoriasis
2. 乾癬の疫学、臨床症状、および診断 epidemiology clinical manifestations and diagnosis of psoriasis
3. 乾癬の治療 treatment of psoriasis
4. 乾癬性若年性特発性関節炎：病因、臨床症状、および診断 psoriatic juvenile idiopathic arthritis pathogenesis clinical manifestations and diagnosis
5. 慢性苔癬状粃糠疹 pityriasis lichenoides chronica

English Journal

Meta Analysis of the Association between Psoriasis and Human Leukocyte Antigens B.

Zhao YE, Ma JX, Hu L, Xiao SX, Zhao YL.SourceDepartment of Immunology and Pathogen Biology, Xi'an Jiaotong University College of Medicine, No.76 Yanta West Road, Xi'an, 710061, Shaanxi, China.
The British journal of dermatology.Br J Dermatol.2013 Apr 21. doi: 10.1111/bjd.12387. [Epub ahead of print]
BACKGROUND: Up to now, there is no consensus conclusion about the association between psoriasis and HLA-B.OBJECTIVES: To clarify the association between psoriasis and HLA-B.METHODS: Articles were selected, following the predefined criteria, from the case-control studies on the association between ps
PMID 23600465

Association of IL-12B gene rs6887695 polymorphism with hereditary susceptibility and clinical characterization of psoriasis vulgaris in the Chinese Han population.

Wu Y, Lu Z, Chen Y, Xue F, Chen X, Pan M, Zheng J.SourceDepartment of Dermatology, Luwan Branch, Ruijin Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, 200025, China, Yumeiwu_92@163.com.
Archives of dermatological research.Arch Dermatol Res.2013 Apr 7. [Epub ahead of print]
We aimed to investigate the role of IL-12B gene polymorphism (rs6887695) in the disease susceptibility and clinical phenotypes of psoriasis vulgaris patients in the Chinese Han population. The genotype data of the IL-12B gene polymorphism (rs6887695) in 575 psoriasis patients and 1,403 normal contro
PMID 23564024

Japanese Journal

Guttate psoriasis occurring on varicella lesions

P. KOKOLAKIS Georgios,IOANNIDOU Despina,CHOLONGITAS Evangelos,KRUGER-KRASAGAKIS Sabine
Journal of dermatology 37(9), 857-859, 2010-09-01
NAID 10027067440

Related Pictures

★リンクテーブル★

リンク元	「乾癬」「滴状乾癬」
関連記事	「guttate」

「乾癬」

Guttate psoriasis
	Back torso lesions, 30-year-old female patient
Classification and external resources
Specialty	dermatology
ICD-10	L40.4 (ILDS L40.400)
DiseasesDB	34089

　　[★]

英: psoriasis
関: 角化症

概念

慢性再発性難治性の炎症性角化症
代表的炎症性疾患のひとつで原因は不明：遺伝因子＋環境因子(生活習慣、気候、薬物)　→　HLA-B27と関連していることからautoimmune diseaseとも考えられている。
青年から中年に好発。厚い銀白色の麟屑を伴った紅斑・丘疹が出没、表皮の炎症と表皮細胞のターンオーバーの亢進を認める。