WordNet
- move something or somebody around; usually over long distances
- an exchange of molecules (and their kinetic energy and momentum) across the boundary between adjacent layers of a fluid or across cell membranes
- move while supporting, either in a vehicle or in ones hands or on ones body; "You must carry your camping gear"; "carry the suitcases to the car"; "This train is carrying nuclear waste"; "These pipes carry waste water into the river" (同)carry
- transport commercially (同)send, ship
- having an (over)abundance of flesh; "he hadnt remembered how fat she was"
- a soft greasy substance occurring in organic tissue and consisting of a mixture of lipids (mostly triglycerides); "pizza has too much fat"
- marked by great fruitfulness; "fertile farmland"; "a fat land"; "a productive vineyard"; "rich soil" (同)fertile, productive, rich
- lucrative; "a juicy contract"; "a nice fat job" (同)juicy
- having a relatively large diameter; "a fat rope"
- street name for lysergic acid diethylamide (同)back breaker, battery-acid, dose, dot, Elvis, loony toons, Lucy in the sky with diamonds, pane, superman, window pane, Zen
- any of various water-soluble compounds having a sour taste and capable of turning litmus red and reacting with a base to form a salt
- having the characteristics of an acid; "an acid reaction"
- any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
- containing or composed of fat; "fatty food"; "fat tissue" (同)fat
PrepTutorEJDIC
- (ある場所からある場所へ)…‘を'『輸送する』,運搬する《+名+from+名+to+名》 / 《文》《受動態で》(…で)…‘を'夢中にする,有頂天にする《+名+with+名》 / 〈罪人〉‘を'流刑にする / 〈U〉輸送,運送,輸送(交通)機関(transportation) / 〈C〉(軍隊や軍需品を運ぶ)輸送船,輸送機
- 『脂肪』,脂肪分 / (動物の)あぶら身 / (料理用の)油,ヘット / 肥満,太り過ぎ / 『太った』,肥満した / 『脂肪の多い』 / たっぷりとはいった,分厚い / もうかる / (土地が)肥えた / …‘を'太らせる / ふとる,肥える
- 酸性の / 酸味のある,すっぱい(sour) / (言葉・態度などが)厳しい,しんらつな / 酸 / すっぱいもの / 《俗》=LSD
- 蛋白(たんばく)質
- 脂肪質の,脂肪の多い / でぶ,太っちょ
UpToDate Contents
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- 1. 食事中の脂肪 dietary fat
- 2. 早期産児および正期産児におけるn-3長鎖多価不飽和脂肪酸（LCPUFA） n 3 long chain polyunsaturated fatty acids lcpufa for preterm and term infants
- 3. 魚油と海洋由来オメガ3脂肪酸 fish oil and marine omega 3 fatty acids
- 4. 食事または栄養補助食品による脂質低下 lipid lowering with diet or dietary supplements
- 5. 先天性代謝異常：分類 inborn errors of metabolism classification
English Journal
- Management of the aging risk factor for Parkinson's disease.
- Phillipson OT.Author information School of Medical Sciences, University of Bristol, University Walk, Bristol, UK. Electronic address: anotp@bristol.ac.uk.AbstractThe aging risk factor for Parkinson's disease is described in terms of specific disease markers including mitochondrial and gene dysfunctions relevant to energy metabolism. This review details evidence for the ability of nutritional agents to manage these aging risk factors. The combination of alpha lipoic acid, acetyl-l-carnitine, coenzyme Q10, and melatonin supports energy metabolism via carbohydrate and fatty acid utilization, assists electron transport and adenosine triphosphate synthesis, counters oxidative and nitrosative stress, and raises defenses against protein misfolding, inflammatory stimuli, iron, and other endogenous or xenobiotic toxins. These effects are supported by gene expression via the antioxidant response element (ARE; Keap/Nrf2 pathway), and by peroxisome proliferator-activated receptor gamma co-activator 1 alpha (PGC-1 alpha), a transcription coactivator, which regulates gene expression for energy metabolism and mitochondrial biogenesis, and maintains the structural integrity of mitochondria. The effectiveness and synergies of the combination against disease risks are discussed in relation to gene action, dopamine cell loss, and the accumulation and spread of pathology via misfolded alpha-synuclein. In addition there are potential synergies to support a neurorestorative role via glial derived neurotrophic factor expression.
- Neurobiology of aging.Neurobiol Aging.2014 Apr;35(4):847-57. doi: 10.1016/j.neurobiolaging.2013.10.073. Epub 2013 Oct 10.
- The aging risk factor for Parkinson's disease is described in terms of specific disease markers including mitochondrial and gene dysfunctions relevant to energy metabolism. This review details evidence for the ability of nutritional agents to manage these aging risk factors. The combination of alpha
- PMID 24246717
- Regulation of peroxisomal lipid metabolism: The role of acyl-CoA and coenzyme A metabolizing enzymes.
- Hunt MC1, Tillander V2, Alexson SE2.Author information 1Dublin Institute of Technology, College of Sciences & Health, School of Biological Sciences, Kevin Street, Dublin 8, Ireland. Electronic address: mary.hunt@dit.ie.2Karolinska Institutet, Department of Laboratory Medicine, Division of Clinical Chemistry, Karolinska University Hospital, SE 141 86, Stockholm, Sweden.AbstractPeroxisomes are nearly ubiquitous organelles involved in a number of metabolic pathways that vary between organisms and tissues. A common metabolic function in mammals is the partial degradation of various (di)carboxylic acids via α- and β-oxidation. While only a small number of enzymes catalyze the reactions of β-oxidation, numerous auxiliary enzymes have been identified to be involved in uptake of fatty acids and cofactors required for β-oxidation, regulation of β-oxidation and transport of metabolites across the membrane. These proteins include membrane transporters/channels, acyl-CoA thioesterases, acyl-CoA:amino acid N-acyltransferases, carnitine acyltransferases and nudix hydrolases. Here we review the current view of the role of these auxiliary enzymes in peroxisomal lipid metabolism and propose that they function in concert to provide a means to regulate fatty acid metabolism and transport of products across the peroxisomal membrane.
- Biochimie.Biochimie.2014 Mar;98C:45-55. doi: 10.1016/j.biochi.2013.12.018. Epub 2014 Jan 2.
- Peroxisomes are nearly ubiquitous organelles involved in a number of metabolic pathways that vary between organisms and tissues. A common metabolic function in mammals is the partial degradation of various (di)carboxylic acids via α- and β-oxidation. While only a small number of enzymes catalyze t
- PMID 24389458
- Loss of NDG-4 extends lifespan and stress resistance in Caenorhabditis elegans.
- Brejning J, Nørgaard S, Schøler L, Morthorst TH, Jakobsen H, Lithgow GJ, Jensen LT, Olsen A.Author information Department of Molecular Biology and Genetics, Aarhus University, Gustav Wieds Vej 10C, Aarhus, 8000-DK, Denmark.AbstractNDG-4 is a predicted transmembrane acyltransferase protein that acts in the distribution of lipophilic factors. Consequently, ndg-4 mutants lay eggs with a pale appearance due to lack of yolk, and they are resistant to sterility caused by dietary supplementation with the long-chain omega-6 polyunsaturated fatty acid dihommogamma-linolenic acid (DGLA). Two other proteins, NRF-5 and NRF-6, a homolog of a mammalian secreted lipid binding protein and a NDG-4 homolog, respectively, have previously been shown to function in the same lipid transport pathway. Here, we report that mutation of the NDG-4 protein results in increased organismal stress resistance and lifespan. When NDG-4 function and insulin/IGF-1 signaling are reduced simultaneously, maximum lifespan is increased almost fivefold. Thus, longevity conferred by mutation of ndg-4 is partially overlapping with insulin signaling. The nuclear hormone receptor NHR-80 (HNF4 homolog) is required for longevity in germline less animals. We find that NHR-80 is also required for longevity of ndg-4 mutants. Moreover, we find that nrf-5 and nrf-6 mutants also have extended lifespan and increased stress resistance, suggesting that altered lipid transport and metabolism play key roles in determining lifespan.
- Aging cell.Aging Cell.2014 Feb;13(1):156-64. doi: 10.1111/acel.12165. Epub 2013 Nov 28.
- NDG-4 is a predicted transmembrane acyltransferase protein that acts in the distribution of lipophilic factors. Consequently, ndg-4 mutants lay eggs with a pale appearance due to lack of yolk, and they are resistant to sterility caused by dietary supplementation with the long-chain omega-6 polyunsat
- PMID 24286221
Japanese Journal
- Neuroprotective and Ameliorative Actions of Polyunsaturated Fatty Acids Against Neuronal Diseases : Implication of Fatty Acid-Binding Proteins (FABP) and G Protein-Coupled Receptor 40 (GPR40) in Adult Neurogenesis
- BONEVA Nadezhda B.,KIKUCHI Mitsuru,MINABE Yoshio,YAMASHIMA Tetsumori
- Journal of pharmacological sciences 116(2), 163-172, 2011-06-20
- … Adult neurogenesis is modulated by polyunsaturated fatty acids (PUFA) such as docosahexaenoic and arachidonic acids that are essential for normal brain development, maintenance, and function. … PUFA are functionally linked with chaperons called fatty acid–binding proteins (FABP). … FABP uptake and transport PUFA to different intracellular organelles. …
- NAID 10029894501
- Lipid Transport Mediated by Arabidopsis TGD Proteins is Unidirectional from the Endoplasmic Reticulum to the Plastid
- XU Changcheng,MOELLERING Eric R.,MUTHAN Bagyalakshmi,FAN Jilian,BENNING Christoph
- Plant and cell physiology 51(6), 1019-1028, 2010-06-01
- NAID 10027350161
Related Links
- したがって、このプロセスを制御する脂肪酸輸送たんぱく質（Fatty Acid Transport Proteins: FATP）の理解は、生化学研究や薬剤開発にたいへん重要です。 FATPは、 進化的にはよく保存されたたんぱく質ファミリーのひとつで、ヒトゲノムには6種類の FATPが見 ...
Related Pictures
★リンクテーブル★
| リンク元 | 「脂肪酸輸送体」「脂肪酸輸送タンパク質」「脂肪酸トランスポーター」 |
| 関連記事 | 「transport」「transport protein」「fatty」「fat」 |
「脂肪酸輸送体」
「脂肪酸輸送タンパク質」
「脂肪酸トランスポーター」
「transport」
- n.
- v.
- 輸送する、運搬する、運ぶ
「transport protein」
「fatty」
- adj.
- 脂肪性の、脂肪質の
「fat」