WordNet

be a contributing factor; "make things factor into a companys profitability"
any of the numbers (or symbols) that form a product when multiplied together
an independent variable in statistics
anything that contributes causally to a result; "a number of factors determined the outcome"
consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"
a concept whose truth can be proved; "scientific hypotheses are not facts"
a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"
a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"
an addition to the length of something (同)extension
the act of lengthening something
the quality of being elongated

PrepTutorEJDIC

(…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize
〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行
〈U〉伸長,延長 / 〈C〉伸長部,延長部

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/06/05 16:13:31」(JST)

wiki en

Elongation factors are a set of proteins that are used in protein synthesis in the cell. In the ribosome, they facilitate translational elongation, from the formation of the first peptide bond to the formation of the last one.

Elongation is the most rapid step in translation:

in prokaryotes it proceeds at a rate of 15 to 20 amino acids added per second (about 60 nucleotides per second)
in eukaryotes the rate is about two amino acids per second.

Elongation factors play a role in orchestrating the events of this process, and in ensuring the 99.99% accuracy of translation at this speed.

Elongation factors are also a target for pathogen toxins. Corynebacterium diphtheriae produces the diphtheria toxin that alters protein function in the host by inactivating elongation factor (EF-2). This causes pharyngitis and pseudomembranous inflammation in the throat.

Pseudomonas aeruginosa's exotoxin A also inhibits EF-2.

References

Alberts, B. et al. (2002). Molecular Biology of the Cell, 4th ed. New York: Garland Science. ISBN 0-8153-3218-1
Berg, J. M. et al. (2002). Biochemistry, 5th ed. New York: W.H. Freeman and Company. ISBN 0-7167-3051-0
Singh, B. D. (2002). Fundamentals of Genetics, New Delhi, India: Kalyani Publishers. ISBN 81-7663-109-4

External links

Elongation Factor at the US National Library of Medicine Medical Subject Headings (MeSH)
EC 3.6.5.3

UpToDate Contents

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English Journal

Phosphorylation of Runx2, induced by cyclic mechanical tension via ERK1/2 pathway, contributes to osteodifferentiation of human periodontal ligament fibroblasts.

Ren D1, Wei F2, Hu L2, Yang S2, Wang C1, Yuan X2.
Journal of cellular physiology.J Cell Physiol.2015 Oct;230(10):2426-36. doi: 10.1002/jcp.24972.
Occlusal force is an important stimulus for maintaining periodontal homeostasis. This is attributed to the quality of human periodontal ligament fibroblasts (hPDLFs) that could transfer occlusal force into biological signals modulating osteoblst differentiation. However, few studies investigated the
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Combined effects of raw materials and solvent systems on the preparation and properties of regenerated cellulose fibers.

Chen J1, Guan Y1, Wang K2, Zhang X1, Xu F1, Sun R3.
Carbohydrate polymers.Carbohydr Polym.2015 Sep 5;128:147-53. doi: 10.1016/j.carbpol.2015.04.027. Epub 2015 Apr 21.
To investigate the combined effects of materials and solvents on the preparation, structural and mechanical properties of regenerated cellulose fibers, four cellulosic materials (microcrystalline cellulose, cotton linter pulp, bamboo pulp and bleached softwood sulfite dissolving pulp) and six non-de
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Oral squamous cancer cell exploits hnRNP A1 to regulate cell cycle and proliferation.

Yu C1, Guo J1, Liu Y2, Jia J1, Jia R1, Fan M1.
Journal of cellular physiology.J Cell Physiol.2015 Sep;230(9):2252-61. doi: 10.1002/jcp.24956.
Oral squamous cell carcinoma (OSCC) is a common human malignant tumor with high mortality. So far, the molecular pathogenesis of OSCC remains largely unclear. Heterogeneous nuclear ribonucleoprotein (hnRNP) A1 is an important multi-function splicing factor and closely related to tumorigenesis. hnRNP
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Japanese Journal

Phylogenetic relationships among biological species of Armillaria from China

Mycoscience : official journal of the Mycological Society of Japan 56(5), 530-541, 2015-09
NAID 40020592436

Oxidation of translation factor EF-G transiently retards the translational elongation cycle in Escherichia coli

The journal of biochemistry 158(2), 165-172, 2015-08
NAID 40020554133

Phytochrome-mediated regulation of cell division and growth during regeneration and sporeling development in the liverwort Marchantia polymorpha (JPR Symposium : Reprogramming of plant cells as adaptive strategies)

Journal of plant research 128(3), 407-421, 2015-05
NAID 120005674661

Related Pictures

★リンクテーブル★

リンク元	「ポリペプチド鎖伸長因子」「EF」「エロンゲーション因子」「伸長因子」「エロンゲーションファクター」
拡張検索	「peptide elongation factor」「peptide elongation factor Tu」「peptide elongation factor 2」「peptide elongation factor G」
関連記事	「elongation」「fact」「factor」