WordNet

be a contributing factor; "make things factor into a companys profitability"
any of the numbers (or symbols) that form a product when multiplied together
an independent variable in statistics
anything that contributes causally to a result; "a number of factors determined the outcome"
consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"
a concept whose truth can be proved; "scientific hypotheses are not facts"
a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"
a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"
an addition to the length of something (同)extension
the act of lengthening something
the quality of being elongated
amide combining the amino group of one amino acid with the carboxyl group of another; usually obtained by partial hydrolysis of protein

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/10/19 04:29:43」(JST)

Eukaryotic elongation factors are very similar to those in prokaryotes.

Elongation in eukaryotes is carried out with two elongation factors: eEF-1 and eEF-2.

The first is eEF-1, and has two subunits, α and βγ. α acts as counterpart to prokaryotic EF-Tu, mediating the entry of the aminoacyl tRNA into a free site of the ribosome. βγ acts as counterpart to prokaryotic EF-Ts, serving as the guanine nucleotide exchange factor for α, catalyzing the release of GDP from α.

The second elongation factor is eEF-2, the counterpart to prokaryotic EF-G, catalyzing the translocation of the tRNA and mRNA down the ribosome at the end of each round of polypeptide elongation.

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Enhanced anti-colon cancer immune responses with modified eEF2-derived peptides.

Sun W1, Wei X2, Niu A3, Ma X4, Li JJ5, Gao D2.
Cancer letters.Cancer Lett.2015 Dec 1;369(1):112-23. doi: 10.1016/j.canlet.2015.08.002. Epub 2015 Aug 21.
Eukaryotic elongation factor-2 (eEF2) is overexpressed in many human cancers and is an attractive target for cancer immunotherapy. The eEF2 derived polypeptides have been shown to be able to induce cytotoxic T lymphocytes from healthy donor. Here, we demonstrate the evidence indicating that modifica
PMID 26304717

Phosphatase control of 4E-BP1 phosphorylation state is central for glycolytic regulation of retinal protein synthesis.

Gardner TW1, Abcouwer SF2, Losiewicz MK2, Fort PE3.
American journal of physiology. Endocrinology and metabolism.Am J Physiol Endocrinol Metab.2015 Sep 15;309(6):E546-56. doi: 10.1152/ajpendo.00180.2015. Epub 2015 Jul 21.
Control of protein synthesis in insulin-responsive tissues has been well characterized, but relatively little is known about how this process is regulated in nervous tissues. The retina exhibits a relatively high protein synthesis rate, coinciding with high basal Akt and metabolic activities, with t
PMID 26199279

Loss of diphthamide pre-activates NF-κB and death receptor pathways and renders MCF7 cells hypersensitive to tumor necrosis factor.

Stahl S1, da Silva Mateus Seidl AR2, Ducret A3, Kux van Geijtenbeek S3, Michel S3, Racek T4, Birzele F4, Haas AK1, Rueger R4, Gerg M5, Niederfellner G2, Pastan I6, Brinkmann U7.
Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2015 Aug 25;112(34):10732-7. doi: 10.1073/pnas.1512863112. Epub 2015 Aug 10.
The diphthamide on human eukaryotic translation elongation factor 2 (eEF2) is the target of ADP ribosylating diphtheria toxin (DT) and Pseudomonas exotoxin A (PE). This modification is synthesized by seven dipthamide biosynthesis proteins (DPH1-DPH7) and is conserved among eukaryotes and archaea. We
PMID 26261303

Eukaryotic Elongation Factor 1A2 (eEF1A2) Participates in the Expression of Antiadhesive Effect of FNIII14, a Peptide Derived from Fibronectin

Eukaryotic Translation Elongation Factor (eEF1A) Serves as a Membrane Receptor Mediating Anti-Adhesive Effect of Peptide FNIII14

近藤洋介,權娟大,宮崎智
研究報告バイオ情報学（BIO） 2011-BIO-27(12), 1-6, 2011-11-24
… を構築するタンパク質であるが，フィブロネクチンの 22-mer のフラグメント FNIII14 は足場への接着を媒介する分子インテグリンの機能を抑制する．最近，タンパク質翻訳伸長因子 eEF1A（Eukaryotic Elongation Factor 1A）が FNIII14 の細胞膜受容体であることが示唆された．eEF1A は細胞質でペプチド鎖伸長に関わる因子であり，細胞膜上での機能はあまり知られていない．細胞膜上での eEF1A の機能を解明すれば …
NAID 110008694774