WordNet

a substance that exerts some force or effect
a businessman who buys or sells for another in exchange for a commission (同)factor, broker
any agent or representative of a federal agency or bureau (同)federal agent
a representative who acts on behalf of other persons or organizations
an active and efficient cause; capable of producing a certain effect; "their research uncovered new disease agents"
how long something has existed; "it was replaced because of its age"
a time of life (usually defined in years) at which some particular qualification or power arises; "she was now of school age"; "tall for his eld" (同)eld
begin to seem older; get older; "The death of his wife caused him to age fast"
make older; "The death of his child aged him tremendously"
relating to or involved in therapy; "therapeutic approach to criminality" (同)therapeutical
branch of medicine concerned with the treatment of disease
mental deterioration of organic or functional origin (同)dementedness

PrepTutorEJDIC

『代理人』;周旋人 / 働き(作用)を起こすもの;作用物,薬剤 / (政府機関,特にFBI,CIAなどの)部員,機関員
〈U〉(一般に)『年齢』,寿命;〈C〉(個々の)『年齢』,年 / 〈U〉成年(おとなとしての資格・権利を得る年齢;通例18または21歳) / 〈U〉『老齢』;《集合的に》老人たち / 〈U〉(人生の)『一時期』;〈C〉世代(generation) / 〈U〉〈C〉《しばしばA-》(歴史上の)『時代』 / 〈C〉《話》長い間 / 年をとる,ふける;〈物が〉古くなる / 〈年〉'を'とらせる;〈物〉'を'古びさせる
治療[上]の
治療学
(医学的な)痴呆(ちほう)

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The Japanese Angelica acutiloba root and yokukansan increase hippocampal acetylcholine level, prevent apoptosis and improve memory in a rat model of repeated cerebral ischemia.

Nogami-Hara A1, Nagao M2, Takasaki K1, Egashira N3, Fujikawa R1, Kubota K4, Watanabe T4, Katsurabayashi S1, Hatip FB5, Hatip-Al-Khatib I6, Iwasaki K4.
Journal of ethnopharmacology.J Ethnopharmacol.2018 Mar 25;214:190-196. doi: 10.1016/j.jep.2017.12.025. Epub 2017 Dec 19.
PMID 29269276

Rationale and design of the CAROLINA® - cognition substudy: a randomised controlled trial on cognitive outcomes of linagliptin versus glimepiride in patients with type 2 diabetes mellitus.

Biessels GJ1, Janssen J2,3, van den Berg E2,4, Zinman B5, Espeland MA6, Mattheus M7, Johansen OE8; CAROLINA® investigators.
BMC neurology.BMC Neurol.2018 Jan 15;18(1):7. doi: 10.1186/s12883-018-1014-7.
PMID 29334906

Thioredoxin-albumin fusion protein prevents copper enhanced zinc-induced neurotoxicity via its antioxidative activity.

Tanaka KI1, Shimoda M1, Chuang VTG2, Nishida K3, Kawahara M1, Ishida T4, Otagiri M5, Maruyama T3, Ishima Y6.
International journal of pharmaceutics.Int J Pharm.2018 Jan 15;535(1-2):140-147. doi: 10.1016/j.ijpharm.2017.11.012. Epub 2017 Nov 6.
PMID 29122608

Uchida Satoko,Endo Shin,Akita Kenji [他],Ohta Tsunetaka,Fukuda Shigeharu
Biological and Pharmaceutical Bulletin 35(10), 1831-1835, 2012
… Although the mechanism through which NK-4 reverses cognitive impairments in scopolamine-treated mice remains unclear, these data suggest that NK-4 may have potential as a therapeutic agent for the treatment of dementia. …
NAID 130001872367

竹尾聰,高木教夫,高木慶子
藥學雜誌 127(11), 1813-1823, 2007-11-01
… Cerebral ischemia causes an irreversible and neurodegenerative disorder that may lead to progressive dementia and global cognitive deterioration. … To elucidate therapeutic potencies of HGF for ischemic brain injuries, we examined effects of HGF on ischemia-induced learning and memory dysfunction, neuronal cell death and endothelial cell damage by using the 4-vessel occlusion model and the microsphere embolism model in rats. …
NAID 110006439684

Memory-Enhancing Effect of a Supercritical Carbon Dioxide Fluid Extract of the Needles of Abies koreana on Scopolamine-Induced Amnesia in Mice

Kim Kanghyun,Bu Youngmin,Jeong Seungil [他],LIM Jongpil,KWON Youngan,CHA Dong Seok,KIM Jinmo,JEON Sora,EUN Jaesoon,JEON Hoon
Bioscience, biotechnology, and biochemistry 70(8), 1821-1826, 2006-08-23
… may be a useful therapeutic agent against such amnesia-inducing diseases as Alzheimer and vascular dementia. …
NAID 10018527825