WordNet

markedly subnormal in structure or function or intelligence or behavior; "defective speech"
having a defect; "I returned the appliance because it was defective" (同)faulty
a harmful or corrupting agency; "bigotry is a virus that must not be allowed to spread"; "the virus of jealousy is latent in everyone"
(virology) ultramicroscopic infectious agent that replicates itself only within cells of living hosts; many are pathogenic; a piece of nucleic acid (DNA or RNA) wrapped in a thin coat of protein
a software program capable of reproducing itself and usually capable of causing great harm to files or other programs on the same computer; "a true virus cannot spread to another computer without human assistance" (同)computer virus
intrusive in a meddling or offensive manner; "an interfering old woman"; "bustling about self-importantly making an officious nuisance of himself"; "busy about other peoples business" (同)meddlesome, meddling, officious, busy, busybodied

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Infection of Mouse Macrophages by Seasonal Influenza Viruses Can Be Restricted at the Level of Virus Entry and at a Late Stage in the Virus Life Cycle.

Londrigan SL1, Short KR1, Ma J1, Gillespie L1, Rockman SP2, Brooks AG1, Reading PC3.
Journal of virology.J Virol.2015 Dec 15;89(24):12319-29. doi: 10.1128/JVI.01455-15. Epub 2015 Sep 30.
Airway epithelial cells are susceptible to infection with seasonal influenza A viruses (IAV), resulting in productive virus replication and release. Macrophages (MΦ) are also permissive to IAV infection; however, virus replication is abortive. Currently, it is unclear how productive infection of M�
PMID 26423941

Identification of an ourmiavirus 30K movement protein amino acid residues involved in symptomatology, viral movement, subcellular localization and tubule formation.

Margaria P1, Anderson CT2, Turina M3, Rosa C1.
Molecular plant pathology.Mol Plant Pathol.2015 Dec 6. doi: 10.1111/mpp.12348. [Epub ahead of print]
Several plant viruses encode movement proteins (MP) classified in the 30K superfamily. Despite a great functional diversity, alignment analysis of MP sequences belonging to the 30K superfamily revealed the presence of a central core region, including amino acids potentially critical for MP structure
PMID 26637973

Ikeda Y1, Makino A2,3, Matchett WE1, Holditch SJ1, Lu B1, Dietz AB4, Tomonaga K2,5,6.
Gene therapy.Gene Ther.2015 Dec 3. doi: 10.1038/gt.2015.108. [Epub ahead of print]
Genetically modified stem and progenitor cells have emerged as a promising regenerative platform in the treatment of genetic and degenerative disorders, highlighted by their successful therapeutic use in inherent immunodeficiencies. However, biosafety concerns over insertional mutagenesis resulting
PMID 26632671

鈴木信弘
ウイルス 64(1), 11-24, 2014
　菌類は未同定，未報告の種も含めると百万種を超えると言われる．そこにはそれらを宿主とする多種多様なマイコウイルス（菌類ウイルス）の世界も広がっている．ここ20年に渡る一握りのマイコウイルスの研究から，精製したウイルスの粒子に感染性があることが証明されて人工接種法の開発に至り，ウイルス研究に必要な他の技術革新ももたらされた．植物病原糸状菌の一種であるクリ胴枯病菌は，マイコウイルス研究のモデル宿主菌と …
NAID 130004922974